Click here to switch to the map view.

The map label for this gene is 15922657

Identifier: 15922657

GI number: 15922657

Start: 2328822

End: 2329811

Strand: Direct

Name: 15922657

Synonym: ST2324

Alternate gene names: NA

Gene position: 2328822-2329811 (Clockwise)

Preceding gene: 15922654

Following gene: 15922667

Centisome position: 86.42

GC content: 34.34

Gene sequence:

>990_bases
GTGTCTTTAATACCACTAATTTATTCAGATGTTTATTTATTACACAAGCCCAAACATACGCATTCAGAGAATCCAGATAG
AATAAAACGTGCTCTGGAAGAGTTAAAAAATTATCCCATAATTTCCCCACAAAAAGTATCAGAAGAAGAAGTTAAATTAA
TTCATGATGAAGATTACATTAACCTAGTTAAATCATCTAGCGAGAAGGAAAGTATGATTGATGCAGACACTTACACTAGC
AAAGAAACATTTAATGTGGCACTCTACGCTCTAGGTGGGGCATTAAAAGCATTTGAGACTAATGGGTTTGGTTTGTTAAG
ACCACCAGGTCATCATGCTGGTAGGTTTGGAAAGGCATTTGGTGCCCCAACACTAGGTTTTTGTATTTTCAATAATATCG
CTTTTCCTATAAGAAAATACGCCTTAACGAAGGTGTTAATTATCGATTTTGATGTGCATTATGGTAACGGAACTCAAGAT
ATATTCTGGAACGATCCGGAGGTTGTACATATAGATATTCATCAAGATCCAAGAACTATATATCCTGGTACTGGATTTCC
AGATATGATAGGAGGAAAAGATGCTGAAGGCACAAAGATTAATCTATTAATTCCACCATTAGGAGGGGACGATTTATATG
AAGAGTTAATACCTATCATACAATCTGTAATTGATGACTTTAAACCTAAAATAATAGCCTATTCTGCTGGTTTCGATGCT
TTTGAGGGTGATGGACTTGCTAGTGTAAGAGCTACTGAGTGGACATATTATAATATGGGTTTACTCTCAAATAGATTTGA
AAGGAAATATGCAGTTCTAGAAGGTGGTTATGGTGTAGGTTTAATAAGAGGACTTAAGGCGTTTATATACGGATTACAAG
GAGAAAAGAAGGTATATTCTAAAAATACATCATCAGATGCTGTTAAGAGTAGATTCAGAAATTATCTATCTGAAGAAAAG
ATGATATTAAGAGAATTCTGGAAAATTTAA

Upstream 100 bases:

>100_bases
CCAAGAATTACATAATCAATCATTCTCTCTTTCATTAGTTCTCTGAGTCTAGCTATCCTCTTCATATAGCTTTTTTAAGC
AAAAGCCCTATATAACTTCT

Downstream 100 bases:

>100_bases
CAGGTATAATAGCATTTTAATGCTAAATTGTATGCAGCATTAAAGTCTCTATCTGCTTTGAATCCGCATGCTGGACATAC
AAATAAAGGCCCTAAAACTT

Product: acetoin utilization protein AcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSLIPLIYSDVYLLHKPKHTHSENPDRIKRALEELKNYPIISPQKVSEEEVKLIHDEDYINLVKSSSEKESMIDADTYTS
KETFNVALYALGGALKAFETNGFGLLRPPGHHAGRFGKAFGAPTLGFCIFNNIAFPIRKYALTKVLIIDFDVHYGNGTQD
IFWNDPEVVHIDIHQDPRTIYPGTGFPDMIGGKDAEGTKINLLIPPLGGDDLYEELIPIIQSVIDDFKPKIIAYSAGFDA
FEGDGLASVRATEWTYYNMGLLSNRFERKYAVLEGGYGVGLIRGLKAFIYGLQGEKKVYSKNTSSDAVKSRFRNYLSEEK
MILREFWKI

Sequences:

>Translated_329_residues
MSLIPLIYSDVYLLHKPKHTHSENPDRIKRALEELKNYPIISPQKVSEEEVKLIHDEDYINLVKSSSEKESMIDADTYTS
KETFNVALYALGGALKAFETNGFGLLRPPGHHAGRFGKAFGAPTLGFCIFNNIAFPIRKYALTKVLIIDFDVHYGNGTQD
IFWNDPEVVHIDIHQDPRTIYPGTGFPDMIGGKDAEGTKINLLIPPLGGDDLYEELIPIIQSVIDDFKPKIIAYSAGFDA
FEGDGLASVRATEWTYYNMGLLSNRFERKYAVLEGGYGVGLIRGLKAFIYGLQGEKKVYSKNTSSDAVKSRFRNYLSEEK
MILREFWKI
>Mature_328_residues
SLIPLIYSDVYLLHKPKHTHSENPDRIKRALEELKNYPIISPQKVSEEEVKLIHDEDYINLVKSSSEKESMIDADTYTSK
ETFNVALYALGGALKAFETNGFGLLRPPGHHAGRFGKAFGAPTLGFCIFNNIAFPIRKYALTKVLIIDFDVHYGNGTQDI
FWNDPEVVHIDIHQDPRTIYPGTGFPDMIGGKDAEGTKINLLIPPLGGDDLYEELIPIIQSVIDDFKPKIIAYSAGFDAF
EGDGLASVRATEWTYYNMGLLSNRFERKYAVLEGGYGVGLIRGLKAFIYGLQGEKKVYSKNTSSDAVKSRFRNYLSEEKM
ILREFWKI

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI30795204, Length=319, Percent_Identity=30.7210031347962, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI30795202, Length=319, Percent_Identity=30.7210031347962, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI17158039, Length=319, Percent_Identity=30.7210031347962, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI169234807, Length=333, Percent_Identity=29.7297297297297, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI153085395, Length=371, Percent_Identity=27.4932614555256, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI13128864, Length=295, Percent_Identity=30.1694915254237, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI20070354, Length=290, Percent_Identity=30.6896551724138, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI148539870, Length=348, Percent_Identity=28.448275862069, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI62750349, Length=333, Percent_Identity=28.8288288288288, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI62750347, Length=333, Percent_Identity=28.8288288288288, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI226529806, Length=178, Percent_Identity=33.7078651685393, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI13128860, Length=252, Percent_Identity=25.7936507936508, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI8923769, Length=229, Percent_Identity=22.707423580786, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI293336691, Length=252, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI13128862, Length=223, Percent_Identity=24.2152466367713, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=360, Percent_Identity=28.6111111111111, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17540332, Length=360, Percent_Identity=28.6111111111111, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193206283, Length=360, Percent_Identity=28.6111111111111, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193209491, Length=327, Percent_Identity=29.9694189602446, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25154022, Length=314, Percent_Identity=27.7070063694268, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17537347, Length=287, Percent_Identity=32.0557491289199, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25154020, Length=305, Percent_Identity=27.8688524590164, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508561, Length=266, Percent_Identity=25.187969924812, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324307, Length=308, Percent_Identity=28.8961038961039, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325325, Length=173, Percent_Identity=31.2138728323699, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=247, Percent_Identity=22.6720647773279, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24642146, Length=300, Percent_Identity=32.6666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24642144, Length=300, Percent_Identity=32.6666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24642142, Length=300, Percent_Identity=32.6666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281360899, Length=300, Percent_Identity=32.6666666666667, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24641720, Length=311, Percent_Identity=27.9742765273312, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360799, Length=311, Percent_Identity=27.9742765273312, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281360801, Length=311, Percent_Identity=27.9742765273312, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24657891, Length=263, Percent_Identity=26.9961977186312, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24644244, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 37090; Mature: 36959

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIPLIYSDVYLLHKPKHTHSENPDRIKRALEELKNYPIISPQKVSEEEVKLIHDEDYI
CCCCHHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCHHH
NLVKSSSEKESMIDADTYTSKETFNVALYALGGALKAFETNGFGLLRPPGHHAGRFGKAF
HHHHCCCHHHHHCCCCCCCCCCHHEEEEEECCCHHEEEECCCEEEECCCCCCCCCCHHHC
GAPTLGFCIFNNIAFPIRKYALTKVLIIDFDVHYGNGTQDIFWNDPEVVHIDIHQDPRTI
CCCHHHHHHHHCCHHHHHHHHHEEEEEEEEEEEECCCCCCEEECCCCEEEEEECCCCCEE
YPGTGFPDMIGGKDAEGTKINLLIPPLGGDDLYEELIPIIQSVIDDFKPKIIAYSAGFDA
CCCCCCCHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
FEGDGLASVRATEWTYYNMGLLSNRFERKYAVLEGGYGVGLIRGLKAFIYGLQGEKKVYS
CCCCCCCEEEEEEEEEEECHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCHHHC
KNTSSDAVKSRFRNYLSEEKMILREFWKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLIPLIYSDVYLLHKPKHTHSENPDRIKRALEELKNYPIISPQKVSEEEVKLIHDEDYI
CCCHHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCHHH
NLVKSSSEKESMIDADTYTSKETFNVALYALGGALKAFETNGFGLLRPPGHHAGRFGKAF
HHHHCCCHHHHHCCCCCCCCCCHHEEEEEECCCHHEEEECCCEEEECCCCCCCCCCHHHC
GAPTLGFCIFNNIAFPIRKYALTKVLIIDFDVHYGNGTQDIFWNDPEVVHIDIHQDPRTI
CCCHHHHHHHHCCHHHHHHHHHEEEEEEEEEEEECCCCCCEEECCCCEEEEEECCCCCEE
YPGTGFPDMIGGKDAEGTKINLLIPPLGGDDLYEELIPIIQSVIDDFKPKIIAYSAGFDA
CCCCCCCHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
FEGDGLASVRATEWTYYNMGLLSNRFERKYAVLEGGYGVGLIRGLKAFIYGLQGEKKVYS
CCCCCCCEEEEEEEEEEECHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCHHHC
KNTSSDAVKSRFRNYLSEEKMILREFWKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]