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The map label for this gene is gltB [C]

Identifier: 15922526

GI number: 15922526

Start: 2205306

End: 2207213

Strand: Direct

Name: gltB [C]

Synonym: ST2198

Alternate gene names: 15922526

Gene position: 2205306-2207213 (Clockwise)

Preceding gene: 15922525

Following gene: 15922527

Centisome position: 81.84

GC content: 39.36

Gene sequence:

>1908_bases
ATGTCTGCTCCACTCTATTTGGGAGATATGTCTTATGGTGCTTTAAGCGGTAATCCTAATATAATAATAGCGAGAGCTGC
GGATTTAACGGGAACTTTAGCTGGTACTGGTGAGGGGGGTTTACATCCGGAAGTTGCTAAATCTAAGAGGATTTTTGTTC
AATGGGCTTCAGCCCGTTTTGGTGTTGATTTTGATGTTTTAATGCATGGAGCTGGAATTGTTATTAAGATTGGACAAGGT
GCTAAGCCAGGTATTGGTGGTCATTTACCCGGGAGTAAAGTTACCGAACCCATTTCTCTTACTAGACGAATACCAGTTGG
TATTGATGCTATTTCTCCAGCCCCCCATCATGATATTTATTCTATTGAGGATTTGGGTCAAAGGATTGAAGCTTTGAAGG
AAGCTACTGGTAAGCCTGTCTTTGTTAAGGTTGCTGCTACTAACTATATTCCTTATATAGTGTCTGGAATTGCAAGGATG
GGTGCAGATGGTGTTATAATTGATGGTCATGGTGCTGGTACTGGTGCTACTCCCATTGTTATAAGGGATAATGTTGGCAT
TCCGATCGAGTTAGCAGTAGCTTCAGCTGATAAGGTTTTGCGTGAACAAGGTATGAGGGATAACTTTTATATTATTGCAG
CAGGTAGGGTTGCTGATGCTACTGATGCAGCTAAGTTAATTGCTTTAGGGGCGGATGTTGTTAGTGTAGGTACGGGGGCT
TTGATTGCAATGGGTTGTGTTATGGTTCATAAGTGTCATATTGGTTCTTGTCCAACAGCTCTAACGAATAAGATTGACGG
TAGTAGGATGGTCGACATAGATTTTGGACTTAAAGTCTTAGTTAACTATATTCATGGCTTTTCTCTCGAACTAGCTAACA
TTCTGGATAATTTGGGTCTCTCAAGCATAGATGAACTTAAGGGAAGGAGGGATCTGTTAGTAGGTAAGGGTTTATCCAGG
GAGACTTTGTCTGTCTTAGGTATTGAGGGAGAAGAGGAAGAATTGCCACCTAAGCTTGGCGAGTTATGGTCTAGGAGGAG
AAAAGTGTATTTACATGAGTTAATCAATAAGGGCGACCCCGTGATTACCAGTATGGGTAGTACTGCACCCCCAGACGTTG
AAAAACCCGCAAGGATTGTGGATTGGTTAAGAAGTGATGGTGCTCAAGTTACTAGACCTTCAATCGATCCTTATAGAGAA
GATATTGATACGAGCTTTTATTTAGCTGGTGGAAGGATTTATCTCTCTTTACCAGTAATTTTTGATATTATTGATGCACC
AGAAGATGAGAGAAATGCTCTACAGTGGGCTTCTTTGGCTTTAAGTTCTGCTGTATTTACTGATGTTACTCCAAGATATT
ATGAAGATATTTCGATAAGTCATGATGGTAAGGGTATAATTAAATGGAGTAAGAATTATGAGAGTGGTAGTTATATCTTA
TTGCCGAGTAATGAGGAGGCTCTTGAGGAAGTTGTAGAATTGAAGGGTATACCAGGTTTTATTATTGATGAGGATTTAGG
TAATGAAGATCTTGAGGTCGTTATTTCAGAGATAGACACTAAGTTAAAGAGAATGGGAATAAGGAAGAAATTTGATTTAA
TTGCAAAGTCTTCTAGGATAAGGGATTCGGGGGACGTTTTTAAGTTTGTTGCCTTAGGTGCAGATTCTGTTATAATATCT
TATAAAGTGTTTGAAGTCGCTTTAGGAGAAGGAAGCAGAAGTGACTTGAAGAGTAAGGCATTTAATTTAATTTCTGGTTT
TAAGAAAGAGATCGCTTTGTTAGCTGGCGCTGCTGGCGTTTACTCTGTTCAATCTACTTTAACCGGAAATAGAGAACTTT
TAAGAGCAATAAATTTGAATTCTTATCTTTTACAAAAGCTTAGGGTTAAGGTGGCTGGTTCTCTATGA

Upstream 100 bases:

>100_bases
CTCTTTAAGGATTCTTGATAGAGTTCGTTTTAAAAAAGAGGATTCTAAAATTAGTGATACTCCAAAAGCTAGGACTTTTA
CTAAACTAGCTGGTATAGAA

Downstream 100 bases:

>100_bases
TTCACCCATCTGGTTGTGGTGTTTTAGGTATATTAAGAAAAAAGAGTGCAAATAAGATTTCCGGTGAGATGGTAGTTAGG
GGGATTGAGAGAGTAAGGTA

Product: glutamate synthase large subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSAPLYLGDMSYGALSGNPNIIIARAADLTGTLAGTGEGGLHPEVAKSKRIFVQWASARFGVDFDVLMHGAGIVIKIGQG
AKPGIGGHLPGSKVTEPISLTRRIPVGIDAISPAPHHDIYSIEDLGQRIEALKEATGKPVFVKVAATNYIPYIVSGIARM
GADGVIIDGHGAGTGATPIVIRDNVGIPIELAVASADKVLREQGMRDNFYIIAAGRVADATDAAKLIALGADVVSVGTGA
LIAMGCVMVHKCHIGSCPTALTNKIDGSRMVDIDFGLKVLVNYIHGFSLELANILDNLGLSSIDELKGRRDLLVGKGLSR
ETLSVLGIEGEEEELPPKLGELWSRRRKVYLHELINKGDPVITSMGSTAPPDVEKPARIVDWLRSDGAQVTRPSIDPYRE
DIDTSFYLAGGRIYLSLPVIFDIIDAPEDERNALQWASLALSSAVFTDVTPRYYEDISISHDGKGIIKWSKNYESGSYIL
LPSNEEALEEVVELKGIPGFIIDEDLGNEDLEVVISEIDTKLKRMGIRKKFDLIAKSSRIRDSGDVFKFVALGADSVIIS
YKVFEVALGEGSRSDLKSKAFNLISGFKKEIALLAGAAGVYSVQSTLTGNRELLRAINLNSYLLQKLRVKVAGSL

Sequences:

>Translated_635_residues
MSAPLYLGDMSYGALSGNPNIIIARAADLTGTLAGTGEGGLHPEVAKSKRIFVQWASARFGVDFDVLMHGAGIVIKIGQG
AKPGIGGHLPGSKVTEPISLTRRIPVGIDAISPAPHHDIYSIEDLGQRIEALKEATGKPVFVKVAATNYIPYIVSGIARM
GADGVIIDGHGAGTGATPIVIRDNVGIPIELAVASADKVLREQGMRDNFYIIAAGRVADATDAAKLIALGADVVSVGTGA
LIAMGCVMVHKCHIGSCPTALTNKIDGSRMVDIDFGLKVLVNYIHGFSLELANILDNLGLSSIDELKGRRDLLVGKGLSR
ETLSVLGIEGEEEELPPKLGELWSRRRKVYLHELINKGDPVITSMGSTAPPDVEKPARIVDWLRSDGAQVTRPSIDPYRE
DIDTSFYLAGGRIYLSLPVIFDIIDAPEDERNALQWASLALSSAVFTDVTPRYYEDISISHDGKGIIKWSKNYESGSYIL
LPSNEEALEEVVELKGIPGFIIDEDLGNEDLEVVISEIDTKLKRMGIRKKFDLIAKSSRIRDSGDVFKFVALGADSVIIS
YKVFEVALGEGSRSDLKSKAFNLISGFKKEIALLAGAAGVYSVQSTLTGNRELLRAINLNSYLLQKLRVKVAGSL
>Mature_634_residues
SAPLYLGDMSYGALSGNPNIIIARAADLTGTLAGTGEGGLHPEVAKSKRIFVQWASARFGVDFDVLMHGAGIVIKIGQGA
KPGIGGHLPGSKVTEPISLTRRIPVGIDAISPAPHHDIYSIEDLGQRIEALKEATGKPVFVKVAATNYIPYIVSGIARMG
ADGVIIDGHGAGTGATPIVIRDNVGIPIELAVASADKVLREQGMRDNFYIIAAGRVADATDAAKLIALGADVVSVGTGAL
IAMGCVMVHKCHIGSCPTALTNKIDGSRMVDIDFGLKVLVNYIHGFSLELANILDNLGLSSIDELKGRRDLLVGKGLSRE
TLSVLGIEGEEEELPPKLGELWSRRRKVYLHELINKGDPVITSMGSTAPPDVEKPARIVDWLRSDGAQVTRPSIDPYRED
IDTSFYLAGGRIYLSLPVIFDIIDAPEDERNALQWASLALSSAVFTDVTPRYYEDISISHDGKGIIKWSKNYESGSYILL
PSNEEALEEVVELKGIPGFIIDEDLGNEDLEVVISEIDTKLKRMGIRKKFDLIAKSSRIRDSGDVFKFVALGADSVIISY
KVFEVALGEGSRSDLKSKAFNLISGFKKEIALLAGAAGVYSVQSTLTGNRELLRAINLNSYLLQKLRVKVAGSL

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=308, Percent_Identity=37.012987012987, Blast_Score=161, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17570289, Length=315, Percent_Identity=37.4603174603175, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6320030, Length=314, Percent_Identity=35.6687898089172, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574881, Length=314, Percent_Identity=35.6687898089172, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24665539, Length=314, Percent_Identity=35.6687898089172, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013785
- InterPro:   IPR002932 [H]

Pfam domain/function: PF01645 Glu_synthase [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 68140; Mature: 68009

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPLYLGDMSYGALSGNPNIIIARAADLTGTLAGTGEGGLHPEVAKSKRIFVQWASARF
CCCCEEECCCCCCEECCCCCEEEEEECCCCEEEECCCCCCCCCHHHCCCEEEEEEECCCC
GVDFDVLMHGAGIVIKIGQGAKPGIGGHLPGSKVTEPISLTRRIPVGIDAISPAPHHDIY
CCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCE
SIEDLGQRIEALKEATGKPVFVKVAATNYIPYIVSGIARMGADGVIIDGHGAGTGATPIV
EHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCEEE
IRDNVGIPIELAVASADKVLREQGMRDNFYIIAAGRVADATDAAKLIALGADVVSVGTGA
EECCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCHH
LIAMGCVMVHKCHIGSCPTALTNKIDGSRMVDIDFGLKVLVNYIHGFSLELANILDNLGL
HHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCC
SSIDELKGRRDLLVGKGLSRETLSVLGIEGEEEELPPKLGELWSRRRKVYLHELINKGDP
CCHHHHCCCHHEEECCCCCCCHHEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
VITSMGSTAPPDVEKPARIVDWLRSDGAQVTRPSIDPYREDIDTSFYLAGGRIYLSLPVI
EEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHCCCEEEEECCEEEEECCCH
FDIIDAPEDERNALQWASLALSSAVFTDVTPRYYEDISISHDGKGIIKWSKNYESGSYIL
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCEEECCCCCEEEEECCCCCCCCEEE
LPSNEEALEEVVELKGIPGFIIDEDLGNEDLEVVISEIDTKLKRMGIRKKFDLIAKSSRI
EECCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
RDSGDVFKFVALGADSVIISYKVFEVALGEGSRSDLKSKAFNLISGFKKEIALLAGAAGV
CCCCCEEEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YSVQSTLTGNRELLRAINLNSYLLQKLRVKVAGSL
HHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAPLYLGDMSYGALSGNPNIIIARAADLTGTLAGTGEGGLHPEVAKSKRIFVQWASARF
CCCEEECCCCCCEECCCCCEEEEEECCCCEEEECCCCCCCCCHHHCCCEEEEEEECCCC
GVDFDVLMHGAGIVIKIGQGAKPGIGGHLPGSKVTEPISLTRRIPVGIDAISPAPHHDIY
CCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCE
SIEDLGQRIEALKEATGKPVFVKVAATNYIPYIVSGIARMGADGVIIDGHGAGTGATPIV
EHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCEEE
IRDNVGIPIELAVASADKVLREQGMRDNFYIIAAGRVADATDAAKLIALGADVVSVGTGA
EECCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCHH
LIAMGCVMVHKCHIGSCPTALTNKIDGSRMVDIDFGLKVLVNYIHGFSLELANILDNLGL
HHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCC
SSIDELKGRRDLLVGKGLSRETLSVLGIEGEEEELPPKLGELWSRRRKVYLHELINKGDP
CCHHHHCCCHHEEECCCCCCCHHEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
VITSMGSTAPPDVEKPARIVDWLRSDGAQVTRPSIDPYREDIDTSFYLAGGRIYLSLPVI
EEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHCCCEEEEECCEEEEECCCH
FDIIDAPEDERNALQWASLALSSAVFTDVTPRYYEDISISHDGKGIIKWSKNYESGSYIL
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCEEECCCCCEEEEECCCCCCCCEEE
LPSNEEALEEVVELKGIPGFIIDEDLGNEDLEVVISEIDTKLKRMGIRKKFDLIAKSSRI
EECCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
RDSGDVFKFVALGADSVIISYKVFEVALGEGSRSDLKSKAFNLISGFKKEIALLAGAAGV
CCCCCEEEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YSVQSTLTGNRELLRAINLNSYLLQKLRVKVAGSL
HHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]