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The map label for this gene is ppnK

Identifier: 15922463

GI number: 15922463

Start: 2138024

End: 2138770

Strand: Direct

Name: ppnK

Synonym: ST2136

Alternate gene names: 15922463

Gene position: 2138024-2138770 (Clockwise)

Preceding gene: 15922461

Following gene: 15922464

Centisome position: 79.34

GC content: 31.46

Gene sequence:

>747_bases
ATGAAATTGAAAATATTTACTAAAAACTCCCCTGACGCAATTGAGTTTAGTAAATACGTTAAAAATTTGGCTGAAAACTT
GGGTTTTAAGATAACTGAAAATGACCCAGATGTGGTTTTAGTAATAGGTGGCGATGGAACCTTATTAAGAGCAGTAAAAG
ATGGCATACCAATCTTAGGAGTGAAATTTGGACGTCGCTCAGCCTTACTAGATATAAGACCAGAAAACATTAAAGAAGCT
CTTGAACTATTACAGAAAAATAAATATACAATAGAAGAATATCCTATGCTTGAGGCTAAAAGCAAAAATATAAACACAAT
TGCTTTTAATGAAATAGCTATTTTATTCAACAACCCGGAGACAGTATATGGTAGTGTTAATATAAAAGAAAGAAAAATTC
TCTTTGAAGGAGATGGAGTACTTATAGCTACACCACAAGGTAGTTGGGCATGGAGCTATTCAGCAACTAGAGTCTTACTC
CATAAAGATATTAATGGAATTGAAATAACGTTCATAAACCCTATTATTCCAAACATAAAAGCTCTAATAATCCCTCAGAC
AGAGACAATACTTGTGAAATTGGAAGATAAAGGAAGAACACAAAATGTCAGAGTTATTAGTGACGGAGAAATTGTAGGAA
ATTTAATAAGTAAAGAAGACGAGGAATTAACTATAACTCTCTCTAAAAGAAAAGCAAAAATATTAAGGTTTTTTAACTTA
ATTGAATTTGATGGACTATTCACATAA

Upstream 100 bases:

>100_bases
TAAGATTATTGAACTATATTGGGGAAATAGAACTAATTAATGAAAGTAAAATATTTACCTTATCTGTAACTATTTTAACA
GAATAGAGGAGAATAATTTA

Downstream 100 bases:

>100_bases
AATTGTTTTTGATACTGGGGCATTTTTAGCTGGTCTGCAAAACTACTATGAAAAAATATACACCAATAGTCTTGTTATAA
ATGAGATAAAAGATAAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKLKIFTKNSPDAIEFSKYVKNLAENLGFKITENDPDVVLVIGGDGTLLRAVKDGIPILGVKFGRRSALLDIRPENIKEA
LELLQKNKYTIEEYPMLEAKSKNINTIAFNEIAILFNNPETVYGSVNIKERKILFEGDGVLIATPQGSWAWSYSATRVLL
HKDINGIEITFINPIIPNIKALIIPQTETILVKLEDKGRTQNVRVISDGEIVGNLISKEDEELTITLSKRKAKILRFFNL
IEFDGLFT

Sequences:

>Translated_248_residues
MKLKIFTKNSPDAIEFSKYVKNLAENLGFKITENDPDVVLVIGGDGTLLRAVKDGIPILGVKFGRRSALLDIRPENIKEA
LELLQKNKYTIEEYPMLEAKSKNINTIAFNEIAILFNNPETVYGSVNIKERKILFEGDGVLIATPQGSWAWSYSATRVLL
HKDINGIEITFINPIIPNIKALIIPQTETILVKLEDKGRTQNVRVISDGEIVGNLISKEDEELTITLSKRKAKILRFFNL
IEFDGLFT
>Mature_248_residues
MKLKIFTKNSPDAIEFSKYVKNLAENLGFKITENDPDVVLVIGGDGTLLRAVKDGIPILGVKFGRRSALLDIRPENIKEA
LELLQKNKYTIEEYPMLEAKSKNINTIAFNEIAILFNNPETVYGSVNIKERKILFEGDGVLIATPQGSWAWSYSATRVLL
HKDINGIEITFINPIIPNIKALIIPQTETILVKLEDKGRTQNVRVISDGEIVGNLISKEDEELTITLSKRKAKILRFFNL
IEFDGLFT

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Escherichia coli, GI1788968, Length=199, Percent_Identity=27.1356783919598, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_SULTO (Q96YN6)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378132.1
- ProteinModelPortal:   Q96YN6
- SMR:   Q96YN6
- GeneID:   1460209
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2136
- NMPDR:   fig|273063.1.peg.2300
- HOGENOM:   HBG553814
- OMA:   KITENDP
- ProtClustDB:   CLSK803255
- BioCyc:   STOK273063:ST2136-MONOMER
- BRENDA:   2.7.1.23
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 27888; Mature: 27888

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKIFTKNSPDAIEFSKYVKNLAENLGFKITENDPDVVLVIGGDGTLLRAVKDGIPILG
CEEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEEEHHCCCCEEE
VKFGRRSALLDIRPENIKEALELLQKNKYTIEEYPMLEAKSKNINTIAFNEIAILFNNPE
EEECCCEEEEEECCHHHHHHHHHHHCCCCEEHHCCCEECCCCCCEEEEEEEEEEEECCCC
TVYGSVNIKERKILFEGDGVLIATPQGSWAWSYSATRVLLHKDINGIEITFINPIIPNIK
EEEEEEEEEEEEEEEECCCEEEECCCCCEEEECCCEEEEEECCCCCEEEEEECCCCCCCE
ALIIPQTETILVKLEDKGRTQNVRVISDGEIVGNLISKEDEELTITLSKRKAKILRFFNL
EEEEECCEEEEEEECCCCCCCEEEEEECCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
IEFDGLFT
HCCCCCCC
>Mature Secondary Structure
MKLKIFTKNSPDAIEFSKYVKNLAENLGFKITENDPDVVLVIGGDGTLLRAVKDGIPILG
CEEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEEEHHCCCCEEE
VKFGRRSALLDIRPENIKEALELLQKNKYTIEEYPMLEAKSKNINTIAFNEIAILFNNPE
EEECCCEEEEEECCHHHHHHHHHHHCCCCEEHHCCCEECCCCCCEEEEEEEEEEEECCCC
TVYGSVNIKERKILFEGDGVLIATPQGSWAWSYSATRVLLHKDINGIEITFINPIIPNIK
EEEEEEEEEEEEEEEECCCEEEECCCCCEEEECCCEEEEEECCCCCEEEEEECCCCCCCE
ALIIPQTETILVKLEDKGRTQNVRVISDGEIVGNLISKEDEELTITLSKRKAKILRFFNL
EEEEECCEEEEEEECCCCCCCEEEEEECCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
IEFDGLFT
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479