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The map label for this gene is 15921990

Identifier: 15921990

GI number: 15921990

Start: 1686406

End: 1688331

Strand: Reverse

Name: 15921990

Synonym: ST1686

Alternate gene names: NA

Gene position: 1688331-1686406 (Counterclockwise)

Preceding gene: 15921991

Following gene: 15921989

Centisome position: 62.65

GC content: 37.85

Gene sequence:

>1926_bases
ATGCTTCTCGCGGTCGACATAGGTGGTACATTTACAGATATAATAGGAGTGAAAGATGACGGAGAAATTGTTTTCTACAA
AGGTTTATCAACACCAAAAAATCCAGAAAATGGAGTGAAAGAAGGTATTCAAAAATTAGGAATAAGTGTGGACACACTGA
TACATGCTACAACGATTGCAACAAACTCTCTTCTTGGACAAGTCAATTTAGAGTTACCTAAAACAGCATTAATCACTACT
AAGGGTTTTTCTGACATAATTGAGATTGGAAGACAAAACAGACCTGAACTCTATAATTTGTTCTTTCAAAAACCTAAACC
ATTGGTTCCTAAGGAGTTGAGATTTGAAGTTGACGAAAGGATTAATTCAAGAGGCGAAGTTTTAAAGCCACTCAATACTA
AGGAGATAGAAGAAATAGCAAAAAGGATCAATGTTGAGGCAGTTGCAGTAGTATTTTTGCATTCTTACTTAAATCCCACA
CACGAGAAGGTTGCTAAAGAAATACTTTCAAGATATGTAAAGTATGTTTCAGCATCTTATGAGGTTTCCCCAGAACAAAG
AGAGTATGAAAGAACAACAACGACAGTAATTAATGTAATGTTAAAGCCTCTTATAAGTAAGTACATAGAATCTTTGTCGA
AGGAAATAAAACCTAAGGAATTCTTTATAATGGCAAGTTCTGGTGGATTAATTGATGCTGATGAGGCTATTGAGAGACCA
GTACAATTAATCGAATCTGGACCAGCGGCTGGAGTTGTTGGGGTTAAATACTTTGCTGACGAGATGGGGATAAAAAATGC
CATAAGTTTTGATATGGGTGGAACTACAGCTAAAGCTGGTTCAATTGTTAATGGTGAAATTGAGATAACTAGTGAATATG
AGGTTGGTGGCAGGACTCATCACGGTAGAATAATAAAAGGCTCCGGCTATCCAGTTAGGTTTCCTTTCATTGATTTGGCT
GAAGTTTCTGCCGGTGGTGGAACAGTAATTTGGTTAGATGAGGCTGGGGGACTAAATGTTGGTCCTTTAAGTGCTGGTGC
TGATCCGGGTCCTATGTGCTATAATAAGGGTGGTAATTTGCCAACGTTAACTGACGCAAATCTCGTTTTAGGAAGAATTG
GAGAGGAGTTATTAAGCGGTGATATGAAACTGAATAAGGAACTGGCAATAAAAGGACTTGAAAAGTTAGGTGATCCTATA
CAAATTGCAAAGGAAGCAATAAGGCTAGCTACTTTAGAAATGGCTAGGGCAATAAGGTTGGTAACAGTCGAAAGGGGTTT
AGACCCTTCAGAATTCGCACTTTTCTCTTTTGGCGGTGCTGGACCGCAGTTTGCATTAGGCATAGCTGAAGAGCTTGGTA
TTAAGAGGGTTTTAGTTCCAGTCTATCCCGGATTGTTTAGTGCCCTATCTATGTTATTAGCTGATATTAAGATAGAAATT
AGAAGGGCTTATCCCAAGGACGTTAACTTAGAATTCAGAGAACTGGAAGAGGAATTGAGAAGGAAAATGTCCAGTATTGA
CTACTTTTTAAGGTATGCTGATGTTAGATATAAGGGTCAAGGATGGGAATTAACTGTACCCGCTGATGGTGATATAAGAA
GAAATTTTGAGGAGAGGCATAGAACTGCGTACGGTTTTACTTTACCCTATGATATCGAGATTGTGAATATAAGAGTGTTT
GCTGTTAAGAGGATTAAGAAGCCTAAGATAACGTTAAAGATCTCAGATAACGTTAAAGTAAAGGCGAGGAAAGTTTACTT
TGATGATTGGGTTAATGCTAAAGTCTTCATCAGAGAGACTTTGCCAATAGGCTTTAGAGATAGAGGTCCGGCAATCATAG
AAGAATACAGTGCAACAACATTAATTCCAGATGGTTGGAGTTTTACTATTCTCCCTAATTATTTCATAGAATTAACGAGG
GAGTAA

Upstream 100 bases:

>100_bases
TTACTGTAATGACATAGAATTGTCCCTTTTCCGATAACTAATTTTAAGTATTCACTCAGAAAAGGCAAAAAATTTTATAT
AGCTAAATATAGAATCTTAT

Downstream 100 bases:

>100_bases
AAATGGTTAGTTGGGAAGTTATAAATAAAGCTACAATATTCATTGCAGAAGAAATGGGAGTTATGTTAAAGAAATCTGCC
TTATCACCAAATATAAGGGA

Product: hydantoin utilization protein

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MLLAVDIGGTFTDIIGVKDDGEIVFYKGLSTPKNPENGVKEGIQKLGISVDTLIHATTIATNSLLGQVNLELPKTALITT
KGFSDIIEIGRQNRPELYNLFFQKPKPLVPKELRFEVDERINSRGEVLKPLNTKEIEEIAKRINVEAVAVVFLHSYLNPT
HEKVAKEILSRYVKYVSASYEVSPEQREYERTTTTVINVMLKPLISKYIESLSKEIKPKEFFIMASSGGLIDADEAIERP
VQLIESGPAAGVVGVKYFADEMGIKNAISFDMGGTTAKAGSIVNGEIEITSEYEVGGRTHHGRIIKGSGYPVRFPFIDLA
EVSAGGGTVIWLDEAGGLNVGPLSAGADPGPMCYNKGGNLPTLTDANLVLGRIGEELLSGDMKLNKELAIKGLEKLGDPI
QIAKEAIRLATLEMARAIRLVTVERGLDPSEFALFSFGGAGPQFALGIAEELGIKRVLVPVYPGLFSALSMLLADIKIEI
RRAYPKDVNLEFRELEEELRRKMSSIDYFLRYADVRYKGQGWELTVPADGDIRRNFEERHRTAYGFTLPYDIEIVNIRVF
AVKRIKKPKITLKISDNVKVKARKVYFDDWVNAKVFIRETLPIGFRDRGPAIIEEYSATTLIPDGWSFTILPNYFIELTR
E

Sequences:

>Translated_641_residues
MLLAVDIGGTFTDIIGVKDDGEIVFYKGLSTPKNPENGVKEGIQKLGISVDTLIHATTIATNSLLGQVNLELPKTALITT
KGFSDIIEIGRQNRPELYNLFFQKPKPLVPKELRFEVDERINSRGEVLKPLNTKEIEEIAKRINVEAVAVVFLHSYLNPT
HEKVAKEILSRYVKYVSASYEVSPEQREYERTTTTVINVMLKPLISKYIESLSKEIKPKEFFIMASSGGLIDADEAIERP
VQLIESGPAAGVVGVKYFADEMGIKNAISFDMGGTTAKAGSIVNGEIEITSEYEVGGRTHHGRIIKGSGYPVRFPFIDLA
EVSAGGGTVIWLDEAGGLNVGPLSAGADPGPMCYNKGGNLPTLTDANLVLGRIGEELLSGDMKLNKELAIKGLEKLGDPI
QIAKEAIRLATLEMARAIRLVTVERGLDPSEFALFSFGGAGPQFALGIAEELGIKRVLVPVYPGLFSALSMLLADIKIEI
RRAYPKDVNLEFRELEEELRRKMSSIDYFLRYADVRYKGQGWELTVPADGDIRRNFEERHRTAYGFTLPYDIEIVNIRVF
AVKRIKKPKITLKISDNVKVKARKVYFDDWVNAKVFIRETLPIGFRDRGPAIIEEYSATTLIPDGWSFTILPNYFIELTR
E
>Mature_641_residues
MLLAVDIGGTFTDIIGVKDDGEIVFYKGLSTPKNPENGVKEGIQKLGISVDTLIHATTIATNSLLGQVNLELPKTALITT
KGFSDIIEIGRQNRPELYNLFFQKPKPLVPKELRFEVDERINSRGEVLKPLNTKEIEEIAKRINVEAVAVVFLHSYLNPT
HEKVAKEILSRYVKYVSASYEVSPEQREYERTTTTVINVMLKPLISKYIESLSKEIKPKEFFIMASSGGLIDADEAIERP
VQLIESGPAAGVVGVKYFADEMGIKNAISFDMGGTTAKAGSIVNGEIEITSEYEVGGRTHHGRIIKGSGYPVRFPFIDLA
EVSAGGGTVIWLDEAGGLNVGPLSAGADPGPMCYNKGGNLPTLTDANLVLGRIGEELLSGDMKLNKELAIKGLEKLGDPI
QIAKEAIRLATLEMARAIRLVTVERGLDPSEFALFSFGGAGPQFALGIAEELGIKRVLVPVYPGLFSALSMLLADIKIEI
RRAYPKDVNLEFRELEEELRRKMSSIDYFLRYADVRYKGQGWELTVPADGDIRRNFEERHRTAYGFTLPYDIEIVNIRVF
AVKRIKKPKITLKISDNVKVKARKVYFDDWVNAKVFIRETLPIGFRDRGPAIIEEYSATTLIPDGWSFTILPNYFIELTR
E

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=734, Percent_Identity=30.2452316076294, Blast_Score=202, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI133901900, Length=719, Percent_Identity=27.3991655076495, Blast_Score=190, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322634, Length=752, Percent_Identity=30.4521276595745, Blast_Score=241, Evalue=3e-64,
Organism=Drosophila melanogaster, GI45550492, Length=725, Percent_Identity=29.2413793103448, Blast_Score=224, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71167; Mature: 71167

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAVDIGGTFTDIIGVKDDGEIVFYKGLSTPKNPENGVKEGIQKLGISVDTLIHATTIA
CEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
TNSLLGQVNLELPKTALITTKGFSDIIEIGRQNRPELYNLFFQKPKPLVPKELRFEVDER
HHHHEEEEEECCCCEEEEEECCHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
INSRGEVLKPLNTKEIEEIAKRINVEAVAVVFLHSYLNPTHEKVAKEILSRYVKYVSASY
CCCCCCEECCCCHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
EVSPEQREYERTTTTVINVMLKPLISKYIESLSKEIKPKEFFIMASSGGLIDADEAIERP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHH
VQLIESGPAAGVVGVKYFADEMGIKNAISFDMGGTTAKAGSIVNGEIEITSEYEVGGRTH
HHHHHCCCCCCEEHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECEEEEEEEEECCCCCC
HGRIIKGSGYPVRFPFIDLAEVSAGGGTVIWLDEAGGLNVGPLSAGADPGPMCYNKGGNL
CCEEEECCCCEEEECCEEHEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCC
PTLTDANLVLGRIGEELLSGDMKLNKELAIKGLEKLGDPIQIAKEAIRLATLEMARAIRL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEE
VTVERGLDPSEFALFSFGGAGPQFALGIAEELGIKRVLVPVYPGLFSALSMLLADIKIEI
EEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEHHHCHHHHHHHHHHHHHHHEEE
RRAYPKDVNLEFRELEEELRRKMSSIDYFLRYADVRYKGQGWELTVPADGDIRRNFEERH
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCEEEEECCCCHHHCCHHHHC
RTAYGFTLPYDIEIVNIRVFAVKRIKKPKITLKISDNVKVKARKVYFDDWVNAKVFIRET
CEEECCCCCCEEEEEEEEEEEEECCCCCEEEEEECCCCEEEEEEEEECCCCCCEEEEEEE
LPIGFRDRGPAIIEEYSATTLIPDGWSFTILPNYFIELTRE
CCCCCCCCCCHHHHHCCCCEECCCCCEEEECCCEEEEEECC
>Mature Secondary Structure
MLLAVDIGGTFTDIIGVKDDGEIVFYKGLSTPKNPENGVKEGIQKLGISVDTLIHATTIA
CEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
TNSLLGQVNLELPKTALITTKGFSDIIEIGRQNRPELYNLFFQKPKPLVPKELRFEVDER
HHHHEEEEEECCCCEEEEEECCHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
INSRGEVLKPLNTKEIEEIAKRINVEAVAVVFLHSYLNPTHEKVAKEILSRYVKYVSASY
CCCCCCEECCCCHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
EVSPEQREYERTTTTVINVMLKPLISKYIESLSKEIKPKEFFIMASSGGLIDADEAIERP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHH
VQLIESGPAAGVVGVKYFADEMGIKNAISFDMGGTTAKAGSIVNGEIEITSEYEVGGRTH
HHHHHCCCCCCEEHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECEEEEEEEEECCCCCC
HGRIIKGSGYPVRFPFIDLAEVSAGGGTVIWLDEAGGLNVGPLSAGADPGPMCYNKGGNL
CCEEEECCCCEEEECCEEHEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCC
PTLTDANLVLGRIGEELLSGDMKLNKELAIKGLEKLGDPIQIAKEAIRLATLEMARAIRL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEE
VTVERGLDPSEFALFSFGGAGPQFALGIAEELGIKRVLVPVYPGLFSALSMLLADIKIEI
EEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEHHHCHHHHHHHHHHHHHHHEEE
RRAYPKDVNLEFRELEEELRRKMSSIDYFLRYADVRYKGQGWELTVPADGDIRRNFEERH
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCEEEEECCCCHHHCCHHHHC
RTAYGFTLPYDIEIVNIRVFAVKRIKKPKITLKISDNVKVKARKVYFDDWVNAKVFIRET
CEEECCCCCCEEEEEEEEEEEEECCCCCEEEEEECCCCEEEEEEEEECCCCCCEEEEEEE
LPIGFRDRGPAIIEEYSATTLIPDGWSFTILPNYFIELTRE
CCCCCCCCCCHHHHHCCCCEECCCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]