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The map label for this gene is abfD [H]

Identifier: 15921962

GI number: 15921962

Start: 1656186

End: 1657694

Strand: Direct

Name: abfD [H]

Synonym: ST1659

Alternate gene names: 15921962

Gene position: 1656186-1657694 (Clockwise)

Preceding gene: 15921960

Following gene: 15921963

Centisome position: 61.46

GC content: 36.65

Gene sequence:

>1509_bases
ATGGCAATTAGAACTGGAGAGCAATATTTAGATTCTATAAAAATTAGAAATAAGGCTGAAATTTACGTAATGGGAAAAGA
AGTAAAGGATGTAACCACTCATCCCTTCTTGAAACCTTCTGTAATGGCATTTAAGGCAACATTTGATGCTGCTTGGGAAG
AGGACACAAAAGAATTAGCCAGAGCATGGAGTCCTTTCATAAATGAAGAAGTGAATAGATTTAATCACATACACAGGTCA
CCAGAAGACTTAGCTGCTAAAGTGAAATTACTGAGAAAATTAAGCCATAAGACCGGTGCATGTTTCCAAAGATGTGTAGG
ATGGGACGCTCTGAACACTTTGTGGATTATGACGAATATAATGGCTCAAAAAGGTAAAAAAGAATATAAGGATAGATTTG
TCGAATACTTAAGTTACGTCCAAAAGAAGGATTTAGCATTAGCTGGTGCTATGACAGATGCAAAAGGTGTAAGAACATTA
AAACCGCATCAACAACCAAATAAGAACGCTTATGTTAGAATTGAGGAAGTTACCAAAGACGGTATTTATGTTTCTGGTGC
AAAGGCAAATATTACTGGTGTAGCTGCAACAGAAGAAATTGTGGTTTTACCTACTAGGGCTATGGGGCCAGAAGATAAAG
ATTATGCTGTTGCATTTTCAATACCGACAGATACTGAGGGTATAAAAATTATAGTTGGTAGACAATTAAATGATGCTAGA
AGATTAGAAGGTGGTGACATAGATGCTTTACCGTACTTCTATAACCACGAGGGTTTAGTAATCTTTGACCATGTTTTTGT
ACCAATGGATAGAGTATTCTTAATGGGAGAATACGAGTTTACTTCACAATTAGTTGAAGTATTCTCAGCATATCATAGAC
AAGGATATGGTGGTTGCAAGGCTGGTTTAGGAGATGTAATTATTGGTGCATCAATGAATTTAGCAAAACAATTAGGAGTA
GAAAAAGCTTCACATGTACAAGAAAAACTAACGGAAATGATATTCTTAACTGAGACCATGTATTCTGCAGGAATTGCAGC
TAGTTTAAATGCAGTTAAGGTCTGCGATAATTGTTGGTGGGTTAATCCTATGCACGCTAATGTTACAAAACATTTAGTAG
CTAGATTTCCAGCCCAGATTTCTCAGTTATCTATCGATATTGCAGGTGGAATAATAGGTACTGCACCAAGTGAGTGGGAT
CTCAAGAATCCTAAATTAAGAGAATATATTGCCAAATACTTACAAGGTGTTGAGGGTTATACAGCTGAAGATAGATTAAG
AATGGTTAGATTACTGGAAAACGTTAGTCTGGGTGTTGCATTCCAAATTGAATCTGTACACGGTGCAGGAAGTCCAGCAG
CACAAAGAATAATGTTTAGTAGACTTTATGACTTAAACTATGCTGAGGAAGTCGCAAAGAGGTTAGCTGGGAAGAAGACT
GATTTACAGTGGAAACCTAAAGCAGAGCCTTGGAGAGAAAGTGAGACAGAAAAATTAGTAAAAAGTTAA

Upstream 100 bases:

>100_bases
TATGTCATGGTCAAAATTTTTTATAGTTACTAAAGGCTTTGAATATCGTTCATAAGAAACATATACAAAAGTTTAAAAAC
TTTAAAATATACATACTCCT

Downstream 100 bases:

>100_bases
TTTTTTATCTTTCACTCTAATATCCCCTTTTGTGTTCCTAAGAAAAACTAGTGGTCTTATAAAGGAACTTAACTCGCTTG
ACATTACATTACTTAATTTA

Product: 4-hydroxyphenylacetate 3-monooxygenase large subunit

Products: NA

Alternate protein names: 4-BUDH; Gamma-aminobutyrate metabolism dehydratase/isomerase [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MAIRTGEQYLDSIKIRNKAEIYVMGKEVKDVTTHPFLKPSVMAFKATFDAAWEEDTKELARAWSPFINEEVNRFNHIHRS
PEDLAAKVKLLRKLSHKTGACFQRCVGWDALNTLWIMTNIMAQKGKKEYKDRFVEYLSYVQKKDLALAGAMTDAKGVRTL
KPHQQPNKNAYVRIEEVTKDGIYVSGAKANITGVAATEEIVVLPTRAMGPEDKDYAVAFSIPTDTEGIKIIVGRQLNDAR
RLEGGDIDALPYFYNHEGLVIFDHVFVPMDRVFLMGEYEFTSQLVEVFSAYHRQGYGGCKAGLGDVIIGASMNLAKQLGV
EKASHVQEKLTEMIFLTETMYSAGIAASLNAVKVCDNCWWVNPMHANVTKHLVARFPAQISQLSIDIAGGIIGTAPSEWD
LKNPKLREYIAKYLQGVEGYTAEDRLRMVRLLENVSLGVAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLAGKKT
DLQWKPKAEPWRESETEKLVKS

Sequences:

>Translated_502_residues
MAIRTGEQYLDSIKIRNKAEIYVMGKEVKDVTTHPFLKPSVMAFKATFDAAWEEDTKELARAWSPFINEEVNRFNHIHRS
PEDLAAKVKLLRKLSHKTGACFQRCVGWDALNTLWIMTNIMAQKGKKEYKDRFVEYLSYVQKKDLALAGAMTDAKGVRTL
KPHQQPNKNAYVRIEEVTKDGIYVSGAKANITGVAATEEIVVLPTRAMGPEDKDYAVAFSIPTDTEGIKIIVGRQLNDAR
RLEGGDIDALPYFYNHEGLVIFDHVFVPMDRVFLMGEYEFTSQLVEVFSAYHRQGYGGCKAGLGDVIIGASMNLAKQLGV
EKASHVQEKLTEMIFLTETMYSAGIAASLNAVKVCDNCWWVNPMHANVTKHLVARFPAQISQLSIDIAGGIIGTAPSEWD
LKNPKLREYIAKYLQGVEGYTAEDRLRMVRLLENVSLGVAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLAGKKT
DLQWKPKAEPWRESETEKLVKS
>Mature_501_residues
AIRTGEQYLDSIKIRNKAEIYVMGKEVKDVTTHPFLKPSVMAFKATFDAAWEEDTKELARAWSPFINEEVNRFNHIHRSP
EDLAAKVKLLRKLSHKTGACFQRCVGWDALNTLWIMTNIMAQKGKKEYKDRFVEYLSYVQKKDLALAGAMTDAKGVRTLK
PHQQPNKNAYVRIEEVTKDGIYVSGAKANITGVAATEEIVVLPTRAMGPEDKDYAVAFSIPTDTEGIKIIVGRQLNDARR
LEGGDIDALPYFYNHEGLVIFDHVFVPMDRVFLMGEYEFTSQLVEVFSAYHRQGYGGCKAGLGDVIIGASMNLAKQLGVE
KASHVQEKLTEMIFLTETMYSAGIAASLNAVKVCDNCWWVNPMHANVTKHLVARFPAQISQLSIDIAGGIIGTAPSEWDL
KNPKLREYIAKYLQGVEGYTAEDRLRMVRLLENVSLGVAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLAGKKTD
LQWKPKAEPWRESETEKLVKS

Specific function: Catalyzes the reversible conversion of 4-hydroxybutyryl- CoA to crotonyl-CoA. The mechanism of the reaction seems to go through three steps:(1) the FAD-dependent oxidation of 4- hydroxybutyryl-CoA to 4-hydroxycrotonyl-CoA; (2) the hydroxyl group is substi

COG id: COG2368

COG function: function code Q; Aromatic ring hydroxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100
- InterPro:   IPR004925 [H]

Pfam domain/function: PF03241 HpaB [H]

EC number: =4.2.1.120; =5.3.3.3 [H]

Molecular weight: Translated: 56365; Mature: 56234

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRTGEQYLDSIKIRNKAEIYVMGKEVKDVTTHPFLKPSVMAFKATFDAAWEEDTKELA
CCCCCCHHHHHHHHCCCCEEEEEECCCHHHCCCCCCCCCCHHEEEHHHHHHHHHHHHHHH
RAWSPFINEEVNRFNHIHRSPEDLAAKVKLLRKLSHKTGACFQRCVGWDALNTLWIMTNI
HHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHH
MAQKGKKEYKDRFVEYLSYVQKKDLALAGAMTDAKGVRTLKPHQQPNKNAYVRIEEVTKD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
GIYVSGAKANITGVAATEEIVVLPTRAMGPEDKDYAVAFSIPTDTEGIKIIVGRQLNDAR
CEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHH
RLEGGDIDALPYFYNHEGLVIFDHVFVPMDRVFLMGEYEFTSQLVEVFSAYHRQGYGGCK
HCCCCCCCCCCEEECCCCEEEEEEHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCC
AGLGDVIIGASMNLAKQLGVEKASHVQEKLTEMIFLTETMYSAGIAASLNAVKVCDNCWW
CCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCEE
VNPMHANVTKHLVARFPAQISQLSIDIAGGIIGTAPSEWDLKNPKLREYIAKYLQGVEGY
CCCHHHHHHHHHHHHHHHHHHHEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
TAEDRLRMVRLLENVSLGVAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLAGKKT
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
DLQWKPKAEPWRESETEKLVKS
CCCCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
AIRTGEQYLDSIKIRNKAEIYVMGKEVKDVTTHPFLKPSVMAFKATFDAAWEEDTKELA
CCCCCHHHHHHHHCCCCEEEEEECCCHHHCCCCCCCCCCHHEEEHHHHHHHHHHHHHHH
RAWSPFINEEVNRFNHIHRSPEDLAAKVKLLRKLSHKTGACFQRCVGWDALNTLWIMTNI
HHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHH
MAQKGKKEYKDRFVEYLSYVQKKDLALAGAMTDAKGVRTLKPHQQPNKNAYVRIEEVTKD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
GIYVSGAKANITGVAATEEIVVLPTRAMGPEDKDYAVAFSIPTDTEGIKIIVGRQLNDAR
CEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHH
RLEGGDIDALPYFYNHEGLVIFDHVFVPMDRVFLMGEYEFTSQLVEVFSAYHRQGYGGCK
HCCCCCCCCCCEEECCCCEEEEEEHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCC
AGLGDVIIGASMNLAKQLGVEKASHVQEKLTEMIFLTETMYSAGIAASLNAVKVCDNCWW
CCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCEE
VNPMHANVTKHLVARFPAQISQLSIDIAGGIIGTAPSEWDLKNPKLREYIAKYLQGVEGY
CCCHHHHHHHHHHHHHHHHHHHEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
TAEDRLRMVRLLENVSLGVAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLAGKKT
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
DLQWKPKAEPWRESETEKLVKS
CCCCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11041350; 8344309 [H]