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The map label for this gene is ubiB [C]

Identifier: 15921955

GI number: 15921955

Start: 1646394

End: 1647860

Strand: Direct

Name: ubiB [C]

Synonym: ST1652

Alternate gene names: 15921955

Gene position: 1646394-1647860 (Clockwise)

Preceding gene: 15921954

Following gene: 15921957

Centisome position: 61.1

GC content: 32.52

Gene sequence:

>1467_bases
ATGATTAGAGAGCTTCAAGTAATAATTAAATTAGCACCTAGAGTTCTGAAGCTTAGAGAATTTAGGCAGAGGGAATTTAA
GGGAGAAAAAATTGATGAAGAGGAAATGAGAAAAGAAGGAAGAAAATTACTTGAAGCGTTTATTTCTTTAGGACCAGCAT
TTATTAAATTAGGCCAAGTTCTTTCTGTTCATTCTGATGTTCTACCGGAACCTTATCTAAAGGAATTATCTAAATTACAA
GACGAAGTTCCTCCAGCACCATGGGAGGAAGTTGAACCTATACTTAGAGAAGATTTAGGGGAGAAGTTTAATGAATATGA
AATAGAGAAGAAACCAATATCTTCAGCAAGTATAGGTCAAGTTTATTTAGCAAAAGAAAAAAAGTCCGGCAAAATAGTAG
TGATTAAGGTAAATAGGCCTAGAATTAAGGAAATCGCAGAAAGAGATGTAAAAGTTATCCAGAATTTATTACCTTTAACA
AAGTATCTATTTGATGAGTCCTTTTATGAAAGTTTAAGGGCAATAGTGAATGACTTTAGTAAGAGAATATTTGAAGAAAT
GGATTTTACTAAAGAAGCATTCTACATGAAAAAAATTAAAGAGGAGCTTGAAGAATTTCCCGATGTTATTGTGCCAGAAT
CATATTATGCGACTAAACGAGTACTTATCATGGAATATTTAAAAGGGTATAAAGTCACTTCTCCAGAGGCTAAAAAGATT
GTAAAGCCCGATTATTTAGCATACAGGGTATTTAGAACTTTTATGTTATTATTATTAACGAAAGAGTATTTTCATGCTGA
TCCTCATCCTGGGAATTTAGCTGTTGATGAAAAAGGGAATTTAATACTTTACGATTTCGGAATGGTTGGAAGAATGGATA
AAGAGACAAGAAATAGACTTTTAAGAGCTTACGCTGCCCTAATAAGGCTAGACGCAATAGGTTTAGTAAAAGTCCTTGAA
GAATTAGGGGCTATTCAGCCTGAAGCAGATAGGGAAATATTAGCAAAAGGTATAGAGCTATTCTTAAAAACATTTGAGGG
AATTTCAGTAGAAACCCTAGAAGTAGAAACTTTCCTTAACGCGGCAAATGAAGTATTTTATCGTTTTCCACTAAAAATAC
CAGAAAAGTTAGCAATATATATAAGAATGACATCAGTACTTGGAGGTACTTGCACACAAATAGATCCAGATTTTAATTTC
TTTGTAAATTTACAGAAGTTAATTGAAGAAGAAGGACTTCAATGGAGTGCCATGTTTGATGATATCAGAAATACGATGGA
AGCAGCGATAAAAAAATTTAGATTATCCTTACTAGAAAAACCTGTAGTGCCCGCTAAGAAGAGTAATAGGGGTAGTATTA
TAGCCCCTATATTGGTTATTATAGCAATAATTTATTACTTAATGTCTCACGATGCTATTGTTTCAATATTAATAGGTATA
TTTGCATTAACTATAAATAGGGTTTAA

Upstream 100 bases:

>100_bases
ATGGAGCTATTTAAGTCCCTCGTTATTGCTTATCCTTTACAGAAGATTTAAGATAAGGCCTAAGCTAATAGTATAAAAGC
TATATTTTTTATTTCTATAT

Downstream 100 bases:

>100_bases
AAAAGAAAATTAAGTCATTCTATCTTTATAACAGATGTCCCAGCTATCGGTATCCTAATTGTTAGTACACCATTTTCATA
TTTCCCAGATATTTCAGCAT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MIRELQVIIKLAPRVLKLREFRQREFKGEKIDEEEMRKEGRKLLEAFISLGPAFIKLGQVLSVHSDVLPEPYLKELSKLQ
DEVPPAPWEEVEPILREDLGEKFNEYEIEKKPISSASIGQVYLAKEKKSGKIVVIKVNRPRIKEIAERDVKVIQNLLPLT
KYLFDESFYESLRAIVNDFSKRIFEEMDFTKEAFYMKKIKEELEEFPDVIVPESYYATKRVLIMEYLKGYKVTSPEAKKI
VKPDYLAYRVFRTFMLLLLTKEYFHADPHPGNLAVDEKGNLILYDFGMVGRMDKETRNRLLRAYAALIRLDAIGLVKVLE
ELGAIQPEADREILAKGIELFLKTFEGISVETLEVETFLNAANEVFYRFPLKIPEKLAIYIRMTSVLGGTCTQIDPDFNF
FVNLQKLIEEEGLQWSAMFDDIRNTMEAAIKKFRLSLLEKPVVPAKKSNRGSIIAPILVIIAIIYYLMSHDAIVSILIGI
FALTINRV

Sequences:

>Translated_488_residues
MIRELQVIIKLAPRVLKLREFRQREFKGEKIDEEEMRKEGRKLLEAFISLGPAFIKLGQVLSVHSDVLPEPYLKELSKLQ
DEVPPAPWEEVEPILREDLGEKFNEYEIEKKPISSASIGQVYLAKEKKSGKIVVIKVNRPRIKEIAERDVKVIQNLLPLT
KYLFDESFYESLRAIVNDFSKRIFEEMDFTKEAFYMKKIKEELEEFPDVIVPESYYATKRVLIMEYLKGYKVTSPEAKKI
VKPDYLAYRVFRTFMLLLLTKEYFHADPHPGNLAVDEKGNLILYDFGMVGRMDKETRNRLLRAYAALIRLDAIGLVKVLE
ELGAIQPEADREILAKGIELFLKTFEGISVETLEVETFLNAANEVFYRFPLKIPEKLAIYIRMTSVLGGTCTQIDPDFNF
FVNLQKLIEEEGLQWSAMFDDIRNTMEAAIKKFRLSLLEKPVVPAKKSNRGSIIAPILVIIAIIYYLMSHDAIVSILIGI
FALTINRV
>Mature_488_residues
MIRELQVIIKLAPRVLKLREFRQREFKGEKIDEEEMRKEGRKLLEAFISLGPAFIKLGQVLSVHSDVLPEPYLKELSKLQ
DEVPPAPWEEVEPILREDLGEKFNEYEIEKKPISSASIGQVYLAKEKKSGKIVVIKVNRPRIKEIAERDVKVIQNLLPLT
KYLFDESFYESLRAIVNDFSKRIFEEMDFTKEAFYMKKIKEELEEFPDVIVPESYYATKRVLIMEYLKGYKVTSPEAKKI
VKPDYLAYRVFRTFMLLLLTKEYFHADPHPGNLAVDEKGNLILYDFGMVGRMDKETRNRLLRAYAALIRLDAIGLVKVLE
ELGAIQPEADREILAKGIELFLKTFEGISVETLEVETFLNAANEVFYRFPLKIPEKLAIYIRMTSVLGGTCTQIDPDFNF
FVNLQKLIEEEGLQWSAMFDDIRNTMEAAIKKFRLSLLEKPVVPAKKSNRGSIIAPILVIIAIIYYLMSHDAIVSILIGI
FALTINRV

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=298, Percent_Identity=27.1812080536913, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI41393593, Length=281, Percent_Identity=29.1814946619217, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI217035081, Length=279, Percent_Identity=25.089605734767, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI34147522, Length=249, Percent_Identity=26.1044176706827, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI2367309, Length=385, Percent_Identity=27.5324675324675, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17559152, Length=299, Percent_Identity=28.4280936454849, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32565180, Length=286, Percent_Identity=25.8741258741259, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=287, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=255, Percent_Identity=27.4509803921569, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325148, Length=257, Percent_Identity=24.5136186770428, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24662575, Length=284, Percent_Identity=28.169014084507, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI22024280, Length=311, Percent_Identity=26.0450160771704, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI18859849, Length=294, Percent_Identity=25.1700680272109, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 56388; Mature: 56388

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRELQVIIKLAPRVLKLREFRQREFKGEKIDEEEMRKEGRKLLEAFISLGPAFIKLGQV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LSVHSDVLPEPYLKELSKLQDEVPPAPWEEVEPILREDLGEKFNEYEIEKKPISSASIGQ
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VYLAKEKKSGKIVVIKVNRPRIKEIAERDVKVIQNLLPLTKYLFDESFYESLRAIVNDFS
EEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIFEEMDFTKEAFYMKKIKEELEEFPDVIVPESYYATKRVLIMEYLKGYKVTSPEAKKI
HHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHC
VKPDYLAYRVFRTFMLLLLTKEYFHADPHPGNLAVDEKGNLILYDFGMVGRMDKETRNRL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHH
LRAYAALIRLDAIGLVKVLEELGAIQPEADREILAKGIELFLKTFEGISVETLEVETFLN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
AANEVFYRFPLKIPEKLAIYIRMTSVLGGTCTQIDPDFNFFVNLQKLIEEEGLQWSAMFD
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
DIRNTMEAAIKKFRLSLLEKPVVPAKKSNRGSIIAPILVIIAIIYYLMSHDAIVSILIGI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALTINRV
HHHHHCCC
>Mature Secondary Structure
MIRELQVIIKLAPRVLKLREFRQREFKGEKIDEEEMRKEGRKLLEAFISLGPAFIKLGQV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LSVHSDVLPEPYLKELSKLQDEVPPAPWEEVEPILREDLGEKFNEYEIEKKPISSASIGQ
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VYLAKEKKSGKIVVIKVNRPRIKEIAERDVKVIQNLLPLTKYLFDESFYESLRAIVNDFS
EEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIFEEMDFTKEAFYMKKIKEELEEFPDVIVPESYYATKRVLIMEYLKGYKVTSPEAKKI
HHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHC
VKPDYLAYRVFRTFMLLLLTKEYFHADPHPGNLAVDEKGNLILYDFGMVGRMDKETRNRL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHH
LRAYAALIRLDAIGLVKVLEELGAIQPEADREILAKGIELFLKTFEGISVETLEVETFLN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
AANEVFYRFPLKIPEKLAIYIRMTSVLGGTCTQIDPDFNFFVNLQKLIEEEGLQWSAMFD
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
DIRNTMEAAIKKFRLSLLEKPVVPAKKSNRGSIIAPILVIIAIIYYLMSHDAIVSILIGI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALTINRV
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]