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The map label for this gene is tmk

Identifier: 15921837

GI number: 15921837

Start: 1537017

End: 1537658

Strand: Reverse

Name: tmk

Synonym: ST1543

Alternate gene names: 15921837

Gene position: 1537658-1537017 (Counterclockwise)

Preceding gene: 15921838

Following gene: 15921836

Centisome position: 57.06

GC content: 33.8

Gene sequence:

>642_bases
ATGAAAAAGGGAGTTCTAATAGCTTTTGAAGGAATTGATGGATCTGGTAAATCAAGTCAGGCTACGTTACTTAAGGATTG
GATAGAATTAAAAAGAGATGTCTATCTAACTGAGTGGAACTCCTCAGACTGGATTCATGATATAATTAAAGAGGCAAAGA
AGAAAGATCTTCTTACCCCATTAACTTTTAGTCTAATACACGCTACTGATTTTTCTGACAGGTATGAAAGGTATATTTTA
CCAATGTTAAAGTCTGGTTTCATAGTTATTTCTGATAGGTACATTTACACAGCTTATGCTAGGGATAGCGTTAGGGGAGT
AGATATTGATTGGGTTAAGAAACTGTACTCATTTGCTATAAAACCGGATATTACTTTTTACATCAGAGTTTCACCAGATA
TAGCACTAGAGAGGATAAAGAAATCAAAAAGGAAAATAAAACCTCAAGAGGCTGGTGCTGATATATTTCCAGGATTATCA
CCAGAGGAGGGATTCCTGAAATACCAGGGACTAATTACTGAGGTTTATGATAAATTAGTTAAGGATGAGAATTTTATAGT
GATTGACGGAACTAAAACTCCGAAGGAAATACAAATTCAAATTAGAAAATTTGTAGGTGAGTTAATTGATAATAGCTTTT
GA

Upstream 100 bases:

>100_bases
ATATTAAATTTTTAAGTGAAAAACCGAGTAAAAAAGAGCTATCATCTTATGGAAATATAGTGAAAAACGCGGTTGAGAAA
TATGTTAATGGTGTTAGACT

Downstream 100 bases:

>100_bases
AGGAATTGAGGGATCTGGTAGGACAGCCCATTTAGAGGCTGTTAAACGTTACCTAGAAAAAGAAGGTTATGGTACAGTAA
CTTTTGGATTACAGATGTCA

Product: thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKKGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTPLTFSLIHATDFSDRYERYIL
PMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAIKPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLS
PEEGFLKYQGLITEVYDKLVKDENFIVIDGTKTPKEIQIQIRKFVGELIDNSF

Sequences:

>Translated_213_residues
MKKGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTPLTFSLIHATDFSDRYERYIL
PMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAIKPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLS
PEEGFLKYQGLITEVYDKLVKDENFIVIDGTKTPKEIQIQIRKFVGELIDNSF
>Mature_213_residues
MKKGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTPLTFSLIHATDFSDRYERYIL
PMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAIKPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLS
PEEGFLKYQGLITEVYDKLVKDENFIVIDGTKTPKEIQIQIRKFVGELIDNSF

Specific function: Unknown

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family

Homologues:

Organism=Drosophila melanogaster, GI28573735, Length=218, Percent_Identity=27.0642201834862, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KTHY2_SULTO (Q970Q8)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377506.1
- PDB:   2PLR
- PDBsum:   2PLR
- ProteinModelPortal:   Q970Q8
- SMR:   Q970Q8
- GeneID:   1459579
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1543
- NMPDR:   fig|273063.1.peg.1674
- HOGENOM:   HBG626009
- OMA:   TAYARDS
- ProtClustDB:   CLSK803042
- BioCyc:   STOK273063:ST1543-MONOMER
- BRENDA:   2.7.4.9
- HAMAP:   MF_00165
- InterPro:   IPR018094
- PANTHER:   PTHR10344
- TIGRFAMs:   TIGR00041

Pfam domain/function: PF02223 Thymidylate_kin

EC number: =2.7.4.9

Molecular weight: Translated: 24596; Mature: 24596

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS01331 THYMIDYLATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTP
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHCCCCH
LTFSLIHATDFSDRYERYILPMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAI
HHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHCC
KPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLSPEEGFLKYQGLITEVYDKLV
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KDENFIVIDGTKTPKEIQIQIRKFVGELIDNSF
CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTP
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHCCCCH
LTFSLIHATDFSDRYERYILPMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAI
HHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHCC
KPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLSPEEGFLKYQGLITEVYDKLV
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KDENFIVIDGTKTPKEIQIQIRKFVGELIDNSF
CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479