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The map label for this gene is rpiA [H]

Identifier: 15921570

GI number: 15921570

Start: 1304100

End: 1304759

Strand: Reverse

Name: rpiA [H]

Synonym: ST1302

Alternate gene names: 15921570

Gene position: 1304759-1304100 (Counterclockwise)

Preceding gene: 15921571

Following gene: 15921569

Centisome position: 48.42

GC content: 31.52

Gene sequence:

>660_bases
ATGGACCCAAAAGAAGTAGTAGCTCGCTTTATTGTTGATAAATTAAAGGAGCATAAACTAATAGGCTTAGGTACAGGTAA
AACAGTAAAGAAACTAATAGAAGTTTTAAGTGAAGAAGGTCTTCTAAAGGAAAAGATATTTGTGGCAAGTTCAATAGATA
CGGAGTTAGAGATTAGTAAGAGAGAAGGAATAGTGATCACCTTATATTCTGGTTTAAGACCTCAAGTATATATAGATAGT
TTTGATTTCGTAACTTCTGATAAGATTATGATTAAAGGTGGAGGAGCCGCTTTGCTTAGAGAAAAAATGTTATACACATT
CTCTAAGGAAAAAGTATTTATTGGTGAAGAGTTAAAACTTAAGGATTTAAAAGAGTATTCTGTTCCTGTTGAGGTTGTAC
CAGTAGGAGTAGCATACGTTATTTCAGCTCTTAAAGAAAGAGGCTATGAAGCAAAAATAAGAGAGGGAAATGGTAAAATT
GGTCCCATAATCTCAGATAATGGGAATATAATTTTAGATGTTATTGTAAAGAGGGAAAATTTATGTGATTTTGAAAGATT
GGTAAAAGAAATTCCTGCAATAATTGAAAGTGGTATATTTTGCAAAAAAGATTATGAAATTTACTTGGCTAACGAAAATG
GGAGGATTAGTATTTTGTGA

Upstream 100 bases:

>100_bases
AGCTCGGGCACCCCCGCTCTAGCTTATAAATTTTGTACAATAGCTTAAATAGGTTTTCTTCATCCTAAACCTTTTATTCA
ACATATCAATAGTTCTTCTC

Downstream 100 bases:

>100_bases
TTTTTTAGTGATCATACATGAATGAATGTGCCGTTATTAAATTATTTTATCTGAGGGGTAAGAAGTATCGTGATCTATAT
AGATTTATAGTGCTGACTAT

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MDPKEVVARFIVDKLKEHKLIGLGTGKTVKKLIEVLSEEGLLKEKIFVASSIDTELEISKREGIVITLYSGLRPQVYIDS
FDFVTSDKIMIKGGGAALLREKMLYTFSKEKVFIGEELKLKDLKEYSVPVEVVPVGVAYVISALKERGYEAKIREGNGKI
GPIISDNGNIILDVIVKRENLCDFERLVKEIPAIIESGIFCKKDYEIYLANENGRISIL

Sequences:

>Translated_219_residues
MDPKEVVARFIVDKLKEHKLIGLGTGKTVKKLIEVLSEEGLLKEKIFVASSIDTELEISKREGIVITLYSGLRPQVYIDS
FDFVTSDKIMIKGGGAALLREKMLYTFSKEKVFIGEELKLKDLKEYSVPVEVVPVGVAYVISALKERGYEAKIREGNGKI
GPIISDNGNIILDVIVKRENLCDFERLVKEIPAIIESGIFCKKDYEIYLANENGRISIL
>Mature_219_residues
MDPKEVVARFIVDKLKEHKLIGLGTGKTVKKLIEVLSEEGLLKEKIFVASSIDTELEISKREGIVITLYSGLRPQVYIDS
FDFVTSDKIMIKGGGAALLREKMLYTFSKEKVFIGEELKLKDLKEYSVPVEVVPVGVAYVISALKERGYEAKIREGNGKI
GPIISDNGNIILDVIVKRENLCDFERLVKEIPAIIESGIFCKKDYEIYLANENGRISIL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=231, Percent_Identity=25.1082251082251, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1789280, Length=210, Percent_Identity=30.952380952381, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17551758, Length=209, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324669, Length=246, Percent_Identity=27.2357723577236, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281364072, Length=219, Percent_Identity=31.9634703196347, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24541; Mature: 24541

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKEVVARFIVDKLKEHKLIGLGTGKTVKKLIEVLSEEGLLKEKIFVASSIDTELEISK
CCHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCCHHHHEEEEECCCCCEEEEC
REGIVITLYSGLRPQVYIDSFDFVTSDKIMIKGGGAALLREKMLYTFSKEKVFIGEELKL
CCCEEEEEECCCCCEEEEECCCCEECCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCH
KDLKEYSVPVEVVPVGVAYVISALKERGYEAKIREGNGKIGPIISDNGNIILDVIVKREN
HHHHHHCCCEEEEECCHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEEEEEECCC
LCDFERLVKEIPAIIESGIFCKKDYEIYLANENGRISIL
CCCHHHHHHHHHHHHHCCCEEEECCEEEEECCCCEEEEC
>Mature Secondary Structure
MDPKEVVARFIVDKLKEHKLIGLGTGKTVKKLIEVLSEEGLLKEKIFVASSIDTELEISK
CCHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCCHHHHEEEEECCCCCEEEEC
REGIVITLYSGLRPQVYIDSFDFVTSDKIMIKGGGAALLREKMLYTFSKEKVFIGEELKL
CCCEEEEEECCCCCEEEEECCCCEECCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCH
KDLKEYSVPVEVVPVGVAYVISALKERGYEAKIREGNGKIGPIISDNGNIILDVIVKREN
HHHHHHCCCEEEEECCHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEEEEEECCC
LCDFERLVKEIPAIIESGIFCKKDYEIYLANENGRISIL
CCCHHHHHHHHHHHHHCCCEEEECCEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA