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The map label for this gene is trpD

Identifier: 15921494

GI number: 15921494

Start: 1232065

End: 1233102

Strand: Reverse

Name: trpD

Synonym: ST1231

Alternate gene names: 15921494

Gene position: 1233102-1232065 (Counterclockwise)

Preceding gene: 15921495

Following gene: 15921493

Centisome position: 45.76

GC content: 33.72

Gene sequence:

>1038_bases
ATGAATACAGCTGAATTACTAAGAAAAATAATCAGAAGAGAAAATCTAACTGAAGATGAAGCAAGAAGTATAGCTAATAG
CGTAATGAAGGCAGAAGTACCAGAAATAGTTACTGCTGGATTTTTAGTAGGTTTAGCAACAAAGGGAGAAAGTGTTGAAG
AAATAACTGGGTTTGCAAAGGCAATGAGAGATAATGCTTTGCATATTAACTTTCCCTCAGCATTAGATACAGCTGGTACT
GGCGGTGATGGTTTAAATACACTAAATGTCAGTACAGCAGTAGCATTGCTGATAAGTCAAGTATACCCAGTAGCTAAACA
TGGTAATAGAGCTGTAAGTGGTAAGTCTGGTAGTGCTGATGTACTTGAAGCTCTTGGCTATAATATAATTGTGAAACCCG
AGCTAGCTGAGAAATTAATTAAAGAGTCTAAGTTTGTATTTCTATTTGCTCAACTTTATCATCCAGCTATGAAAAATGTA
GCTAATGTCAGAAAGACTTTAGGTGTTAGAACTATATTTAATGTACTAGGTCCTTTAACAAATCCAGCAAATGCAAGATA
TCAAATGATAGGCGTCTTCTCGAAAGAGTTTTTACCAAAACTCGCTGAAGCCGTAGTGCGTCTTGATTATGATAGAGTTA
TACTTTATAATGGTTTTCCATCTTTAGATGAGATTAGCACACAAGGAATTACGTATGTATATGAAATTGAAAAAGATAAA
ATAGTTAGTTATACTGTTTCTATTAACGACTTTGGACTTAAGGATGAGATCCCTGTATCTAAACTCACTGTTAACGATGC
TACTCATTCAGCATTAAGAATTCTAAAGGCATTTAAAGGAAAAGATGAAGAAGCTAGAAGATTTATAGGGATAAACACAG
CTATGGCTCTTTATTTAATTAGAAAAGTAAAAGACCTCAAAGATGGATATGAATACGCTTTACAGTTAATGGATTCTGGT
ATACCTCATGTAAGAAGTTTAATAGAGAAGAACGGTGATTTAAGTAACTTTAATAAGTTGGTGGAGAAAATTGATTAA

Upstream 100 bases:

>100_bases
GCTGATGGTGTAGCCATAGGTACAGCTTTCATAGAAGAAATAGAAAAAAATGGTATTCAATCAGCTTTACATTTAGTCAA
AACTATTAGAGGGATATTAG

Downstream 100 bases:

>100_bases
AATAAAATTTTGTGGTATATCTCACATTGAAGATGCTATCGTAGCCTCTAATTACGCTGATTTAATAGGCGTAGTTACTG
ATCCTATAAGTCCAAGATTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNTAELLRKIIRRENLTEDEARSIANSVMKAEVPEIVTAGFLVGLATKGESVEEITGFAKAMRDNALHINFPSALDTAGT
GGDGLNTLNVSTAVALLISQVYPVAKHGNRAVSGKSGSADVLEALGYNIIVKPELAEKLIKESKFVFLFAQLYHPAMKNV
ANVRKTLGVRTIFNVLGPLTNPANARYQMIGVFSKEFLPKLAEAVVRLDYDRVILYNGFPSLDEISTQGITYVYEIEKDK
IVSYTVSINDFGLKDEIPVSKLTVNDATHSALRILKAFKGKDEEARRFIGINTAMALYLIRKVKDLKDGYEYALQLMDSG
IPHVRSLIEKNGDLSNFNKLVEKID

Sequences:

>Translated_345_residues
MNTAELLRKIIRRENLTEDEARSIANSVMKAEVPEIVTAGFLVGLATKGESVEEITGFAKAMRDNALHINFPSALDTAGT
GGDGLNTLNVSTAVALLISQVYPVAKHGNRAVSGKSGSADVLEALGYNIIVKPELAEKLIKESKFVFLFAQLYHPAMKNV
ANVRKTLGVRTIFNVLGPLTNPANARYQMIGVFSKEFLPKLAEAVVRLDYDRVILYNGFPSLDEISTQGITYVYEIEKDK
IVSYTVSINDFGLKDEIPVSKLTVNDATHSALRILKAFKGKDEEARRFIGINTAMALYLIRKVKDLKDGYEYALQLMDSG
IPHVRSLIEKNGDLSNFNKLVEKID
>Mature_345_residues
MNTAELLRKIIRRENLTEDEARSIANSVMKAEVPEIVTAGFLVGLATKGESVEEITGFAKAMRDNALHINFPSALDTAGT
GGDGLNTLNVSTAVALLISQVYPVAKHGNRAVSGKSGSADVLEALGYNIIVKPELAEKLIKESKFVFLFAQLYHPAMKNV
ANVRKTLGVRTIFNVLGPLTNPANARYQMIGVFSKEFLPKLAEAVVRLDYDRVILYNGFPSLDEISTQGITYVYEIEKDK
IVSYTVSINDFGLKDEIPVSKLTVNDATHSALRILKAFKGKDEEARRFIGINTAMALYLIRKVKDLKDGYEYALQLMDSG
IPHVRSLIEKNGDLSNFNKLVEKID

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=321, Percent_Identity=33.9563862928349, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320561, Length=266, Percent_Identity=34.5864661654135, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SULTO (Q971Z7)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377163.1
- ProteinModelPortal:   Q971Z7
- SMR:   Q971Z7
- GeneID:   1459229
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1231
- NMPDR:   fig|273063.1.peg.1331
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   STOK273063:ST1231-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 38028; Mature: 38028

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAELLRKIIRRENLTEDEARSIANSVMKAEVPEIVTAGFLVGLATKGESVEEITGFAK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AMRDNALHINFPSALDTAGTGGDGLNTLNVSTAVALLISQVYPVAKHGNRAVSGKSGSAD
HHHCCCEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHH
VLEALGYNIIVKPELAEKLIKESKFVFLFAQLYHPAMKNVANVRKTLGVRTIFNVLGPLT
HHHHCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPANARYQMIGVFSKEFLPKLAEAVVRLDYDRVILYNGFPSLDEISTQGITYVYEIEKDK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCEEEEEECCCC
IVSYTVSINDFGLKDEIPVSKLTVNDATHSALRILKAFKGKDEEARRFIGINTAMALYLI
EEEEEEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHH
RKVKDLKDGYEYALQLMDSGIPHVRSLIEKNGDLSNFNKLVEKID
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNTAELLRKIIRRENLTEDEARSIANSVMKAEVPEIVTAGFLVGLATKGESVEEITGFAK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AMRDNALHINFPSALDTAGTGGDGLNTLNVSTAVALLISQVYPVAKHGNRAVSGKSGSAD
HHHCCCEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHH
VLEALGYNIIVKPELAEKLIKESKFVFLFAQLYHPAMKNVANVRKTLGVRTIFNVLGPLT
HHHHCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPANARYQMIGVFSKEFLPKLAEAVVRLDYDRVILYNGFPSLDEISTQGITYVYEIEKDK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCEEEEEECCCC
IVSYTVSINDFGLKDEIPVSKLTVNDATHSALRILKAFKGKDEEARRFIGINTAMALYLI
EEEEEEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHH
RKVKDLKDGYEYALQLMDSGIPHVRSLIEKNGDLSNFNKLVEKID
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479