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The map label for this gene is sucD2 [H]

Identifier: 15921203

GI number: 15921203

Start: 937341

End: 938120

Strand: Reverse

Name: sucD2 [H]

Synonym: ST0962

Alternate gene names: 15921203

Gene position: 938120-937341 (Counterclockwise)

Preceding gene: 15921204

Following gene: 15921200

Centisome position: 34.81

GC content: 36.92

Gene sequence:

>780_bases
ATGCTCACTTACGGAACTAAAATTGTTGCTGGAGTAAGTCCAGGCAAAGGTGGAACTACTGTTCATGGGGTACCAGTTTA
CGATACTATTGAAGATGCCCTCAAAGAACACGAAATAGATGCAAGTATAGTATTTGTACCAGCAAAATATGCACCAGATG
CTATCTACGAAGCAATTGACGGTGGAATAAAATTAGTTGTAGTAATAACAGAACACATACCAGTCCTTGATATGTTGAAA
ATCGTTAAATATGCTAAAACAAAAGGGACTAGAATTATTGGTCCAAATTGCCCCGGTCTAATAGTTCCAGAAGAGAGCTT
AATAGGAATTCTTCCACCTAGACCTTTTAAGAAAGGGAAAGTTGGTATCGTATCTAGGTCTGGAACATTAACATATGAAG
TAGCTGAAATGGTGAAAAAAGATTATGGGCAATCTACTGTTATTGGAATTGGCGGAGATCCTATAATAGGAACTGATATG
ATTGAGATTGTAAAAATGTTCGAAGAAGACCCAGAAACAGAAAGTATAGTAATGATAGGAGAAATTGGCGGTACAATGGA
AGAGAGAGTTGCAAAGATGAAAGCTGAAGGAAAGATAAAGAAAAAAATAGTTGCATATATTGCAGGCATGACAGCACCAA
GAGAAAAAAGAATGGGTCATGCTGGTGCGGTAGTTTATATGGGTATGGGAACATTTGAAAGTAAAATAAAAGCTTTAACA
GAGGCTGGAATACCAGTTGCAAAAACACCTTACGAAATACCTAAGTTACTTTCTTCTTGA

Upstream 100 bases:

>100_bases
CATTAAGTTGCATAGGTGATGCATTACGCTCATAAATAGGAACACAAGAGTACTAGTTCAGGGAATTACCGGTAAAGAAG
GCTCGTTCCACACCAAACAA

Downstream 100 bases:

>100_bases
TCTAATAAATACTACGATAGCTATAACTATTACTACACTAAATCCTACTATTAACACATACTCTGATGGGAAAGAATCAG
ATGAAGATATGACTGATTCT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 2; SCS-alpha 2 [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLTYGTKIVAGVSPGKGGTTVHGVPVYDTIEDALKEHEIDASIVFVPAKYAPDAIYEAIDGGIKLVVVITEHIPVLDMLK
IVKYAKTKGTRIIGPNCPGLIVPEESLIGILPPRPFKKGKVGIVSRSGTLTYEVAEMVKKDYGQSTVIGIGGDPIIGTDM
IEIVKMFEEDPETESIVMIGEIGGTMEERVAKMKAEGKIKKKIVAYIAGMTAPREKRMGHAGAVVYMGMGTFESKIKALT
EAGIPVAKTPYEIPKLLSS

Sequences:

>Translated_259_residues
MLTYGTKIVAGVSPGKGGTTVHGVPVYDTIEDALKEHEIDASIVFVPAKYAPDAIYEAIDGGIKLVVVITEHIPVLDMLK
IVKYAKTKGTRIIGPNCPGLIVPEESLIGILPPRPFKKGKVGIVSRSGTLTYEVAEMVKKDYGQSTVIGIGGDPIIGTDM
IEIVKMFEEDPETESIVMIGEIGGTMEERVAKMKAEGKIKKKIVAYIAGMTAPREKRMGHAGAVVYMGMGTFESKIKALT
EAGIPVAKTPYEIPKLLSS
>Mature_259_residues
MLTYGTKIVAGVSPGKGGTTVHGVPVYDTIEDALKEHEIDASIVFVPAKYAPDAIYEAIDGGIKLVVVITEHIPVLDMLK
IVKYAKTKGTRIIGPNCPGLIVPEESLIGILPPRPFKKGKVGIVSRSGTLTYEVAEMVKKDYGQSTVIGIGGDPIIGTDM
IEIVKMFEEDPETESIVMIGEIGGTMEERVAKMKAEGKIKKKIVAYIAGMTAPREKRMGHAGAVVYMGMGTFESKIKALT
EAGIPVAKTPYEIPKLLSS

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=257, Percent_Identity=49.0272373540856, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI38569423, Length=250, Percent_Identity=32.4, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI38569421, Length=250, Percent_Identity=32.4, Blast_Score=114, Evalue=9e-26,
Organism=Escherichia coli, GI1786949, Length=259, Percent_Identity=52.8957528957529, Blast_Score=260, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17550194, Length=258, Percent_Identity=47.6744186046512, Blast_Score=216, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17553126, Length=258, Percent_Identity=46.1240310077519, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17557344, Length=235, Percent_Identity=31.063829787234, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=235, Percent_Identity=29.7872340425532, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324716, Length=256, Percent_Identity=46.875, Blast_Score=206, Evalue=4e-54,
Organism=Drosophila melanogaster, GI21356559, Length=261, Percent_Identity=44.8275862068966, Blast_Score=213, Evalue=7e-56,
Organism=Drosophila melanogaster, GI28574296, Length=258, Percent_Identity=46.8992248062016, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281363477, Length=234, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281363475, Length=234, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281363473, Length=234, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 27716; Mature: 27716

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYGTKIVAGVSPGKGGTTVHGVPVYDTIEDALKEHEIDASIVFVPAKYAPDAIYEAID
CCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHC
GGIKLVVVITEHIPVLDMLKIVKYAKTKGTRIIGPNCPGLIVPEESLIGILPPRPFKKGK
CCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCEEEECHHHEEECCCCCCCCCCC
VGIVSRSGTLTYEVAEMVKKDYGQSTVIGIGGDPIIGTDMIEIVKMFEEDPETESIVMIG
EEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE
EIGGTMEERVAKMKAEGKIKKKIVAYIAGMTAPREKRMGHAGAVVYMGMGTFESKIKALT
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHH
EAGIPVAKTPYEIPKLLSS
HCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MLTYGTKIVAGVSPGKGGTTVHGVPVYDTIEDALKEHEIDASIVFVPAKYAPDAIYEAID
CCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHC
GGIKLVVVITEHIPVLDMLKIVKYAKTKGTRIIGPNCPGLIVPEESLIGILPPRPFKKGK
CCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCEEEECHHHEEECCCCCCCCCCC
VGIVSRSGTLTYEVAEMVKKDYGQSTVIGIGGDPIIGTDMIEIVKMFEEDPETESIVMIG
EEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE
EIGGTMEERVAKMKAEGKIKKKIVAYIAGMTAPREKRMGHAGAVVYMGMGTFESKIKALT
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHH
EAGIPVAKTPYEIPKLLSS
HCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]