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The map label for this gene is 15921156

Identifier: 15921156

GI number: 15921156

Start: 896024

End: 897112

Strand: Reverse

Name: 15921156

Synonym: ST0922

Alternate gene names: NA

Gene position: 897112-896024 (Counterclockwise)

Preceding gene: 15921157

Following gene: 15921155

Centisome position: 33.29

GC content: 36.0

Gene sequence:

>1089_bases
ATGGTAACGCTAGAAGAACTAAAAGCAGTCTTTAAGCCAAAATTAAAACCAATAATTTGGAGAGAAGATAGTTTAGATTT
ACTAGACCAATCAGCCTTGCCGTTTCAGACAACATACATTACAGTAAAAACACCAGAAGAAGTTGCAAAAGCAATAAAGC
TAATGCAAGTGAGAGGAGCACCGGCAATAGGAATAACAGCAGGTTATGGTATGGTTTTAGCATTGATATCAACAAAACCA
AATACATTAAATGAAGCAATAGAAGAACTAGTTAAAGCAAAACAAATAATGGATCAAGCAAGACCAACAGCAGTAAACCT
TTCTTGGGCCACCTCAAGAATGCTTAACTTTGCAAAAAAGAAAATCGAAGAAGGGGAAGCAAAAAGTGTAAGCGAACTTA
TCCAATTAATGAAAGAAGAAGCAAACAGAATTTATGAGGAAGAACTTGAAGCAGAACTAAAAATAGGTATGTACGGATTA
GAAAAAATTAGTGATGGGGATACGATACTAACCCAATGTAACGCTGGCGGATTAGCAACTGGAACAGGCTTAGGAACTGC
ACTAGCACCAGTAAAATTAGCCCACTACCTAGGAATGAAAGTCTCAGTAATAGCACCAGAAACCAGACCTTGGCTGCAAG
GAAGTAGGCTAACAGTTTATGAGCTAATGGCAGAAGGAATACAAGTAACATTAATCACAGACACTGCAGTAGGATTAGTA
ATATATAAAAACATGGTAAATAGTGTGATGGTTGGTGCAGATAGGATATTAAAAGATGGGCATGTATTCAATAAAATTGG
GACATTTAAAGAGGCTGTAATTTCCCACGAGTTAGGAATACCATTTTATGCTTTAGCACCATCATCATCCTTCGATTTAA
AAAGCAAAGTAGATGAAATAAAGATAGAAGAGAGAGATCCAAATGAGGTTAGAACAATTAGAGGAATTCCTATAGTCCCA
GAAAACGTAAAAGTATACAACCCAGTATTTGACGTCACACCACCAAAGTATATAACAGCACTAATAACTGAAAAAGGAGT
AATTTACCCACCATTCGAAAAGAACATACCAAAAATAATAGGTCTATAA

Upstream 100 bases:

>100_bases
CATAATCATCCCCATTTCAGAAAAATAAAGAAACCACCATATAAAGAACTTAAAGAAATATGCAAACATATTTAATTTCC
CTTGAAGAAAAATAAAAACG

Downstream 100 bases:

>100_bases
AAACTTATTTTGCTCCCATCTCTATTCTTTTTATGGTAAAATTAATAGCAACACTTGGTACTTCACCTGGAGGAATTTTC
GAAACATACACAAATCTCAT

Product: translation initiation factor IF-2B subunit alpha

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; MTNA-like protein; aMTNA; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MVTLEELKAVFKPKLKPIIWREDSLDLLDQSALPFQTTYITVKTPEEVAKAIKLMQVRGAPAIGITAGYGMVLALISTKP
NTLNEAIEELVKAKQIMDQARPTAVNLSWATSRMLNFAKKKIEEGEAKSVSELIQLMKEEANRIYEEELEAELKIGMYGL
EKISDGDTILTQCNAGGLATGTGLGTALAPVKLAHYLGMKVSVIAPETRPWLQGSRLTVYELMAEGIQVTLITDTAVGLV
IYKNMVNSVMVGADRILKDGHVFNKIGTFKEAVISHELGIPFYALAPSSSFDLKSKVDEIKIEERDPNEVRTIRGIPIVP
ENVKVYNPVFDVTPPKYITALITEKGVIYPPFEKNIPKIIGL

Sequences:

>Translated_362_residues
MVTLEELKAVFKPKLKPIIWREDSLDLLDQSALPFQTTYITVKTPEEVAKAIKLMQVRGAPAIGITAGYGMVLALISTKP
NTLNEAIEELVKAKQIMDQARPTAVNLSWATSRMLNFAKKKIEEGEAKSVSELIQLMKEEANRIYEEELEAELKIGMYGL
EKISDGDTILTQCNAGGLATGTGLGTALAPVKLAHYLGMKVSVIAPETRPWLQGSRLTVYELMAEGIQVTLITDTAVGLV
IYKNMVNSVMVGADRILKDGHVFNKIGTFKEAVISHELGIPFYALAPSSSFDLKSKVDEIKIEERDPNEVRTIRGIPIVP
ENVKVYNPVFDVTPPKYITALITEKGVIYPPFEKNIPKIIGL
>Mature_362_residues
MVTLEELKAVFKPKLKPIIWREDSLDLLDQSALPFQTTYITVKTPEEVAKAIKLMQVRGAPAIGITAGYGMVLALISTKP
NTLNEAIEELVKAKQIMDQARPTAVNLSWATSRMLNFAKKKIEEGEAKSVSELIQLMKEEANRIYEEELEAELKIGMYGL
EKISDGDTILTQCNAGGLATGTGLGTALAPVKLAHYLGMKVSVIAPETRPWLQGSRLTVYELMAEGIQVTLITDTAVGLV
IYKNMVNSVMVGADRILKDGHVFNKIGTFKEAVISHELGIPFYALAPSSSFDLKSKVDEIKIEERDPNEVRTIRGIPIVP
ENVKVYNPVFDVTPPKYITALITEKGVIYPPFEKNIPKIIGL

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=348, Percent_Identity=38.7931034482759, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI23943880, Length=340, Percent_Identity=33.8235294117647, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI78000158, Length=301, Percent_Identity=24.9169435215947, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI78000156, Length=301, Percent_Identity=24.9169435215947, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187607323, Length=301, Percent_Identity=24.9169435215947, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4503503, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17557462, Length=343, Percent_Identity=33.5276967930029, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17557123, Length=158, Percent_Identity=31.0126582278481, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325375, Length=391, Percent_Identity=33.5038363171356, Blast_Score=171, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6322878, Length=284, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357667, Length=351, Percent_Identity=35.042735042735, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24651647, Length=351, Percent_Identity=35.042735042735, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21358605, Length=134, Percent_Identity=37.3134328358209, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281364091, Length=263, Percent_Identity=25.4752851711027, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24659399, Length=263, Percent_Identity=25.4752851711027, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24659407, Length=263, Percent_Identity=25.4752851711027, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922816, Length=263, Percent_Identity=25.4752851711027, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39868; Mature: 39868

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLEELKAVFKPKLKPIIWREDSLDLLDQSALPFQTTYITVKTPEEVAKAIKLMQVRGA
CCCHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCC
PAIGITAGYGMVLALISTKPNTLNEAIEELVKAKQIMDQARPTAVNLSWATSRMLNFAKK
CEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
KIEEGEAKSVSELIQLMKEEANRIYEEELEAELKIGMYGLEKISDGDTILTQCNAGGLAT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
GTGLGTALAPVKLAHYLGMKVSVIAPETRPWLQGSRLTVYELMAEGIQVTLITDTAVGLV
CCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEEECCHHHHH
IYKNMVNSVMVGADRILKDGHVFNKIGTFKEAVISHELGIPFYALAPSSSFDLKSKVDEI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHE
KIEERDPNEVRTIRGIPIVPENVKVYNPVFDVTPPKYITALITEKGVIYPPFEKNIPKII
EECCCCCCHHHEECCCCCCCCCCEEECCEECCCCHHHHHHHHHCCCCEECCHHCCCCHHH
GL
CC
>Mature Secondary Structure
MVTLEELKAVFKPKLKPIIWREDSLDLLDQSALPFQTTYITVKTPEEVAKAIKLMQVRGA
CCCHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCC
PAIGITAGYGMVLALISTKPNTLNEAIEELVKAKQIMDQARPTAVNLSWATSRMLNFAKK
CEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
KIEEGEAKSVSELIQLMKEEANRIYEEELEAELKIGMYGLEKISDGDTILTQCNAGGLAT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
GTGLGTALAPVKLAHYLGMKVSVIAPETRPWLQGSRLTVYELMAEGIQVTLITDTAVGLV
CCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEEECCHHHHH
IYKNMVNSVMVGADRILKDGHVFNKIGTFKEAVISHELGIPFYALAPSSSFDLKSKVDEI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHE
KIEERDPNEVRTIRGIPIVPENVKVYNPVFDVTPPKYITALITEKGVIYPPFEKNIPKII
EECCCCCCHHHEECCCCCCCCCCEEECCEECCCCHHHHHHHHHCCCCEECCHHCCCCHHH
GL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA