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The map label for this gene is hhoB [H]

Identifier: 15921154

GI number: 15921154

Start: 894513

End: 895445

Strand: Direct

Name: hhoB [H]

Synonym: ST0920

Alternate gene names: 15921154

Gene position: 894513-895445 (Clockwise)

Preceding gene: 15921153

Following gene: 15921158

Centisome position: 33.19

GC content: 35.05

Gene sequence:

>933_bases
ATGTATATTTTTAAGTTTATGGATGAGTTTTTAATTATGGATTATTCTTCAATCGTTGAAGAGGTGTCTAAGTCAGTTGT
AACTATTTTAACTAAACAATTAACGCTTGATGAGTTTTTAATGCCATCTATAGCTGAAGGATTAGGTTCTGGGTTTAGTG
TTGGCAATGGTTTTGTAATTACTTCTTATCACGTTATTCAGAATTCAAGAAATATTGCAGTTGTTAGCAAGGACGGTTTT
AGTAGTGAGGCTGATGTGATAGCTGTAAATCCTTTTAATGATCTCGCTCTTCTTTATACTAATCTTAATTTAAAGGCTTT
GAAGTTTTCTGAGAAGGTTAAGGTTGGTGAAGGAGTTTTAGCTATTGGTAGTCCATTAGGTTTAGATAGTGTAACCTTGG
GAATAATAAGTAGCGTAGATAGGACTATACAATCTCCTCTAGGTAATCCGCTCTATGTCTTGCAAACCGATGCTGCTGTT
AATCCAGGGAATAGTGGTGGTCCTCTAATAAATACTAAGGGAGAGGTTGTTGGTGTTGTTACTGCTATGATTCCTTATGC
TCAAGGAATAGGGTTTGCTATTCCTTCAAAGCTTGTTCTTAGTTTTCTGAAGAATGTGGAAAGAAATAATGGTAAATATG
TTAGACCTTATTTGGGGATCCGAGTCATTAAATTGAACAAGGCTATAAGTACTTATTTTAATTTGTCTTCGGATTCCGGT
GTTTTAGTTGTTGCTGTTGATGAGGATAGTCCAGCCTACGAGGCTGGAATTAGAAGAGGTGATATAATCACTGAGGTTAA
TGGTAAGAAGATTGAGTCTCAACTAGATTTGGTTGCTAGTATAGATGAGACAGGATTAGAGGAAATTGAAATGAAGATTT
TAAGAGGTAAAGATAAGATTTCTATAAAAGTAGCTCCAGTACCTTTAGGTTAA

Upstream 100 bases:

>100_bases
AATAGGTATGAGATTTATAACCCAACTATTGATGTTATTTCCGTTATTAAGAAGATTGAGGAAAATTTTTCAGCGAGAAA
AGTCGTTATAAAGGGATCTA

Downstream 100 bases:

>100_bases
CAAAATTGTTTTAGCTCCATGTATTATTAGTTTTTTCAAATCTTCTCCTATCTTTTCACAAGATCCCGTGTATATTGCTT
CATCAATTTCTTTTTCTCTA

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MYIFKFMDEFLIMDYSSIVEEVSKSVVTILTKQLTLDEFLMPSIAEGLGSGFSVGNGFVITSYHVIQNSRNIAVVSKDGF
SSEADVIAVNPFNDLALLYTNLNLKALKFSEKVKVGEGVLAIGSPLGLDSVTLGIISSVDRTIQSPLGNPLYVLQTDAAV
NPGNSGGPLINTKGEVVGVVTAMIPYAQGIGFAIPSKLVLSFLKNVERNNGKYVRPYLGIRVIKLNKAISTYFNLSSDSG
VLVVAVDEDSPAYEAGIRRGDIITEVNGKKIESQLDLVASIDETGLEEIEMKILRGKDKISIKVAPVPLG

Sequences:

>Translated_310_residues
MYIFKFMDEFLIMDYSSIVEEVSKSVVTILTKQLTLDEFLMPSIAEGLGSGFSVGNGFVITSYHVIQNSRNIAVVSKDGF
SSEADVIAVNPFNDLALLYTNLNLKALKFSEKVKVGEGVLAIGSPLGLDSVTLGIISSVDRTIQSPLGNPLYVLQTDAAV
NPGNSGGPLINTKGEVVGVVTAMIPYAQGIGFAIPSKLVLSFLKNVERNNGKYVRPYLGIRVIKLNKAISTYFNLSSDSG
VLVVAVDEDSPAYEAGIRRGDIITEVNGKKIESQLDLVASIDETGLEEIEMKILRGKDKISIKVAPVPLG
>Mature_310_residues
MYIFKFMDEFLIMDYSSIVEEVSKSVVTILTKQLTLDEFLMPSIAEGLGSGFSVGNGFVITSYHVIQNSRNIAVVSKDGF
SSEADVIAVNPFNDLALLYTNLNLKALKFSEKVKVGEGVLAIGSPLGLDSVTLGIISSVDRTIQSPLGNPLYVLQTDAAV
NPGNSGGPLINTKGEVVGVVTAMIPYAQGIGFAIPSKLVLSFLKNVERNNGKYVRPYLGIRVIKLNKAISTYFNLSSDSG
VLVVAVDEDSPAYEAGIRRGDIITEVNGKKIESQLDLVASIDETGLEEIEMKILRGKDKISIKVAPVPLG

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=311, Percent_Identity=35.048231511254, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7019477, Length=311, Percent_Identity=34.0836012861736, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI4506141, Length=311, Percent_Identity=33.1189710610932, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI22129776, Length=335, Percent_Identity=30.4477611940298, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1789629, Length=270, Percent_Identity=34.4444444444444, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1786356, Length=247, Percent_Identity=39.2712550607287, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789630, Length=281, Percent_Identity=32.3843416370107, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646839, Length=319, Percent_Identity=35.1097178683386, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 33280; Mature: 33280

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIFKFMDEFLIMDYSSIVEEVSKSVVTILTKQLTLDEFLMPSIAEGLGSGFSVGNGFVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TSYHVIQNSRNIAVVSKDGFSSEADVIAVNPFNDLALLYTNLNLKALKFSEKVKVGEGVL
EEEEEEECCCCEEEEECCCCCCCCCEEEECCCCCEEEEEECCCEEEEEECCCEECCCCEE
AIGSPLGLDSVTLGIISSVDRTIQSPLGNPLYVLQTDAAVNPGNSGGPLINTKGEVVGVV
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEECCCCHHHHH
TAMIPYAQGIGFAIPSKLVLSFLKNVERNNGKYVRPYLGIRVIKLNKAISTYFNLSSDSG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHCEEEEEECCHHHHHEECCCCCC
VLVVAVDEDSPAYEAGIRRGDIITEVNGKKIESQLDLVASIDETGLEEIEMKILRGKDKI
EEEEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
SIKVAPVPLG
EEEEEECCCC
>Mature Secondary Structure
MYIFKFMDEFLIMDYSSIVEEVSKSVVTILTKQLTLDEFLMPSIAEGLGSGFSVGNGFVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TSYHVIQNSRNIAVVSKDGFSSEADVIAVNPFNDLALLYTNLNLKALKFSEKVKVGEGVL
EEEEEEECCCCEEEEECCCCCCCCCEEEECCCCCEEEEEECCCEEEEEECCCEECCCCEE
AIGSPLGLDSVTLGIISSVDRTIQSPLGNPLYVLQTDAAVNPGNSGGPLINTKGEVVGVV
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEECCCCHHHHH
TAMIPYAQGIGFAIPSKLVLSFLKNVERNNGKYVRPYLGIRVIKLNKAISTYFNLSSDSG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHCEEEEEECCHHHHHEECCCCCC
VLVVAVDEDSPAYEAGIRRGDIITEVNGKKIESQLDLVASIDETGLEEIEMKILRGKDKI
EEEEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
SIKVAPVPLG
EEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]