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The map label for this gene is acdA [H]

Identifier: 15921151

GI number: 15921151

Start: 892645

End: 893721

Strand: Reverse

Name: acdA [H]

Synonym: ST0916

Alternate gene names: 15921151

Gene position: 893721-892645 (Counterclockwise)

Preceding gene: 15921155

Following gene: 15921150

Centisome position: 33.17

GC content: 35.38

Gene sequence:

>1077_bases
ATGTCCGAAGAAGCAGAGCTTATTATCCAATCAGCAAATGAACTCTCAAAACAGCTAGACTCTACAAGTGAAGAACAAGG
AATATTCCCAAGAAAAAACCTTGAATTATTAGCGCAACAAGGATTCATGGGAATATTAATACCGAAACCTTACGGTTTAG
AATTACCAGCAAAAACATTCGTAGATGTAGTAAAAACCATAGCAAAAGCCTCACCATCAACAGCGTGGCTTTATGTAACA
CACATAGCTTCAACAATAGCATTACATGCATTTGCAAACCAGCAAGTTAAAGAAAAATACATGAAAGACTTAGTTGAAGG
AAAAATACTAATCGGAGCTGCTGGAACGGAAAGTGTAGGAGGAGCAATAAACGCAGTATTAAATACTACAGCAGAATTAA
AGGGAGATAAATACGTAATAAACGGTTCAAAAACATTCATAACTGGTGCTGGAGAACTGGACTTATACTTACTGATCTCA
AAAATACAAGGGCAACAAAAACCCGGGGTATTCTTACTTGAGAAAAACCAAGTAAAGAGCGGACAAAAATTCACGTCATT
AGGAATGAAAGGAATATCTTGGGGAGAATTAATAATTGAAAATGCAGAAGTACCAAAGGACTATATGATAATTGATGATG
CAGTAAAATTCTTAGGAGTATTAGGAAGAATAGGAATGTTAGGAGTATCAGCAATAGCTTATGGTTTAGCAGAAGGAGCG
TTTGAAGAAGCCTTAAATCATGTGAAAAACAGAAAACTCGGACAAAATACTTTAGCTTCATTTGAAGGAGTCCAAATATA
CTTAGCAGAAATGGCAGCAAAAGTTGAAGCACTAAAACAAATGGTTTATCAGGCTGCAGAACAGTCCACATCACTCCCAG
CAATATTAAAAGCAAGAATATTTAACACAGAAACAGCACTAGAAGTTATCGATAAAGCACTGAGAATAACGGGAGGACAC
GGATTTAGTAATGCATTAAAAATAGAAAAATATTATAGAGATGTTAGGGCAACAATGTTACACTTCCAAACATTAGAATT
ATCAAAGAAAGTATTAGGAGGATTGCTGATAGCATAA

Upstream 100 bases:

>100_bases
CACATTATATTTATATACATTTTCACTTTAAAATAATTCCTTCATTAAAGCCAGTTTTATATTAGAAAATTTTAAAATCA
CAAAATACTCAACTGAAGAT

Downstream 100 bases:

>100_bases
TGCCAATACGAGACGAAAAAACATATGCAAGAATGAGTTTAAACGACTTCTTAATTTCTTATGAAAGACTCAAAAAAGGA
GATTTAAGGCTATCGGCATT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSEEAELIIQSANELSKQLDSTSEEQGIFPRKNLELLAQQGFMGILIPKPYGLELPAKTFVDVVKTIAKASPSTAWLYVT
HIASTIALHAFANQQVKEKYMKDLVEGKILIGAAGTESVGGAINAVLNTTAELKGDKYVINGSKTFITGAGELDLYLLIS
KIQGQQKPGVFLLEKNQVKSGQKFTSLGMKGISWGELIIENAEVPKDYMIIDDAVKFLGVLGRIGMLGVSAIAYGLAEGA
FEEALNHVKNRKLGQNTLASFEGVQIYLAEMAAKVEALKQMVYQAAEQSTSLPAILKARIFNTETALEVIDKALRITGGH
GFSNALKIEKYYRDVRATMLHFQTLELSKKVLGGLLIA

Sequences:

>Translated_358_residues
MSEEAELIIQSANELSKQLDSTSEEQGIFPRKNLELLAQQGFMGILIPKPYGLELPAKTFVDVVKTIAKASPSTAWLYVT
HIASTIALHAFANQQVKEKYMKDLVEGKILIGAAGTESVGGAINAVLNTTAELKGDKYVINGSKTFITGAGELDLYLLIS
KIQGQQKPGVFLLEKNQVKSGQKFTSLGMKGISWGELIIENAEVPKDYMIIDDAVKFLGVLGRIGMLGVSAIAYGLAEGA
FEEALNHVKNRKLGQNTLASFEGVQIYLAEMAAKVEALKQMVYQAAEQSTSLPAILKARIFNTETALEVIDKALRITGGH
GFSNALKIEKYYRDVRATMLHFQTLELSKKVLGGLLIA
>Mature_357_residues
SEEAELIIQSANELSKQLDSTSEEQGIFPRKNLELLAQQGFMGILIPKPYGLELPAKTFVDVVKTIAKASPSTAWLYVTH
IASTIALHAFANQQVKEKYMKDLVEGKILIGAAGTESVGGAINAVLNTTAELKGDKYVINGSKTFITGAGELDLYLLISK
IQGQQKPGVFLLEKNQVKSGQKFTSLGMKGISWGELIIENAEVPKDYMIIDDAVKFLGVLGRIGMLGVSAIAYGLAEGAF
EEALNHVKNRKLGQNTLASFEGVQIYLAEMAAKVEALKQMVYQAAEQSTSLPAILKARIFNTETALEVIDKALRITGGHG
FSNALKIEKYYRDVRATMLHFQTLELSKKVLGGLLIA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=356, Percent_Identity=26.9662921348315, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=23.4042553191489, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI187960098, Length=277, Percent_Identity=29.6028880866426, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4557231, Length=277, Percent_Identity=29.6028880866426, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4501859, Length=355, Percent_Identity=27.0422535211268, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21361497, Length=357, Percent_Identity=24.6498599439776, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226958412, Length=355, Percent_Identity=23.0985915492958, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI226958414, Length=369, Percent_Identity=23.5772357723577, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4501857, Length=351, Percent_Identity=24.5014245014245, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557235, Length=266, Percent_Identity=25.9398496240602, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI76496475, Length=266, Percent_Identity=25.9398496240602, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=370, Percent_Identity=27.2972972972973, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786223, Length=375, Percent_Identity=26.1333333333333, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=314, Percent_Identity=28.6624203821656, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17533517, Length=361, Percent_Identity=27.4238227146814, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17534899, Length=352, Percent_Identity=25, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=352, Percent_Identity=24.7159090909091, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=340, Percent_Identity=24.1176470588235, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=358, Percent_Identity=25.6983240223464, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=375, Percent_Identity=25.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=27.4368231046931, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=336, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=25.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551932, Length=272, Percent_Identity=25, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=231, Percent_Identity=25.5411255411255, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=24.468085106383, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646207, Length=342, Percent_Identity=24.5614035087719, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24660351, Length=274, Percent_Identity=25.9124087591241, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666513, Length=311, Percent_Identity=26.6881028938907, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355753, Length=356, Percent_Identity=24.438202247191, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363737, Length=268, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 38883; Mature: 38752

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEAELIIQSANELSKQLDSTSEEQGIFPRKNLELLAQQGFMGILIPKPYGLELPAKTF
CCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCHHHH
VDVVKTIAKASPSTAWLYVTHIASTIALHAFANQQVKEKYMKDLVEGKILIGAAGTESVG
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHH
GAINAVLNTTAELKGDKYVINGSKTFITGAGELDLYLLISKIQGQQKPGVFLLEKNQVKS
HHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCC
GQKFTSLGMKGISWGELIIENAEVPKDYMIIDDAVKFLGVLGRIGMLGVSAIAYGLAEGA
CCHHHHHCCCCCCHHHHEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEALNHVKNRKLGQNTLASFEGVQIYLAEMAAKVEALKQMVYQAAEQSTSLPAILKARI
HHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FNTETALEVIDKALRITGGHGFSNALKIEKYYRDVRATMLHFQTLELSKKVLGGLLIA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEEAELIIQSANELSKQLDSTSEEQGIFPRKNLELLAQQGFMGILIPKPYGLELPAKTF
CCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCHHHH
VDVVKTIAKASPSTAWLYVTHIASTIALHAFANQQVKEKYMKDLVEGKILIGAAGTESVG
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHH
GAINAVLNTTAELKGDKYVINGSKTFITGAGELDLYLLISKIQGQQKPGVFLLEKNQVKS
HHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCC
GQKFTSLGMKGISWGELIIENAEVPKDYMIIDDAVKFLGVLGRIGMLGVSAIAYGLAEGA
CCHHHHHCCCCCCHHHHEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEALNHVKNRKLGQNTLASFEGVQIYLAEMAAKVEALKQMVYQAAEQSTSLPAILKARI
HHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FNTETALEVIDKALRITGGHGFSNALKIEKYYRDVRATMLHFQTLELSKKVLGGLLIA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]