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The map label for this gene is thpS [H]

Identifier: 15921130

GI number: 15921130

Start: 871632

End: 873428

Strand: Reverse

Name: thpS [H]

Synonym: ST0894

Alternate gene names: 15921130

Gene position: 873428-871632 (Counterclockwise)

Preceding gene: 15921132

Following gene: 15921128

Centisome position: 32.41

GC content: 31.0

Gene sequence:

>1797_bases
GTGAGATATTTAGTATTTCTGATATTAATCCTTCCTCTTTTTATTCCAATCTCATTAGCTTCAATTCCCCATCCTTCTTC
TCAATATATTTATTTTAACGTTAGTTTATCAGAAGGGTATAAAATAGTCGTAGTCTCCTACTCTAATCAAACTTTTCCAC
TTTTGATCTTTACTCCAACACAGTTTATGTACTGGATCAAAAACTTAACTACAAGTGCAATAGTAGTAACGAATATAAGT
AAGGGAAATTATTCTTTCTATTTGCCTCAAGGAAATTACATTGTAGTCATAGATGGTTATAAGAACTCTTATCCTTCCCC
TCAGAACTATAAGTTGTATACTATACCCTACAATGTTTATGCGTTGATAACACAGCCAAAAAACGATTCAGCTATAGGTA
TAGCTGCTTATGGTGTAAGTAACAAATCTTCATGTGTTATAACTACAAATGCGATATTAGGCTATTTTAATATATCATCA
ATCTATGCGTATAACTCCACGTTCTATATGCATTATGGTGCGTCTCTGCAATTAAATGCTGTATTACGTGGAGGTAATCA
GAGTTTATTTTTGCAAAATGTAATTAGCTTTATTACGAATAAAAACATTCTACAGTTTGTTACAAACATATGGAACTTAA
CTTCTCCCTTAGCAAGTTTAAATAGTTCTTTCTTTTACTTTAACTCTACTTCTTATTCTACGTATAGACTTCCCTTTGCT
GGCTATCTTATAATAAATGTAAGCAATGTAAGTAACGGGGTAAAAATTTCCTTTGGATATATTATTATTCAAAATGGGTC
AATAATAGAGCCTATGGTAAGGTTCTTTACTACTGCTTACTTTCCATTTAAAGGTTACATACTTGTAGACCCTTTCAATT
TAACCGGGAATTATCATGCTTATGATACTGAATTCGTTTTTGGAGGGTATGAAGACGGTGAAATTACTACCTTTATTTCA
TTAAATGCCACCTTGGCACTTTATTATAATTCAACTTATGGCTGGACTCCTTTTAGGTCAATTTACACATATGGTGTAAA
TACTGGTGAGGGTGTAACAAATCTTCATGTTTCATTAATTCATGGCTACGCTAATGTTTACGTAGGTAATGAGACCTTAT
CCCTTCTTACAACTCATTTTAATCCCTCAAATCCATATTTGCTTTACATCCGTGTTCTCCCTTACAATTACTCCTTTTAC
GTTAATTCTAGTTATAAAATATATTTCCCAGAAAACATAAGTTCTAAATACGAAGTAGCTAGACTAAATTCCATCTATGT
TAACGGCGTAAAAGTTGAAAATGGTTATATAATTAGCTATAGTACTCTGCCTAAAGTAGTTGAGATTTATGTAAATTACA
CCTATTATTTTTACGTATCTATTATTCTACCTAATGGTAGTATATTAAGAGGCTGGTATAGTAATGGTAGTAAAATAACG
TTGCCAAAAGAAATTTACTTTAACAATAATGAAAGATATATTCTCACAACCAATACAGTGTATGTTCAGCAACCTTTAAT
TAACTATACTCCGAAATATATAAAGCAATTTAAGGTAATGGTAGATAACTCGACTTATTGGGTAAATCAAGGGAGTAATA
TAACCTTGTATTCCCCTACATTTCTTATTTTAACAGTAAAATGGATAGGTACTTATAATGTAACTAACGGAGCAACAGTT
GAAGTTACTTCTCCTATAGTGGAGAAAGAAATAATAGGTATAAATTATGTAAATCTTTGCATTATATTAGTTTTAGTCAT
AGCTTTAGTATGGCTTATAAAGCGTATTCTTTCATAA

Upstream 100 bases:

>100_bases
ATAATAATTAAAATAGAAAAAATTAGCTAAACTATCATATCATTCTTACACTCCTTGATTTTGTAAAAAATATTAATACC
GGAATTAAATACAACATTAT

Downstream 100 bases:

>100_bases
GTCTATCCATAGAACAAAAATCGGAAAAAGTATGATAAGCATTATAGCCAACTTCATAATACTTGTTTAAAGCCTCCTTC
ACCTTTCTTGCGAATTCCTC

Product: thermopsin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRYLVFLILILPLFIPISLASIPHPSSQYIYFNVSLSEGYKIVVVSYSNQTFPLLIFTPTQFMYWIKNLTTSAIVVTNIS
KGNYSFYLPQGNYIVVIDGYKNSYPSPQNYKLYTIPYNVYALITQPKNDSAIGIAAYGVSNKSSCVITTNAILGYFNISS
IYAYNSTFYMHYGASLQLNAVLRGGNQSLFLQNVISFITNKNILQFVTNIWNLTSPLASLNSSFFYFNSTSYSTYRLPFA
GYLIINVSNVSNGVKISFGYIIIQNGSIIEPMVRFFTTAYFPFKGYILVDPFNLTGNYHAYDTEFVFGGYEDGEITTFIS
LNATLALYYNSTYGWTPFRSIYTYGVNTGEGVTNLHVSLIHGYANVYVGNETLSLLTTHFNPSNPYLLYIRVLPYNYSFY
VNSSYKIYFPENISSKYEVARLNSIYVNGVKVENGYIISYSTLPKVVEIYVNYTYYFYVSIILPNGSILRGWYSNGSKIT
LPKEIYFNNNERYILTTNTVYVQQPLINYTPKYIKQFKVMVDNSTYWVNQGSNITLYSPTFLILTVKWIGTYNVTNGATV
EVTSPIVEKEIIGINYVNLCIILVLVIALVWLIKRILS

Sequences:

>Translated_598_residues
MRYLVFLILILPLFIPISLASIPHPSSQYIYFNVSLSEGYKIVVVSYSNQTFPLLIFTPTQFMYWIKNLTTSAIVVTNIS
KGNYSFYLPQGNYIVVIDGYKNSYPSPQNYKLYTIPYNVYALITQPKNDSAIGIAAYGVSNKSSCVITTNAILGYFNISS
IYAYNSTFYMHYGASLQLNAVLRGGNQSLFLQNVISFITNKNILQFVTNIWNLTSPLASLNSSFFYFNSTSYSTYRLPFA
GYLIINVSNVSNGVKISFGYIIIQNGSIIEPMVRFFTTAYFPFKGYILVDPFNLTGNYHAYDTEFVFGGYEDGEITTFIS
LNATLALYYNSTYGWTPFRSIYTYGVNTGEGVTNLHVSLIHGYANVYVGNETLSLLTTHFNPSNPYLLYIRVLPYNYSFY
VNSSYKIYFPENISSKYEVARLNSIYVNGVKVENGYIISYSTLPKVVEIYVNYTYYFYVSIILPNGSILRGWYSNGSKIT
LPKEIYFNNNERYILTTNTVYVQQPLINYTPKYIKQFKVMVDNSTYWVNQGSNITLYSPTFLILTVKWIGTYNVTNGATV
EVTSPIVEKEIIGINYVNLCIILVLVIALVWLIKRILS
>Mature_598_residues
MRYLVFLILILPLFIPISLASIPHPSSQYIYFNVSLSEGYKIVVVSYSNQTFPLLIFTPTQFMYWIKNLTTSAIVVTNIS
KGNYSFYLPQGNYIVVIDGYKNSYPSPQNYKLYTIPYNVYALITQPKNDSAIGIAAYGVSNKSSCVITTNAILGYFNISS
IYAYNSTFYMHYGASLQLNAVLRGGNQSLFLQNVISFITNKNILQFVTNIWNLTSPLASLNSSFFYFNSTSYSTYRLPFA
GYLIINVSNVSNGVKISFGYIIIQNGSIIEPMVRFFTTAYFPFKGYILVDPFNLTGNYHAYDTEFVFGGYEDGEITTFIS
LNATLALYYNSTYGWTPFRSIYTYGVNTGEGVTNLHVSLIHGYANVYVGNETLSLLTTHFNPSNPYLLYIRVLPYNYSFY
VNSSYKIYFPENISSKYEVARLNSIYVNGVKVENGYIISYSTLPKVVEIYVNYTYYFYVSIILPNGSILRGWYSNGSKIT
LPKEIYFNNNERYILTTNTVYVQQPLINYTPKYIKQFKVMVDNSTYWVNQGSNITLYSPTFLILTVKWIGTYNVTNGATV
EVTSPIVEKEIIGINYVNLCIILVLVIALVWLIKRILS

Specific function: May represent a new class of acid proteases. It digests proteins and peptides in acidic solution [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=May be linked to cells by covalent linkages through some side chains [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A5 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007981 [H]

Pfam domain/function: PF05317 Thermopsin [H]

EC number: =3.4.23.42 [H]

Molecular weight: Translated: 68103; Mature: 68103

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLVFLILILPLFIPISLASIPHPSSQYIYFNVSLSEGYKIVVVSYSNQTFPLLIFTPT
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEECCCEEEEEEECCH
QFMYWIKNLTTSAIVVTNISKGNYSFYLPQGNYIVVIDGYKNSYPSPQNYKLYTIPYNVY
HHHHHHHHCCCCEEEEEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCEEEEEECEEEE
ALITQPKNDSAIGIAAYGVSNKSSCVITTNAILGYFNISSIYAYNSTFYMHYGASLQLNA
EEEECCCCCCEEEEEEECCCCCCCEEEEEEEEEEEEEEEEEEEECCEEEEEECCCEEEEE
VLRGGNQSLFLQNVISFITNKNILQFVTNIWNLTSPLASLNSSFFYFNSTSYSTYRLPFA
EEECCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCEEEECCEE
GYLIINVSNVSNGVKISFGYIIIQNGSIIEPMVRFFTTAYFPFKGYILVDPFNLTGNYHA
EEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHEEECCEECEEEEECEECCCCEEE
YDTEFVFGGYEDGEITTFISLNATLALYYNSTYGWTPFRSIYTYGVNTGEGVTNLHVSLI
EECEEEECCCCCCCEEEEEEECEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEEEE
HGYANVYVGNETLSLLTTHFNPSNPYLLYIRVLPYNYSFYVNSSYKIYFPENISSKYEVA
EEEEEEEECCCEEEEEEEECCCCCCEEEEEEEECCEEEEEECCEEEEEECCCCCCCEEEE
RLNSIYVNGVKVENGYIISYSTLPKVVEIYVNYTYYFYVSIILPNGSILRGWYSNGSKIT
EEEEEEEEEEEEECCEEEEECCCCEEEEEEEEEEEEEEEEEEECCCCEEEEEECCCCEEE
LPKEIYFNNNERYILTTNTVYVQQPLINYTPKYIKQFKVMVDNSTYWVNQGSNITLYSPT
ECCEEEECCCCEEEEEECEEEEECCHHCCCHHHHEEEEEEEECCEEEEECCCEEEEECCE
FLILTVKWIGTYNVTNGATVEVTSPIVEKEIIGINYVNLCIILVLVIALVWLIKRILS
EEEEEEEEEEEEECCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLVFLILILPLFIPISLASIPHPSSQYIYFNVSLSEGYKIVVVSYSNQTFPLLIFTPT
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEECCCEEEEEEECCH
QFMYWIKNLTTSAIVVTNISKGNYSFYLPQGNYIVVIDGYKNSYPSPQNYKLYTIPYNVY
HHHHHHHHCCCCEEEEEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCEEEEEECEEEE
ALITQPKNDSAIGIAAYGVSNKSSCVITTNAILGYFNISSIYAYNSTFYMHYGASLQLNA
EEEECCCCCCEEEEEEECCCCCCCEEEEEEEEEEEEEEEEEEEECCEEEEEECCCEEEEE
VLRGGNQSLFLQNVISFITNKNILQFVTNIWNLTSPLASLNSSFFYFNSTSYSTYRLPFA
EEECCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCEEEECCEE
GYLIINVSNVSNGVKISFGYIIIQNGSIIEPMVRFFTTAYFPFKGYILVDPFNLTGNYHA
EEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHEEECCEECEEEEECEECCCCEEE
YDTEFVFGGYEDGEITTFISLNATLALYYNSTYGWTPFRSIYTYGVNTGEGVTNLHVSLI
EECEEEECCCCCCCEEEEEEECEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEEEE
HGYANVYVGNETLSLLTTHFNPSNPYLLYIRVLPYNYSFYVNSSYKIYFPENISSKYEVA
EEEEEEEECCCEEEEEEEECCCCCCEEEEEEEECCEEEEEECCEEEEEECCCCCCCEEEE
RLNSIYVNGVKVENGYIISYSTLPKVVEIYVNYTYYFYVSIILPNGSILRGWYSNGSKIT
EEEEEEEEEEEEECCEEEEECCCCEEEEEEEEEEEEEEEEEEECCCCEEEEEECCCCEEE
LPKEIYFNNNERYILTTNTVYVQQPLINYTPKYIKQFKVMVDNSTYWVNQGSNITLYSPT
ECCEEEECCCCEEEEEECEEEEECCHHCCCHHHHEEEEEEEECCEEEEECCCEEEEECCE
FLILTVKWIGTYNVTNGATVEVTSPIVEKEIIGINYVNLCIILVLVIALVWLIKRILS
EEEEEEEEEEEEECCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2104843 [H]