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The map label for this gene is htpX1

Identifier: 15921070

GI number: 15921070

Start: 813943

End: 814878

Strand: Direct

Name: htpX1

Synonym: ST0836

Alternate gene names: 15921070

Gene position: 813943-814878 (Clockwise)

Preceding gene: 15921069

Following gene: 15921073

Centisome position: 30.2

GC content: 31.73

Gene sequence:

>936_bases
GTGGAAATAGGTACTTCATTAAAAATTAATATGATTATAGCTTTATTTTTAACGATAGTTTCAGAGGGAATATTTTCTTT
AGTGATTATAAATTTTTTAAAATTTCCCGTTATTTTTTCTATAATATTTTTACTTATATTATGGCTAATCCAGTGGCTAA
TATCCCCATATTTAGTGGAGAGAAATTCAGTTGAGGTTACCAGAGATGACCCTAGTTACGGATGGGTTTATGAATTAGTT
GAAAATGTAGCAAGAAGGGCTGGTATTAAAACTCCTAGAGTTTTTTTAGTTGATGAGCCTTATCCTAATGCATTTGCTTA
TGGAAATTACGTTACAGGAAAGAGAATTGGGATAACTATTCCACTCCTTCAAATTCTTACTACAGAAGAACTTGAGAGTG
TGATAGGACATGAGCTTGGGCATATTAAACATAATGATGTTGAAATAGGATTAGCTATAGGTTTAATACCATCAATTTTA
GGTTTCATTAGTAATATATTACTTACTGTAGGTTGGGCTACCCTTATATTTGCTGTTGACGAGTTTGACATATTAGTTGG
ACTAACTATGTTAGCAATTGGTGGTGTGTTATTCGTGATAACGTTCTTCCTTCAACTATTTGTCTTATGGTTCAATAGGC
TAAGAGAGAGTTTTGCCGATTACTTTTCTTATGAACTATTTAGAGAGAGAGCATGGAATTTAGCTAAAGCTTTGGCTAAA
ATAGAAATTTACATGCAAAACATTAGATTAGATCCGTTTAGAGGAATTATAGTTACTATCCCGCCGACAAAAGTAAAGGA
AAGTGACCCAGATCTTCTTATTGAAGATCTATTGAGAGAAAAAACAAATATCTTTTCTGATATCCTATCTACACATCCAC
ACCCAGCAAAAAGAATTAAGATGATTTATAAATTAACAAAACCAATGATTTTTTAG

Upstream 100 bases:

>100_bases
TTAAGCAGACAAGTAGAAGAATTTAAGGAAAAAATAAGACAAGTAGAAGAGGCTTTGAAAGCATTAACTTAATATTATTT
TTTATTCTTAATCTAAGGGT

Downstream 100 bases:

>100_bases
CCCTTAACTAAACCAATTATTAACCCAATAATGAACAGTATCGAATTATAAGGTAGGATTGAAATTTCATTTTTGACGAA
TGATTCAGCTGTGCTTGCAT

Product: heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MEIGTSLKINMIIALFLTIVSEGIFSLVIINFLKFPVIFSIIFLLILWLIQWLISPYLVERNSVEVTRDDPSYGWVYELV
ENVARRAGIKTPRVFLVDEPYPNAFAYGNYVTGKRIGITIPLLQILTTEELESVIGHELGHIKHNDVEIGLAIGLIPSIL
GFISNILLTVGWATLIFAVDEFDILVGLTMLAIGGVLFVITFFLQLFVLWFNRLRESFADYFSYELFRERAWNLAKALAK
IEIYMQNIRLDPFRGIIVTIPPTKVKESDPDLLIEDLLREKTNIFSDILSTHPHPAKRIKMIYKLTKPMIF

Sequences:

>Translated_311_residues
MEIGTSLKINMIIALFLTIVSEGIFSLVIINFLKFPVIFSIIFLLILWLIQWLISPYLVERNSVEVTRDDPSYGWVYELV
ENVARRAGIKTPRVFLVDEPYPNAFAYGNYVTGKRIGITIPLLQILTTEELESVIGHELGHIKHNDVEIGLAIGLIPSIL
GFISNILLTVGWATLIFAVDEFDILVGLTMLAIGGVLFVITFFLQLFVLWFNRLRESFADYFSYELFRERAWNLAKALAK
IEIYMQNIRLDPFRGIIVTIPPTKVKESDPDLLIEDLLREKTNIFSDILSTHPHPAKRIKMIYKLTKPMIF
>Mature_311_residues
MEIGTSLKINMIIALFLTIVSEGIFSLVIINFLKFPVIFSIIFLLILWLIQWLISPYLVERNSVEVTRDDPSYGWVYELV
ENVARRAGIKTPRVFLVDEPYPNAFAYGNYVTGKRIGITIPLLQILTTEELESVIGHELGHIKHNDVEIGLAIGLIPSIL
GFISNILLTVGWATLIFAVDEFDILVGLTMLAIGGVLFVITFFLQLFVLWFNRLRESFADYFSYELFRERAWNLAKALAK
IEIYMQNIRLDPFRGIIVTIPPTKVKESDPDLLIEDLLREKTNIFSDILSTHPHPAKRIKMIYKLTKPMIF

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family

Homologues:

Organism=Escherichia coli, GI1788133, Length=308, Percent_Identity=25.3246753246753, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HTPX1_SULTO (Q973R2)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376739.1
- ProteinModelPortal:   Q973R2
- GeneID:   1458798
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0836
- NMPDR:   fig|273063.1.peg.907
- HOGENOM:   HBG739460
- OMA:   LERKENK
- ProtClustDB:   CLSK803163
- BioCyc:   STOK273063:ST0836-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00188
- InterPro:   IPR022919
- InterPro:   IPR001915

Pfam domain/function: PF01435 Peptidase_M48

EC number: 3.4.24.- [C]

Molecular weight: Translated: 35622; Mature: 35622

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 138-138

Signals:

None

Transmembrane regions:

HASH(0xc01d210)-; HASH(0xd2c9210)-; HASH(0xdb0def4)-; HASH(0xdb16964)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGTSLKINMIIALFLTIVSEGIFSLVIINFLKFPVIFSIIFLLILWLIQWLISPYLVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RNSVEVTRDDPSYGWVYELVENVARRAGIKTPRVFLVDEPYPNAFAYGNYVTGKRIGITI
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCCCCHHH
PLLQILTTEELESVIGHELGHIKHNDVEIGLAIGLIPSILGFISNILLTVGWATLIFAVD
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFDILVGLTMLAIGGVLFVITFFLQLFVLWFNRLRESFADYFSYELFRERAWNLAKALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEIYMQNIRLDPFRGIIVTIPPTKVKESDPDLLIEDLLREKTNIFSDILSTHPHPAKRIK
HHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MIYKLTKPMIF
HHHHHHCCCCH
>Mature Secondary Structure
MEIGTSLKINMIIALFLTIVSEGIFSLVIINFLKFPVIFSIIFLLILWLIQWLISPYLVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RNSVEVTRDDPSYGWVYELVENVARRAGIKTPRVFLVDEPYPNAFAYGNYVTGKRIGITI
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCCCCHHH
PLLQILTTEELESVIGHELGHIKHNDVEIGLAIGLIPSILGFISNILLTVGWATLIFAVD
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFDILVGLTMLAIGGVLFVITFFLQLFVLWFNRLRESFADYFSYELFRERAWNLAKALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEIYMQNIRLDPFRGIIVTIPPTKVKESDPDLLIEDLLREKTNIFSDILSTHPHPAKRIK
HHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MIYKLTKPMIF
HHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11572479