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The map label for this gene is ybeK [C]

Identifier: 15921038

GI number: 15921038

Start: 780742

End: 781668

Strand: Reverse

Name: ybeK [C]

Synonym: ST0803

Alternate gene names: 15921038

Gene position: 781668-780742 (Counterclockwise)

Preceding gene: 15921039

Following gene: 15921034

Centisome position: 29.01

GC content: 35.6

Gene sequence:

>927_bases
ATGAGGCATTTCATAATAGATTGTGATACAGCTGAAGATGACATAATGAGCCTTTTTATGTTACTCAGAAATAATATAGA
TGTCCAAGGAATAACTATTGTTGAAGGAAACATATCTTATGAGCAAGAAATAAATAACGCATTATGGAGCTTAGAGTTTG
TAGGAAAAGATATCCCAGTTTATCCTGGTAGTGATAGACCGCTAGTTAAACAATTCAGAAGTGTCCCAGAGGTTCACGGC
AAGGGAGGAATTGGAGATGAGGTAGTAAAACCCAGTAAACTTAAACCACAAAATAAGAAAGCTGTAGATGCCATTGTTGA
GATTGCTGACAGATATGCTGGTGAATTAGAGTTCTTGGCAATATCCCCGTTAACAAATCTTGCCTTAGCTTACTTAAAAG
ACAAGTCAGTAGTTGAAAAGATAAAAAAGGTTTGGATAATGGGAGGAACAGTGTGGGGGAGAGGAAACATAACCCCAGTT
GCCGAATATAATATTTGGGTAGACCCAGATTCAGCAAAAATTGTTTTTAACTCTGGTTTCGATATTACCATGGTACCGTG
GGATGTTATTGTTAACTATCCAATCACCGATGAAGAATGGGAACAAATAAAGACGATGAAGACTAAGATGGCTCAATTTT
ACGTTAAGATTTACACTCATTATAGAAAATATTCTATGGAAAAAGAGAAAATAAAGGGGACTCCTCACCCCGACTTAATT
ACAACTTCTGTGGCTCTCAATAGAAATGTAGTATTAAAATCGGAAAGGCAATATGTGGATATTGAAAATTGTGATTGCTT
AACCAGAGGAATGACTGTTATTGACTATTTAGGAATTTGGGGTAAAGAACCCAATGCTGAAATAATTTATGAGATAAACA
AGAAAGAGTTCTATTCAATGTTAATCGACTTACTCAATTGGTTCTAG

Upstream 100 bases:

>100_bases
AGGAATTAAGCAAAGCTGGAGTAAAGTTTTATACGAGAGATAATCCCAAAGAAGTATACTTAAAGCTTAAGAGACTACTT
GATTTTAAAAATATATTTGT

Downstream 100 bases:

>100_bases
TATCTAATTAGGATCAGCAGTCAAACCTAGTACATACGGAGATTTCCATCTCTTTTATCAAATCCCTCAAAAACATATAA
TACTTATAAAGCTCTTGAAT

Product: inosine-uridine preferring nucleoside hydrolase

Products: D-ribose; purine

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRHFIIDCDTAEDDIMSLFMLLRNNIDVQGITIVEGNISYEQEINNALWSLEFVGKDIPVYPGSDRPLVKQFRSVPEVHG
KGGIGDEVVKPSKLKPQNKKAVDAIVEIADRYAGELEFLAISPLTNLALAYLKDKSVVEKIKKVWIMGGTVWGRGNITPV
AEYNIWVDPDSAKIVFNSGFDITMVPWDVIVNYPITDEEWEQIKTMKTKMAQFYVKIYTHYRKYSMEKEKIKGTPHPDLI
TTSVALNRNVVLKSERQYVDIENCDCLTRGMTVIDYLGIWGKEPNAEIIYEINKKEFYSMLIDLLNWF

Sequences:

>Translated_308_residues
MRHFIIDCDTAEDDIMSLFMLLRNNIDVQGITIVEGNISYEQEINNALWSLEFVGKDIPVYPGSDRPLVKQFRSVPEVHG
KGGIGDEVVKPSKLKPQNKKAVDAIVEIADRYAGELEFLAISPLTNLALAYLKDKSVVEKIKKVWIMGGTVWGRGNITPV
AEYNIWVDPDSAKIVFNSGFDITMVPWDVIVNYPITDEEWEQIKTMKTKMAQFYVKIYTHYRKYSMEKEKIKGTPHPDLI
TTSVALNRNVVLKSERQYVDIENCDCLTRGMTVIDYLGIWGKEPNAEIIYEINKKEFYSMLIDLLNWF
>Mature_308_residues
MRHFIIDCDTAEDDIMSLFMLLRNNIDVQGITIVEGNISYEQEINNALWSLEFVGKDIPVYPGSDRPLVKQFRSVPEVHG
KGGIGDEVVKPSKLKPQNKKAVDAIVEIADRYAGELEFLAISPLTNLALAYLKDKSVVEKIKKVWIMGGTVWGRGNITPV
AEYNIWVDPDSAKIVFNSGFDITMVPWDVIVNYPITDEEWEQIKTMKTKMAQFYVKIYTHYRKYSMEKEKIKGTPHPDLI
TTSVALNRNVVLKSERQYVDIENCDCLTRGMTVIDYLGIWGKEPNAEIIYEINKKEFYSMLIDLLNWF

Specific function: Unknown

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=307, Percent_Identity=30.9446254071661, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788486, Length=308, Percent_Identity=27.2727272727273, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786213, Length=280, Percent_Identity=32.1428571428571, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32565474, Length=290, Percent_Identity=32.0689655172414, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17565698, Length=301, Percent_Identity=26.578073089701, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320608, Length=178, Percent_Identity=32.0224719101124, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641839, Length=330, Percent_Identity=27.5757575757576, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583915, Length=329, Percent_Identity=26.4437689969605, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641837, Length=203, Percent_Identity=30.5418719211823, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.1

Molecular weight: Translated: 35343; Mature: 35343

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHFIIDCDTAEDDIMSLFMLLRNNIDVQGITIVEGNISYEQEINNALWSLEFVGKDIPV
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHEEEEECCCCCCC
YPGSDRPLVKQFRSVPEVHGKGGIGDEVVKPSKLKPQNKKAVDAIVEIADRYAGELEFLA
CCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
ISPLTNLALAYLKDKSVVEKIKKVWIMGGTVWGRGNITPVAEYNIWVDPDSAKIVFNSGF
ECCHHHHHHHHHCCHHHHHHHHHHEEECCEEECCCCCCEEEEEEEEECCCCCEEEEECCC
DITMVPWDVIVNYPITDEEWEQIKTMKTKMAQFYVKIYTHYRKYSMEKEKIKGTPHPDLI
CEEEECHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEE
TTSVALNRNVVLKSERQYVDIENCDCLTRGMTVIDYLGIWGKEPNAEIIYEINKKEFYSM
EEEEEECCCEEEECCCCEECCCCCCHHHHCCHHHHHHHCCCCCCCCEEEEEECHHHHHHH
LIDLLNWF
HHHHHHCC
>Mature Secondary Structure
MRHFIIDCDTAEDDIMSLFMLLRNNIDVQGITIVEGNISYEQEINNALWSLEFVGKDIPV
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHEEEEECCCCCCC
YPGSDRPLVKQFRSVPEVHGKGGIGDEVVKPSKLKPQNKKAVDAIVEIADRYAGELEFLA
CCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
ISPLTNLALAYLKDKSVVEKIKKVWIMGGTVWGRGNITPVAEYNIWVDPDSAKIVFNSGF
ECCHHHHHHHHHCCHHHHHHHHHHEEECCEEECCCCCCEEEEEEEEECCCCCEEEEECCC
DITMVPWDVIVNYPITDEEWEQIKTMKTKMAQFYVKIYTHYRKYSMEKEKIKGTPHPDLI
CEEEECHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEE
TTSVALNRNVVLKSERQYVDIENCDCLTRGMTVIDYLGIWGKEPNAEIIYEINKKEFYSM
EEEEEECCCEEEECCCCEECCCCCCHHHHCCHHHHHHHCCCCCCCCEEEEEECHHHHHHH
LIDLLNWF
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-D-ribosylpurine; H2O

Specific reaction: an N-D-ribosylpurine + H2O = D-ribose + a purine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA