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The map label for this gene is napA [H]

Identifier: 15920958

GI number: 15920958

Start: 712082

End: 713242

Strand: Reverse

Name: napA [H]

Synonym: ST0728

Alternate gene names: 15920958

Gene position: 713242-712082 (Counterclockwise)

Preceding gene: 15920959

Following gene: 15920955

Centisome position: 26.47

GC content: 32.3

Gene sequence:

>1161_bases
ATGGAAGAAATTTATATAGCTCTTTTTGATATAGCTCTTTTTATTTTTATTGCTGAATTTTTTAAGACACAGCTAAGAAA
AATTGATTTGCCAGACCTGGTAAGCGAACTTATTGCTGGTATGATCATAGGACCTTATGCAGTTGGTGGGCTGATAAATG
ATATTTTGGGTTTTCATCTAATAACTCTAGATCAATACGTCCTTTTTATATCTGAATTTGCTGTAATTCTTATTATCTTT
GCTTCTGGTTTAGAACATGGTCTAAGTCCGCTTAAAGAAGCCGGAATATTAGGATTTATGGGAGCCACTTTCGGTGCATT
ATTACCATTTTTTGCCGGATATTTTATATATGCTAACTCTTTCGGAAGCAATTCGGCATTATTTTTGGGAGTAAGCTTAG
GTGCTACAAGTTTAGCTGCTGTAGCATATCTAATAGAGGGGATTAATACTAAGGGTGTTAAGTTTTTAATTTCTGCGTCA
GCCGTAGATGATATAGTAGATTTAATCTTATTATCTACAGTACTTATTCTTATTAAAAACTCCACTATAGTTATAACGTC
TATATCTTTAAGAATAGTGTCACTAATTGTAATTTGGTTAGTAATTTTATTTCTTTCCATAACGATTATCCCAAGGATAG
CTAACAAGTTGAGTGATGTTTATATAGAAGAATTCACAATGCTCGTATTATTTGGATTAACATTATTTATGGTTTATTTA
GGATATTCCCCAATTATATCTGCCTTTGTAGCTGGTGTATCAATCTCTAATTCCTTGAAGAGTGAAAAAATTAAGGAAAT
TGTTACTATAGTACTCTCAGTATTTGGTCCGATGTTCTTTGTAACTGTTGGAGCGGAAGTAAATTTGCTTTTAATTAATT
TAAACACTTTATTACTTGCGCTGGAGCTCACGAGTATAGCAACTATTTTTAAAATGCTCGGAATTATGCCATTTGCTTAT
CTATATATTAAAGATCTTAAAAGGGCAATGATTATTGCCCTAGGAATGGTCCCTAGAGGAGAAACTGGCTTAGTAGTAGC
ATCAATAGGTTTAAGTCTAAACGCTTTAGATCAAAATGAGTTTGAGAGTATAGTTTTCATGTCAATTCTGACTACAGTAA
TAGGTGCTCTAGTTATTAAACGTTATTCTCATCAATTATAG

Upstream 100 bases:

>100_bases
AATGAGGCTTCAGTAGAAGAAGTTAAGAAGGCTTATGAGGAGTTTAAGGCTGAGATAGGTAAAAGTTAATTTTATTTTTA
TAAAAAAAATTATTACCGTC

Downstream 100 bases:

>100_bases
TAGGATTTTCAAGTTTACCTATCTTTTCAACTTCAGCAACCATAATTGCATTGTTAATTGGTTTTAGTGAGAACTCTGAT
ACTTCTTCAGCACCTATATA

Product: Na(+)/H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MEEIYIALFDIALFIFIAEFFKTQLRKIDLPDLVSELIAGMIIGPYAVGGLINDILGFHLITLDQYVLFISEFAVILIIF
ASGLEHGLSPLKEAGILGFMGATFGALLPFFAGYFIYANSFGSNSALFLGVSLGATSLAAVAYLIEGINTKGVKFLISAS
AVDDIVDLILLSTVLILIKNSTIVITSISLRIVSLIVIWLVILFLSITIIPRIANKLSDVYIEEFTMLVLFGLTLFMVYL
GYSPIISAFVAGVSISNSLKSEKIKEIVTIVLSVFGPMFFVTVGAEVNLLLINLNTLLLALELTSIATIFKMLGIMPFAY
LYIKDLKRAMIIALGMVPRGETGLVVASIGLSLNALDQNEFESIVFMSILTTVIGALVIKRYSHQL

Sequences:

>Translated_386_residues
MEEIYIALFDIALFIFIAEFFKTQLRKIDLPDLVSELIAGMIIGPYAVGGLINDILGFHLITLDQYVLFISEFAVILIIF
ASGLEHGLSPLKEAGILGFMGATFGALLPFFAGYFIYANSFGSNSALFLGVSLGATSLAAVAYLIEGINTKGVKFLISAS
AVDDIVDLILLSTVLILIKNSTIVITSISLRIVSLIVIWLVILFLSITIIPRIANKLSDVYIEEFTMLVLFGLTLFMVYL
GYSPIISAFVAGVSISNSLKSEKIKEIVTIVLSVFGPMFFVTVGAEVNLLLINLNTLLLALELTSIATIFKMLGIMPFAY
LYIKDLKRAMIIALGMVPRGETGLVVASIGLSLNALDQNEFESIVFMSILTTVIGALVIKRYSHQL
>Mature_386_residues
MEEIYIALFDIALFIFIAEFFKTQLRKIDLPDLVSELIAGMIIGPYAVGGLINDILGFHLITLDQYVLFISEFAVILIIF
ASGLEHGLSPLKEAGILGFMGATFGALLPFFAGYFIYANSFGSNSALFLGVSLGATSLAAVAYLIEGINTKGVKFLISAS
AVDDIVDLILLSTVLILIKNSTIVITSISLRIVSLIVIWLVILFLSITIIPRIANKLSDVYIEEFTMLVLFGLTLFMVYL
GYSPIISAFVAGVSISNSLKSEKIKEIVTIVLSVFGPMFFVTVGAEVNLLLINLNTLLLALELTSIATIFKMLGIMPFAY
LYIKDLKRAMIIALGMVPRGETGLVVASIGLSLNALDQNEFESIVFMSILTTVIGALVIKRYSHQL

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 41968; Mature: 41968

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIYIALFDIALFIFIAEFFKTQLRKIDLPDLVSELIAGMIIGPYAVGGLINDILGFHL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLDQYVLFISEFAVILIIFASGLEHGLSPLKEAGILGFMGATFGALLPFFAGYFIYANS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEC
FGSNSALFLGVSLGATSLAAVAYLIEGINTKGVKFLISASAVDDIVDLILLSTVLILIKN
CCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC
STIVITSISLRIVSLIVIWLVILFLSITIIPRIANKLSDVYIEEFTMLVLFGLTLFMVYL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYSPIISAFVAGVSISNSLKSEKIKEIVTIVLSVFGPMFFVTVGAEVNLLLINLNTLLLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEHHHHHHH
LELTSIATIFKMLGIMPFAYLYIKDLKRAMIIALGMVPRGETGLVVASIGLSLNALDQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEECCCHHH
FESIVFMSILTTVIGALVIKRYSHQL
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEEIYIALFDIALFIFIAEFFKTQLRKIDLPDLVSELIAGMIIGPYAVGGLINDILGFHL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLDQYVLFISEFAVILIIFASGLEHGLSPLKEAGILGFMGATFGALLPFFAGYFIYANS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEC
FGSNSALFLGVSLGATSLAAVAYLIEGINTKGVKFLISASAVDDIVDLILLSTVLILIKN
CCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC
STIVITSISLRIVSLIVIWLVILFLSITIIPRIANKLSDVYIEEFTMLVLFGLTLFMVYL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYSPIISAFVAGVSISNSLKSEKIKEIVTIVLSVFGPMFFVTVGAEVNLLLINLNTLLLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEHHHHHHH
LELTSIATIFKMLGIMPFAYLYIKDLKRAMIIALGMVPRGETGLVVASIGLSLNALDQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEECCCHHH
FESIVFMSILTTVIGALVIKRYSHQL
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]