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The map label for this gene is lhr [C]

Identifier: 15920808

GI number: 15920808

Start: 576108

End: 578222

Strand: Direct

Name: lhr [C]

Synonym: ST0590

Alternate gene names: 15920808

Gene position: 576108-578222 (Clockwise)

Preceding gene: 15920805

Following gene: 15920815

Centisome position: 21.38

GC content: 33.81

Gene sequence:

>2115_bases
ATGGAAACAATTTCTATTGACGATTTGCCGTTAGACATAAAAATTATAGATATTTTAAAAAGAAGAGGAATTAGAACTCT
TAACCCACCACAATCTGAAGCAATAAGAAAAGGTTTACTAGATGGAAAAAGACTCTTAGTAACATCTCCTACTGCTTCTG
GTAAAACTCTCATTGCAGAACTAGGTATGATAAATTATCTTCTATCAAAAGGCGGAAAAGCAATATATATTACCCCACTT
AGAGCATTAACTAATGAAAAATATAATACGTTTAAAGATTGGGAAACTCTTGGTATAAAAACTGGAATGACAAGTGGAGA
TTACGATACTGATGACGCATGGCTCGAAAATTATGATATAATAGTAACTACTTACGAAAAATTAGATTCTTTATGGAGAC
ATAAGGCTAAATGGCTTAACGAGGTTTCATATTTTGTTTTAGATGAGTTTCATTATTTAAACGATCCAGAAAGGGGTCCT
ACCGTTGAATCAGTTGCTATTAGAGCGAAGAAAAGAGGCATAGTATTAGGATTAAGTGCAACAATTAGTAATGGTAAAGA
GATAGCTAACTGGTTAAATGCTGAACTAGTAGCTACTAATTGGAGACCCGTCCCGCTAAAAGAAGGAATAATATACCCAG
AAAAGAAAGGATTTGTAGTAGTGTACAAGGATAATACCAGCAGGAAAGTATATGGGGATGATGCTATAATAGCTTACACA
CTAGATATAGTTTCAAAAGGAGGACAAGTTTTAGTGTTTCGCTCTTCGAGAAAATTAGCCGAAAATACAGCTAGAAAAAT
AGTTCAATATATGAATTTTGTAAAATTAGAGGATAAGAAATTACTGGAAATCGCTAGAAAAATTAAAGAAGTCGAAGATG
CAGGGAGTAATGAGAAAGAGGACTTATATAACCTTGTATTAAGGGGTGTTGCTTATCATCATGCAGGTCTCTCTAAAGGA
CTTAGGGATATAATAGAATCTTCTTTTAGAGATAGAATATTGAAAGTGATAGTGGCAACACCCACATTAGCTGCTGGAGT
TAATTTACCTGCTAGGGCTGTAGTTATAGGTGATATTTATAGATATAATAGAAAAGTTGTCGGATATATGGATTTAATCC
CAGTTATGGATTATAAGCAAATGAGTGGCAGGGCTGGAAGACCAGGTTTTGATGAAAATGGAGAAGCTGTTGTAGTTGTT
AGGAACAAAAGAGAGGCAGAAAAAGTATACGAAAGGTATTTAATGTCTGATGTGGAACCAATTGAATCAAAATTAGGTTC
AGAAAGTGCATTTTATTCCTTCCTTATTAGTATTATAGCATCTGAAGGTGAAAAAACCACAGAGGAACTAATGGAATATG
TAAAGGAAACCTTACTTCCGAAAGAACTAGCTAAAAAATATTTTAGATCTGGGTTAGATTGGTTACTACAACATGATATC
TTTGCTGAAATCAGTGATAAAATCACATTAACTAGATTTGGAAGAAGAATCTCAGATCTATATATAAATCCTTTCACTGC
AGTAACAATTAGAGAAGCCTTAGAGAAGAATGAGAAAGGATGCGAAATAGCATATCTTCACTTGTTAGCTTATACTCCAG
ATGGTCCTTCAATTGGAGTTAGTAGAGCTGAAGAAGATGCACTTATAGATGAGTTAAATTGTGAACTATTTGTTGATGAG
CCTGAAGATGAATACGAATTTTCAAATTACATATCAGCATTAAAAGTAGCTTATATTGTTTATGATTGGGTAAATGAAAT
AGATGAAGATACAATCCTAGGGAAGTATGGAATAGGATCAGGTGATTTAAGGGCTATAATAGATACAATGGATTGGTTAA
CTTATTCTGGTTATCATGTAGCCTCCGTCCTAGAATTAAAAGATCATAAGGATATCTTAGAAGAACTTCATGCTAGAGTT
AAAGACGGAGTTAAACCAGAGCTGATTGAATTGGTAAAGATTCCTGGAATAGGAAGAGTAAGAGCCAGACTACTTTATCA
ACATGATATTAAGAAACCAGAAGACATTGTACTAAACCCAGAAAAGGTTAAGCAACTTTTAGGTCCTAACTTAGGTGAAA
AAATTGTCAGAGAAGCTGCAAGAACTATTGCTTGA

Upstream 100 bases:

>100_bases
GAACTTATATAATGCTATATAGAGTTACATTTTTCAAATAAGGACTATTAAGGGCAAAAATCCTTTTAAGACTTAATAAA
AGAAAGATTATAGTTTTACA

Downstream 100 bases:

>100_bases
ATATATATTATATCAGAAACAAGAATTCTCAATTCCATGTGATAGCATTGAAAAAATAAGGAAATTATTTTTAGCCTTAG
GTAGAAATGTAGTAGTGAAA

Product: helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
METISIDDLPLDIKIIDILKRRGIRTLNPPQSEAIRKGLLDGKRLLVTSPTASGKTLIAELGMINYLLSKGGKAIYITPL
RALTNEKYNTFKDWETLGIKTGMTSGDYDTDDAWLENYDIIVTTYEKLDSLWRHKAKWLNEVSYFVLDEFHYLNDPERGP
TVESVAIRAKKRGIVLGLSATISNGKEIANWLNAELVATNWRPVPLKEGIIYPEKKGFVVVYKDNTSRKVYGDDAIIAYT
LDIVSKGGQVLVFRSSRKLAENTARKIVQYMNFVKLEDKKLLEIARKIKEVEDAGSNEKEDLYNLVLRGVAYHHAGLSKG
LRDIIESSFRDRILKVIVATPTLAAGVNLPARAVVIGDIYRYNRKVVGYMDLIPVMDYKQMSGRAGRPGFDENGEAVVVV
RNKREAEKVYERYLMSDVEPIESKLGSESAFYSFLISIIASEGEKTTEELMEYVKETLLPKELAKKYFRSGLDWLLQHDI
FAEISDKITLTRFGRRISDLYINPFTAVTIREALEKNEKGCEIAYLHLLAYTPDGPSIGVSRAEEDALIDELNCELFVDE
PEDEYEFSNYISALKVAYIVYDWVNEIDEDTILGKYGIGSGDLRAIIDTMDWLTYSGYHVASVLELKDHKDILEELHARV
KDGVKPELIELVKIPGIGRVRARLLYQHDIKKPEDIVLNPEKVKQLLGPNLGEKIVREAARTIA

Sequences:

>Translated_704_residues
METISIDDLPLDIKIIDILKRRGIRTLNPPQSEAIRKGLLDGKRLLVTSPTASGKTLIAELGMINYLLSKGGKAIYITPL
RALTNEKYNTFKDWETLGIKTGMTSGDYDTDDAWLENYDIIVTTYEKLDSLWRHKAKWLNEVSYFVLDEFHYLNDPERGP
TVESVAIRAKKRGIVLGLSATISNGKEIANWLNAELVATNWRPVPLKEGIIYPEKKGFVVVYKDNTSRKVYGDDAIIAYT
LDIVSKGGQVLVFRSSRKLAENTARKIVQYMNFVKLEDKKLLEIARKIKEVEDAGSNEKEDLYNLVLRGVAYHHAGLSKG
LRDIIESSFRDRILKVIVATPTLAAGVNLPARAVVIGDIYRYNRKVVGYMDLIPVMDYKQMSGRAGRPGFDENGEAVVVV
RNKREAEKVYERYLMSDVEPIESKLGSESAFYSFLISIIASEGEKTTEELMEYVKETLLPKELAKKYFRSGLDWLLQHDI
FAEISDKITLTRFGRRISDLYINPFTAVTIREALEKNEKGCEIAYLHLLAYTPDGPSIGVSRAEEDALIDELNCELFVDE
PEDEYEFSNYISALKVAYIVYDWVNEIDEDTILGKYGIGSGDLRAIIDTMDWLTYSGYHVASVLELKDHKDILEELHARV
KDGVKPELIELVKIPGIGRVRARLLYQHDIKKPEDIVLNPEKVKQLLGPNLGEKIVREAARTIA
>Mature_704_residues
METISIDDLPLDIKIIDILKRRGIRTLNPPQSEAIRKGLLDGKRLLVTSPTASGKTLIAELGMINYLLSKGGKAIYITPL
RALTNEKYNTFKDWETLGIKTGMTSGDYDTDDAWLENYDIIVTTYEKLDSLWRHKAKWLNEVSYFVLDEFHYLNDPERGP
TVESVAIRAKKRGIVLGLSATISNGKEIANWLNAELVATNWRPVPLKEGIIYPEKKGFVVVYKDNTSRKVYGDDAIIAYT
LDIVSKGGQVLVFRSSRKLAENTARKIVQYMNFVKLEDKKLLEIARKIKEVEDAGSNEKEDLYNLVLRGVAYHHAGLSKG
LRDIIESSFRDRILKVIVATPTLAAGVNLPARAVVIGDIYRYNRKVVGYMDLIPVMDYKQMSGRAGRPGFDENGEAVVVV
RNKREAEKVYERYLMSDVEPIESKLGSESAFYSFLISIIASEGEKTTEELMEYVKETLLPKELAKKYFRSGLDWLLQHDI
FAEISDKITLTRFGRRISDLYINPFTAVTIREALEKNEKGCEIAYLHLLAYTPDGPSIGVSRAEEDALIDELNCELFVDE
PEDEYEFSNYISALKVAYIVYDWVNEIDEDTILGKYGIGSGDLRAIIDTMDWLTYSGYHVASVLELKDHKDILEELHARV
KDGVKPELIELVKIPGIGRVRARLLYQHDIKKPEDIVLNPEKVKQLLGPNLGEKIVREAARTIA

Specific function: Unknown

COG id: COG1204

COG function: function code R; Superfamily II helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Homo sapiens, GI139394648, Length=743, Percent_Identity=26.3795423956931, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI76880486, Length=421, Percent_Identity=31.1163895486936, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI40217847, Length=467, Percent_Identity=29.1220556745182, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI169218225, Length=467, Percent_Identity=28.6937901498929, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI110556640, Length=710, Percent_Identity=24.9295774647887, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI130484567, Length=405, Percent_Identity=30.3703703703704, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI193211480, Length=449, Percent_Identity=27.3942093541203, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI67782311, Length=428, Percent_Identity=25.7009345794392, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI222831595, Length=96, Percent_Identity=39.5833333333333, Blast_Score=73, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17537127, Length=436, Percent_Identity=32.1100917431193, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17537519, Length=491, Percent_Identity=30.7535641547862, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71995032, Length=736, Percent_Identity=25.8152173913043, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI86563272, Length=412, Percent_Identity=29.8543689320388, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17542826, Length=460, Percent_Identity=27.1739130434783, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133930973, Length=456, Percent_Identity=26.0964912280702, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71995036, Length=444, Percent_Identity=26.1261261261261, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17552356, Length=120, Percent_Identity=38.3333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321710, Length=426, Percent_Identity=30.7511737089202, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321020, Length=440, Percent_Identity=30.4545454545455, Blast_Score=161, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6322411, Length=432, Percent_Identity=28.9351851851852, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI9755332, Length=428, Percent_Identity=28.7383177570093, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323430, Length=203, Percent_Identity=32.512315270936, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647182, Length=424, Percent_Identity=34.4339622641509, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17933644, Length=529, Percent_Identity=28.5444234404537, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28574898, Length=440, Percent_Identity=29.7727272727273, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24660651, Length=488, Percent_Identity=27.8688524590164, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17864608, Length=421, Percent_Identity=27.790973871734, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17933658, Length=188, Percent_Identity=31.9148936170213, Blast_Score=83, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HELS_SULTO (Q974S1)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376477.1
- ProteinModelPortal:   Q974S1
- SMR:   Q974S1
- GeneID:   1458536
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0590
- NMPDR:   fig|273063.1.peg.645
- HOGENOM:   HBG496908
- OMA:   RIEYGAK
- ProtClustDB:   CLSK803393
- BioCyc:   STOK273063:ST0590-MONOMER
- HAMAP:   MF_00442
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR022965
- InterPro:   IPR003583
- SMART:   SM00487
- SMART:   SM00490
- SMART:   SM00278

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C

EC number: 3.6.1.-

Molecular weight: Translated: 79720; Mature: 79720

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METISIDDLPLDIKIIDILKRRGIRTLNPPQSEAIRKGLLDGKRLLVTSPTASGKTLIAE
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
LGMINYLLSKGGKAIYITPLRALTNEKYNTFKDWETLGIKTGMTSGDYDTDDAWLENYDI
HHHHHHHHHCCCCEEEEECHHHHCCCCCCCHHHHHHHCEECCCCCCCCCCCCHHHCCCCE
IVTTYEKLDSLWRHKAKWLNEVSYFVLDEFHYLNDPERGPTVESVAIRAKKRGIVLGLSA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEEC
TISNGKEIANWLNAELVATNWRPVPLKEGIIYPEKKGFVVVYKDNTSRKVYGDDAIIAYT
CCCCCHHHHHHHCCEEEECCCCCCCCCCCEECCCCCCEEEEEECCCCCEEECCCEEEEEE
LDIVSKGGQVLVFRSSRKLAENTARKIVQYMNFVKLEDKKLLEIARKIKEVEDAGSNEKE
EEHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHH
DLYNLVLRGVAYHHAGLSKGLRDIIESSFRDRILKVIVATPTLAAGVNLPARAVVIGDIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEHHHH
RYNRKVVGYMDLIPVMDYKQMSGRAGRPGFDENGEAVVVVRNKREAEKVYERYLMSDVEP
HHCCCEEEHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCH
IESKLGSESAFYSFLISIIASEGEKTTEELMEYVKETLLPKELAKKYFRSGLDWLLQHDI
HHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FAEISDKITLTRFGRRISDLYINPFTAVTIREALEKNEKGCEIAYLHLLAYTPDGPSIGV
HHHHHCCCHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCC
SRAEEDALIDELNCELFVDEPEDEYEFSNYISALKVAYIVYDWVNEIDEDTILGKYGIGS
CCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
GDLRAIIDTMDWLTYSGYHVASVLELKDHKDILEELHARVKDGVKPELIELVKIPGIGRV
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHH
RARLLYQHDIKKPEDIVLNPEKVKQLLGPNLGEKIVREAARTIA
HHHHHHHHCCCCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
METISIDDLPLDIKIIDILKRRGIRTLNPPQSEAIRKGLLDGKRLLVTSPTASGKTLIAE
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
LGMINYLLSKGGKAIYITPLRALTNEKYNTFKDWETLGIKTGMTSGDYDTDDAWLENYDI
HHHHHHHHHCCCCEEEEECHHHHCCCCCCCHHHHHHHCEECCCCCCCCCCCCHHHCCCCE
IVTTYEKLDSLWRHKAKWLNEVSYFVLDEFHYLNDPERGPTVESVAIRAKKRGIVLGLSA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEEC
TISNGKEIANWLNAELVATNWRPVPLKEGIIYPEKKGFVVVYKDNTSRKVYGDDAIIAYT
CCCCCHHHHHHHCCEEEECCCCCCCCCCCEECCCCCCEEEEEECCCCCEEECCCEEEEEE
LDIVSKGGQVLVFRSSRKLAENTARKIVQYMNFVKLEDKKLLEIARKIKEVEDAGSNEKE
EEHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHH
DLYNLVLRGVAYHHAGLSKGLRDIIESSFRDRILKVIVATPTLAAGVNLPARAVVIGDIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEHHHH
RYNRKVVGYMDLIPVMDYKQMSGRAGRPGFDENGEAVVVVRNKREAEKVYERYLMSDVEP
HHCCCEEEHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCH
IESKLGSESAFYSFLISIIASEGEKTTEELMEYVKETLLPKELAKKYFRSGLDWLLQHDI
HHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FAEISDKITLTRFGRRISDLYINPFTAVTIREALEKNEKGCEIAYLHLLAYTPDGPSIGV
HHHHHCCCHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCC
SRAEEDALIDELNCELFVDEPEDEYEFSNYISALKVAYIVYDWVNEIDEDTILGKYGIGS
CCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
GDLRAIIDTMDWLTYSGYHVASVLELKDHKDILEELHARVKDGVKPELIELVKIPGIGRV
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHH
RARLLYQHDIKKPEDIVLNPEKVKQLLGPNLGEKIVREAARTIA
HHHHHHHHCCCCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479