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The map label for this gene is cutM [H]

Identifier: 15920780

GI number: 15920780

Start: 553038

End: 553874

Strand: Reverse

Name: cutM [H]

Synonym: ST0562

Alternate gene names: 15920780

Gene position: 553874-553038 (Counterclockwise)

Preceding gene: 15920781

Following gene: 15920779

Centisome position: 20.55

GC content: 35.24

Gene sequence:

>837_bases
GTGTATCCGCCAAAGTTTGGATATGTTATTCCGGATAATCTAAACGAAGCTTTAGAGTTCTTAGAAGAACATCAAGACGC
TAGACCATTAGCTGGTGGCCATAGTTTAATACCAATGCTAAAACTAAGATTAATAAGGCCTTCATATATTGTAGAAATCA
GAAGATTCTCTAATTTAAGTTATATTACTAAAGATGGTAACTTATATAAAATCGGAGCATTAACTACGCATTATAACATC
TCGAAATCATCAATACCTCTACTGAGTGAAACAGCTAGTAACATTGGAGATCCGCAAGTAAGAAATATGGGAACAATAGG
GGGTAGTATTTCTCATTTAGATCCTTCCGCAGATTATCCAGCAGCTCTCATTGCAATGGATGCAAAAGTAAAAATTACAA
GTAGAAAAGGAGACAGAGTGGTTAACTTTAAATCATTTGCAAAGGACATGTTCACTCCAGATTTAAATCCAGGTGAACTT
GTTACTGAAATTCAGGTTCCAACATTTGAAGGTTACAAATTCTCTTATCAAAAGCTAGAAAGAAGAGCTGGAGATTTTGC
TATAGTTGGTGTAGCATTACTCCTAAAATTATCTGGTGATGTGATTGAAGATGTTAGAATTGGATTAACAGCAGTAAATA
ATGTAGCTGTTAGAGCAAAAGGTGCTGAAGAAGAGTTACTCGGTAAAAGGTTAAATGACGAGATAATTGAAAAAGCGGCA
ACAAGAGCTATGGAGAGTGCAAACCCCACTTCAGATTTAAGAGGCTCTGCTGAATATAAGAAAAAGATGGTAAAAGTTTT
AACTAAGAGAGCTATTATTACAGCGTTAAAGAGGTGA

Upstream 100 bases:

>100_bases
CCTATAAGGGAAAAACTTATTATTTTTGTAGTCCGATGTGCATGGCTGAATTCAAAAAGAGACCAGAAAAATATATTAAA
TAAGTTTGTTACCTAATTTT

Downstream 100 bases:

>100_bases
AACAGATGAAAATAATCAATAGTGATCAAAAAGTAAAAATTACATTAAAGATAAATGGCGAAAAGTATGAGACTGAAGTT
GAACCTAGAAGATTATTAGT

Product: carbon-monoxide dehydrogenase middle subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MYPPKFGYVIPDNLNEALEFLEEHQDARPLAGGHSLIPMLKLRLIRPSYIVEIRRFSNLSYITKDGNLYKIGALTTHYNI
SKSSIPLLSETASNIGDPQVRNMGTIGGSISHLDPSADYPAALIAMDAKVKITSRKGDRVVNFKSFAKDMFTPDLNPGEL
VTEIQVPTFEGYKFSYQKLERRAGDFAIVGVALLLKLSGDVIEDVRIGLTAVNNVAVRAKGAEEELLGKRLNDEIIEKAA
TRAMESANPTSDLRGSAEYKKKMVKVLTKRAIITALKR

Sequences:

>Translated_278_residues
MYPPKFGYVIPDNLNEALEFLEEHQDARPLAGGHSLIPMLKLRLIRPSYIVEIRRFSNLSYITKDGNLYKIGALTTHYNI
SKSSIPLLSETASNIGDPQVRNMGTIGGSISHLDPSADYPAALIAMDAKVKITSRKGDRVVNFKSFAKDMFTPDLNPGEL
VTEIQVPTFEGYKFSYQKLERRAGDFAIVGVALLLKLSGDVIEDVRIGLTAVNNVAVRAKGAEEELLGKRLNDEIIEKAA
TRAMESANPTSDLRGSAEYKKKMVKVLTKRAIITALKR
>Mature_278_residues
MYPPKFGYVIPDNLNEALEFLEEHQDARPLAGGHSLIPMLKLRLIRPSYIVEIRRFSNLSYITKDGNLYKIGALTTHYNI
SKSSIPLLSETASNIGDPQVRNMGTIGGSISHLDPSADYPAALIAMDAKVKITSRKGDRVVNFKSFAKDMFTPDLNPGEL
VTEIQVPTFEGYKFSYQKLERRAGDFAIVGVALLLKLSGDVIEDVRIGLTAVNNVAVRAKGAEEELLGKRLNDEIIEKAA
TRAMESANPTSDLRGSAEYKKKMVKVLTKRAIITALKR

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=277, Percent_Identity=22.0216606498195, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789231, Length=273, Percent_Identity=26.7399267399267, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 30710; Mature: 30710

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00061 ADH_SHORT ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPPKFGYVIPDNLNEALEFLEEHQDARPLAGGHSLIPMLKLRLIRPSYIVEIRRFSNLS
CCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCE
YITKDGNLYKIGALTTHYNISKSSIPLLSETASNIGDPQVRNMGTIGGSISHLDPSADYP
EEECCCCEEEEEEEEEEECCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCC
AALIAMDAKVKITSRKGDRVVNFKSFAKDMFTPDLNPGELVTEIQVPTFEGYKFSYQKLE
EEEEEECCEEEEECCCCCEEECHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
RRAGDFAIVGVALLLKLSGDVIEDVRIGLTAVNNVAVRAKGAEEELLGKRLNDEIIEKAA
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHH
TRAMESANPTSDLRGSAEYKKKMVKVLTKRAIITALKR
HHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYPPKFGYVIPDNLNEALEFLEEHQDARPLAGGHSLIPMLKLRLIRPSYIVEIRRFSNLS
CCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCE
YITKDGNLYKIGALTTHYNISKSSIPLLSETASNIGDPQVRNMGTIGGSISHLDPSADYP
EEECCCCEEEEEEEEEEECCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCC
AALIAMDAKVKITSRKGDRVVNFKSFAKDMFTPDLNPGELVTEIQVPTFEGYKFSYQKLE
EEEEEECCEEEEECCCCCEEECHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
RRAGDFAIVGVALLLKLSGDVIEDVRIGLTAVNNVAVRAKGAEEELLGKRLNDEIIEKAA
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHH
TRAMESANPTSDLRGSAEYKKKMVKVLTKRAIITALKR
HHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]