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The map label for this gene is cutS [H]

Identifier: 15920779

GI number: 15920779

Start: 552526

End: 553041

Strand: Reverse

Name: cutS [H]

Synonym: ST0561

Alternate gene names: 15920779

Gene position: 553041-552526 (Counterclockwise)

Preceding gene: 15920780

Following gene: 15920777

Centisome position: 20.52

GC content: 35.66

Gene sequence:

>516_bases
GTGAAACAGATGAAAATAATCAATAGTGATCAAAAAGTAAAAATTACATTAAAGATAAATGGCGAAAAGTATGAGACTGA
AGTTGAACCTAGAAGATTATTAGTTCATGTACTTAGAGAATTAGGATTTACTGGAGTACATATTGGTTGTGATACATCAA
ATTGTGGTGCTTGTACGGTAATTATGAACGGAAAATCAGTAAAATCATGCACAGTGCTTGCAGTAGAAGCAGATGGAGCA
GAAATACTTACAGTTGAAGGATTAGCTAAAGATGGAAAACTTCATCCAATACAAGAAGCTTTCTGGGAGAATCACGCATT
ACAATGTGGGTATTGCACCCCTGGTATGATAATGGAAGCTTATTGGCTACTTAGGGAAAAACCTAATCCAACAGAGGAAG
AAATAAGAGAAGGCATATCTGGGAACCTATGTAGATGTACTGGATATCAAAATATTGTAAAAGCTATTAAGGCTGCTGCA
GAGAAGTTAAGTCAGACTCCGTATCAACATCAGTAA

Upstream 100 bases:

>100_bases
AGAGTGCAAACCCCACTTCAGATTTAAGAGGCTCTGCTGAATATAAGAAAAAGATGGTAAAAGTTTTAACTAAGAGAGCT
ATTATTACAGCGTTAAAGAG

Downstream 100 bases:

>100_bases
CAACTTCTACTCCGCATTCAACAAAACATAAATCACTTCTCTTTTTCAATATTTCTCTTGCTCCTATATCTCCAGATAAT
GAAAAAACTTGTTCGTATAA

Product: dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKQMKIINSDQKVKITLKINGEKYETEVEPRRLLVHVLRELGFTGVHIGCDTSNCGACTVIMNGKSVKSCTVLAVEADGA
EILTVEGLAKDGKLHPIQEAFWENHALQCGYCTPGMIMEAYWLLREKPNPTEEEIREGISGNLCRCTGYQNIVKAIKAAA
EKLSQTPYQHQ

Sequences:

>Translated_171_residues
MKQMKIINSDQKVKITLKINGEKYETEVEPRRLLVHVLRELGFTGVHIGCDTSNCGACTVIMNGKSVKSCTVLAVEADGA
EILTVEGLAKDGKLHPIQEAFWENHALQCGYCTPGMIMEAYWLLREKPNPTEEEIREGISGNLCRCTGYQNIVKAIKAAA
EKLSQTPYQHQ
>Mature_171_residues
MKQMKIINSDQKVKITLKINGEKYETEVEPRRLLVHVLRELGFTGVHIGCDTSNCGACTVIMNGKSVKSCTVLAVEADGA
EILTVEGLAKDGKLHPIQEAFWENHALQCGYCTPGMIMEAYWLLREKPNPTEEEIREGISGNLCRCTGYQNIVKAIKAAA
EKLSQTPYQHQ

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=38.125, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI71773480, Length=161, Percent_Identity=32.9192546583851, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=43.9024390243902, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1789232, Length=153, Percent_Identity=46.4052287581699, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1789246, Length=149, Percent_Identity=28.8590604026846, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540638, Length=177, Percent_Identity=40.1129943502825, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=40.2597402597403, Blast_Score=125, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=38.961038961039, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI17737937, Length=163, Percent_Identity=34.3558282208589, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=33.5365853658537, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=33.5365853658537, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=36.0759493670886, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=35.625, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=35.0649350649351, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 19007; Mature: 19007

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQMKIINSDQKVKITLKINGEKYETEVEPRRLLVHVLRELGFTGVHIGCDTSNCGACTV
CCCCEEECCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEE
IMNGKSVKSCTVLAVEADGAEILTVEGLAKDGKLHPIQEAFWENHALQCGYCTPGMIMEA
EECCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEECCCCCHHHHHH
YWLLREKPNPTEEEIREGISGNLCRCTGYQNIVKAIKAAAEKLSQTPYQHQ
HHHHHCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQMKIINSDQKVKITLKINGEKYETEVEPRRLLVHVLRELGFTGVHIGCDTSNCGACTV
CCCCEEECCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEE
IMNGKSVKSCTVLAVEADGAEILTVEGLAKDGKLHPIQEAFWENHALQCGYCTPGMIMEA
EECCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEECCCCCHHHHHH
YWLLREKPNPTEEEIREGISGNLCRCTGYQNIVKAIKAAAEKLSQTPYQHQ
HHHHHCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]