Click here to switch to the map view.

The map label for this gene is moaC

Identifier: 15920688

GI number: 15920688

Start: 474544

End: 474999

Strand: Direct

Name: moaC

Synonym: ST0472

Alternate gene names: 15920688

Gene position: 474544-474999 (Clockwise)

Preceding gene: 15920687

Following gene: 15920695

Centisome position: 17.61

GC content: 30.7

Gene sequence:

>456_bases
ATGACTGAAGCAAAAATAGTAGATATTTCATCTAAGGATATAGTTCTAAGGGAAGCTGTGGTAGAAGGTTATATAAAATT
AAGAAAAGAAACAATAGAAAAAATTAAAAATAAAGAAGTTGAAAAAGGCGATGTAATTACTGTAGCTAAAACAGCTGGAA
TATTAGCTGCTAAAAAAACTCCAGAATTAATACCAATGTGTCACCCAATACCTTTAGAGTTTGTTGATGTAGAAATTAAA
ATTGAAGAAGAAGGATTAAGAGTAATAAGTACTGTTAAGGCTCATTATAAGACTGGTGTTGAAATGGAAGCACTAACCGC
AACTTCAGTGGCTCTTCTTACTATTTGGGACATGGTTAAAAAGTATGAAAAAGATGAAAATGGACAGTATCCTTATACTG
AGATAAAGTCAATTAGGGTTATTAATAAAATTAAGACTTACGACGATATGAAGTAG

Upstream 100 bases:

>100_bases
TTGAAGTAATAAGAGGAGATAGAAGCAAAATAATCAGATTAAACTATGCTAATCCTAAAGTAATAATTTTAAAAAATTTG
TTTGAGGAATTAGAAGATAT

Downstream 100 bases:

>100_bases
TTCTTCTTTTACTTGGTTCTTTTTTCTCTGGTTCTTCTATTTCCACTTTACTTCCTTCGTAGAATGAAGAAATTAACTTA
ATAACATCTTTTTCTTTTTC

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTEAKIVDISSKDIVLREAVVEGYIKLRKETIEKIKNKEVEKGDVITVAKTAGILAAKKTPELIPMCHPIPLEFVDVEIK
IEEEGLRVISTVKAHYKTGVEMEALTATSVALLTIWDMVKKYEKDENGQYPYTEIKSIRVINKIKTYDDMK

Sequences:

>Translated_151_residues
MTEAKIVDISSKDIVLREAVVEGYIKLRKETIEKIKNKEVEKGDVITVAKTAGILAAKKTPELIPMCHPIPLEFVDVEIK
IEEEGLRVISTVKAHYKTGVEMEALTATSVALLTIWDMVKKYEKDENGQYPYTEIKSIRVINKIKTYDDMK
>Mature_150_residues
TEAKIVDISSKDIVLREAVVEGYIKLRKETIEKIKNKEVEKGDVITVAKTAGILAAKKTPELIPMCHPIPLEFVDVEIKI
EEEGLRVISTVKAHYKTGVEMEALTATSVALLTIWDMVKKYEKDENGQYPYTEIKSIRVINKIKTYDDMK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=125, Percent_Identity=48, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566331, Length=119, Percent_Identity=52.1008403361345, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI28574492, Length=122, Percent_Identity=44.2622950819672, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574490, Length=125, Percent_Identity=44, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_SULTO (Q975D5)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376357.1
- PDB:   2OHD
- PDBsum:   2OHD
- ProteinModelPortal:   Q975D5
- SMR:   Q975D5
- GeneID:   1458415
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0472
- NMPDR:   fig|273063.1.peg.525
- HOGENOM:   HBG605231
- OMA:   RIKEGTI
- ProtClustDB:   PRK12343
- BioCyc:   STOK273063:ST0472-MONOMER
- HAMAP:   MF_01224_A
- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17125; Mature: 16994

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAKIVDISSKDIVLREAVVEGYIKLRKETIEKIKNKEVEKGDVITVAKTAGILAAKKT
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCC
PELIPMCHPIPLEFVDVEIKIEEEGLRVISTVKAHYKTGVEMEALTATSVALLTIWDMVK
CCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
KYEKDENGQYPYTEIKSIRVINKIKTYDDMK
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEAKIVDISSKDIVLREAVVEGYIKLRKETIEKIKNKEVEKGDVITVAKTAGILAAKKT
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCC
PELIPMCHPIPLEFVDVEIKIEEEGLRVISTVKAHYKTGVEMEALTATSVALLTIWDMVK
CCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
KYEKDENGQYPYTEIKSIRVINKIKTYDDMK
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479