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The map label for this gene is cdc6

Identifier: 15920687

GI number: 15920687

Start: 473052

End: 474308

Strand: Direct

Name: cdc6

Synonym: ST0471

Alternate gene names: 15920687

Gene position: 473052-474308 (Clockwise)

Preceding gene: 15920686

Following gene: 15920688

Centisome position: 17.55

GC content: 31.74

Gene sequence:

>1257_bases
GTGAAAGTTTTGGATGAGCTAAGAGATTTGGTTGAGGATGCAATTAAGGGCTCAACAGTATTCGAGAAAAGCAAAGTTTT
AACACCAGATTATATTCCTAAGAACTTGCCTCACAGAGAAAAACAGATAAAGGAGTTAAGTATAAATTTCAGAGAAATTC
TTTCAAACCCTGGGAGTACATCAGTTAGAGTAGTAATTTCTGGTAAGACTGGTACTGGTAAAACTGTTACGACAAAAAAG
TTTGGAGAGCTTTTTAGTGAAATTGCAAAAGAGAAGGGGCTTAGAGTTGTTTATACTCATATAAATTGTCATAGACAAAG
AACTCTTTACCTTATGCTAGTTGAAATTGCAAATCAGTTAAATTTGCAGATACCTAATAGAGGTTTATCATCACAAGAAA
CCTTTAAGTTAATATATGATTACCTAGAAAAAAGAAACATTCAACTAATAATTACATTAGATGAATTTGATTATTTTGTA
AGTACCTCACCAGTTGAAGACATTTATTTTCTAGTGAGGATATATGATGAACTTAACGCTTTAGTAAAACGCATTCACTA
CATTTTCATTCTGAGAGAACTGACTAGTTTAGCAAGCTTAGACAAGAGTATAAAAGATCACGTGATAAAGAATGTTATAG
AGTTTCCCCCGTATACTTCTGAGGAATTGTATGATATTTTAATGGATAGGATAGTAAATGAGAAAGCATTCAGAGAAGGA
GCTGTCTTAGAAGAGACTGTAAGATTCATTTCAGATATTTATGGTATTGATAAAGGTGGAAGTGGTAATGCAAGACTTGC
GCTTGAAACACTAGAGCTTGCTGGCAAGATTGCGGATACGGAAGGTTCATTATTAGTAACTATTGATCATGCTAAAAAGG
CTAATTCAAAAATTAACCCTGAATTAAGTATAATCTTAGATACGATAAGAGATTTAGATTTACATCAACTATTAGTAGTT
AAGGCTATAATGAATTTACATAAAAAGGAAGGAGATGATTTCTTCTCAATGGGAAAAGTAGAAGAAGAATATAATATTGT
AGCAAAAGATCTAGGAGAAATACCTAGGAAACATACGCAAGTTTTTGAATATATAAGAAAGTTAAAATTAATGGGTTTAA
TAACAGCTAGGCAAAGCGGTAAAGGAATGCGAGGTAGAACAACTCTTATATCTCTTTCAGTTCCTATATCAGAAGAATTA
GATAATCTAATTAATAATGAAATAAGGGATAGACTATTACAGCAAAAGAACTATTAA

Upstream 100 bases:

>100_bases
GACTCTACCTATATGTCGGTAATTAAAAAGGGTCAAGAAAAAGTTTCAGTTATCTCTCTCCGTTAAAATATATAGTATTA
CCAGAATATTTTAGATTGAG

Downstream 100 bases:

>100_bases
ATCCTAGTATTTTAAAAATTCTTTATATTTTATTTAAGGAAGGAGAGATAAACATAAGTAAACTAGCTAAGGAAACTAAA
TTAAACTATTCTACTTTACT

Product: cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog 2

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKVLDELRDLVEDAIKGSTVFEKSKVLTPDYIPKNLPHREKQIKELSINFREILSNPGSTSVRVVISGKTGTGKTVTTKK
FGELFSEIAKEKGLRVVYTHINCHRQRTLYLMLVEIANQLNLQIPNRGLSSQETFKLIYDYLEKRNIQLIITLDEFDYFV
STSPVEDIYFLVRIYDELNALVKRIHYIFILRELTSLASLDKSIKDHVIKNVIEFPPYTSEELYDILMDRIVNEKAFREG
AVLEETVRFISDIYGIDKGGSGNARLALETLELAGKIADTEGSLLVTIDHAKKANSKINPELSIILDTIRDLDLHQLLVV
KAIMNLHKKEGDDFFSMGKVEEEYNIVAKDLGEIPRKHTQVFEYIRKLKLMGLITARQSGKGMRGRTTLISLSVPISEEL
DNLINNEIRDRLLQQKNY

Sequences:

>Translated_418_residues
MKVLDELRDLVEDAIKGSTVFEKSKVLTPDYIPKNLPHREKQIKELSINFREILSNPGSTSVRVVISGKTGTGKTVTTKK
FGELFSEIAKEKGLRVVYTHINCHRQRTLYLMLVEIANQLNLQIPNRGLSSQETFKLIYDYLEKRNIQLIITLDEFDYFV
STSPVEDIYFLVRIYDELNALVKRIHYIFILRELTSLASLDKSIKDHVIKNVIEFPPYTSEELYDILMDRIVNEKAFREG
AVLEETVRFISDIYGIDKGGSGNARLALETLELAGKIADTEGSLLVTIDHAKKANSKINPELSIILDTIRDLDLHQLLVV
KAIMNLHKKEGDDFFSMGKVEEEYNIVAKDLGEIPRKHTQVFEYIRKLKLMGLITARQSGKGMRGRTTLISLSVPISEEL
DNLINNEIRDRLLQQKNY
>Mature_418_residues
MKVLDELRDLVEDAIKGSTVFEKSKVLTPDYIPKNLPHREKQIKELSINFREILSNPGSTSVRVVISGKTGTGKTVTTKK
FGELFSEIAKEKGLRVVYTHINCHRQRTLYLMLVEIANQLNLQIPNRGLSSQETFKLIYDYLEKRNIQLIITLDEFDYFV
STSPVEDIYFLVRIYDELNALVKRIHYIFILRELTSLASLDKSIKDHVIKNVIEFPPYTSEELYDILMDRIVNEKAFREG
AVLEETVRFISDIYGIDKGGSGNARLALETLELAGKIADTEGSLLVTIDHAKKANSKINPELSIILDTIRDLDLHQLLVV
KAIMNLHKKEGDDFFSMGKVEEEYNIVAKDLGEIPRKHTQVFEYIRKLKLMGLITARQSGKGMRGRTTLISLSVPISEEL
DNLINNEIRDRLLQQKNY

Specific function: Might be involved in the initiation of DNA replication

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family

Homologues:

Organism=Homo sapiens, GI4502703, Length=388, Percent_Identity=21.6494845360825, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDC62_SULTO (Q975D6)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376356.1
- ProteinModelPortal:   Q975D6
- SMR:   Q975D6
- GeneID:   1458414
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0471
- NMPDR:   fig|273063.1.peg.524
- HOGENOM:   HBG553472
- OMA:   IPFPRRG
- ProtClustDB:   PRK00411
- BioCyc:   STOK273063:ST0471-MONOMER
- HAMAP:   MF_01407
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10763:SF8
- TIGRFAMs:   TIGR02928

Pfam domain/function: PF09079 Cdc6_C

EC number: NA

Molecular weight: Translated: 47846; Mature: 47846

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLDELRDLVEDAIKGSTVFEKSKVLTPDYIPKNLPHREKQIKELSINFREILSNPGST
CCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCC
SVRVVISGKTGTGKTVTTKKFGELFSEIAKEKGLRVVYTHINCHRQRTLYLMLVEIANQL
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHC
NLQIPNRGLSSQETFKLIYDYLEKRNIQLIITLDEFDYFVSTSPVEDIYFLVRIYDELNA
CEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHH
LVKRIHYIFILRELTSLASLDKSIKDHVIKNVIEFPPYTSEELYDILMDRIVNEKAFREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
AVLEETVRFISDIYGIDKGGSGNARLALETLELAGKIADTEGSLLVTIDHAKKANSKINP
HHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
ELSIILDTIRDLDLHQLLVVKAIMNLHKKEGDDFFSMGKVEEEYNIVAKDLGEIPRKHTQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCHHHHH
VFEYIRKLKLMGLITARQSGKGMRGRTTLISLSVPISEELDNLINNEIRDRLLQQKNY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVLDELRDLVEDAIKGSTVFEKSKVLTPDYIPKNLPHREKQIKELSINFREILSNPGST
CCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCC
SVRVVISGKTGTGKTVTTKKFGELFSEIAKEKGLRVVYTHINCHRQRTLYLMLVEIANQL
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHC
NLQIPNRGLSSQETFKLIYDYLEKRNIQLIITLDEFDYFVSTSPVEDIYFLVRIYDELNA
CEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHH
LVKRIHYIFILRELTSLASLDKSIKDHVIKNVIEFPPYTSEELYDILMDRIVNEKAFREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
AVLEETVRFISDIYGIDKGGSGNARLALETLELAGKIADTEGSLLVTIDHAKKANSKINP
HHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
ELSIILDTIRDLDLHQLLVVKAIMNLHKKEGDDFFSMGKVEEEYNIVAKDLGEIPRKHTQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCHHHHH
VFEYIRKLKLMGLITARQSGKGMRGRTTLISLSVPISEELDNLINNEIRDRLLQQKNY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479