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The map label for this gene is rio2 [H]

Identifier: 15920414

GI number: 15920414

Start: 253059

End: 253925

Strand: Direct

Name: rio2 [H]

Synonym: ST0233

Alternate gene names: 15920414

Gene position: 253059-253925 (Clockwise)

Preceding gene: 15920412

Following gene: 15920415

Centisome position: 9.39

GC content: 27.45

Gene sequence:

>867_bases
ATGGCTGTTTTAACATTAGCAGAAAGAGCCTCTCTAGTAGGACCCCTTGATTATAAAGTTTTGAAAACTATTTACGAATT
AAATTCTAATTATGAATATGTTCCATATTCTGTAATAATAAACAAACTAGGATTATTAGAAAGAGAACTTAAAGAGGTTC
TTCTAAAATTATACAATCTAAAGCTCGTATCTAAAGAAAAAGTATTGAAAGAAACAGGGTACAGAATTACTTTCGCTGGC
TTAGATACTTTAGCAATTAAAAAATTATATGCTAATAAAGTACTAAATAAATTAGGAATAATAATAGGTGAAGGAAAAGA
AAGTAATGTCTACTTTGGATATGATTTCTCAGATGAAACAATAATAGTAAAATTCCATAGAGTAGGCAGAACTAGTTACA
AAAATATAAGAAAAATACGTGGAATAAAATATAAAGAAGATTGGATAAAATTAACAATAGAAAATGCTGAAAGAGAATTT
AGCGCATTAAGTTGCCTTACTAATAATTATGCAAACGTTCCTAAACCGTTAGGTCAAGCTTACAATGCTGTTGCTATGGA
ATATATTCAAGGTAATGAATTATATAGAACTAATTTGAATAACCCAGAGGAAGTATTAGAAGAAATAATCTCTAATGTCA
GAATTGCATACCAATACTGCGGCAAGTTAGTACACGGCGATTTAAGTGAATATAACATATTAATAAGAGAGGATGGTAAG
CCATATATTATAGATTGGCCCCAATGGAAAAAAGATGATGAAGACTTATTATTTAGAGATCTAACAAATATATTATATTA
CTTTAATAAAAAATATGAAATATATAAAGATATTGATCAAGTAATAAATTATATAAAGGGGGAATAA

Upstream 100 bases:

>100_bases
CGAACATTACAAGATGACATAATAAGATCTCTTCCTGGTAAAAGCAAAATAGTAGCAATAAAGAATAAAACTTAGGATTT
GTAATATTAAGTTAAACATT

Downstream 100 bases:

>100_bases
TGCGGGTATTAGGCGTAGATATAGAAGCGGGGAAAAGCCCTAATTCCTCTCAACCACCTTCTTATGCAGTAGTAATTATT
AATGAAAAAGGAGAAATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: AfRio2 [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAVLTLAERASLVGPLDYKVLKTIYELNSNYEYVPYSVIINKLGLLERELKEVLLKLYNLKLVSKEKVLKETGYRITFAG
LDTLAIKKLYANKVLNKLGIIIGEGKESNVYFGYDFSDETIIVKFHRVGRTSYKNIRKIRGIKYKEDWIKLTIENAEREF
SALSCLTNNYANVPKPLGQAYNAVAMEYIQGNELYRTNLNNPEEVLEEIISNVRIAYQYCGKLVHGDLSEYNILIREDGK
PYIIDWPQWKKDDEDLLFRDLTNILYYFNKKYEIYKDIDQVINYIKGE

Sequences:

>Translated_288_residues
MAVLTLAERASLVGPLDYKVLKTIYELNSNYEYVPYSVIINKLGLLERELKEVLLKLYNLKLVSKEKVLKETGYRITFAG
LDTLAIKKLYANKVLNKLGIIIGEGKESNVYFGYDFSDETIIVKFHRVGRTSYKNIRKIRGIKYKEDWIKLTIENAEREF
SALSCLTNNYANVPKPLGQAYNAVAMEYIQGNELYRTNLNNPEEVLEEIISNVRIAYQYCGKLVHGDLSEYNILIREDGK
PYIIDWPQWKKDDEDLLFRDLTNILYYFNKKYEIYKDIDQVINYIKGE
>Mature_287_residues
AVLTLAERASLVGPLDYKVLKTIYELNSNYEYVPYSVIINKLGLLERELKEVLLKLYNLKLVSKEKVLKETGYRITFAGL
DTLAIKKLYANKVLNKLGIIIGEGKESNVYFGYDFSDETIIVKFHRVGRTSYKNIRKIRGIKYKEDWIKLTIENAEREFS
ALSCLTNNYANVPKPLGQAYNAVAMEYIQGNELYRTNLNNPEEVLEEIISNVRIAYQYCGKLVHGDLSEYNILIREDGKP
YIIDWPQWKKDDEDLLFRDLTNILYYFNKKYEIYKDIDQVINYIKGE

Specific function: Unknown

COG id: COG0478

COG function: function code T; RIO-like serine/threonine protein kinase fused to N-terminal HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI229331971, Length=267, Percent_Identity=30.7116104868914, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI229331967, Length=267, Percent_Identity=30.7116104868914, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32564178, Length=265, Percent_Identity=30.188679245283, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324122, Length=272, Percent_Identity=30.1470588235294, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24649986, Length=265, Percent_Identity=31.3207547169811, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33640; Mature: 33509

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLTLAERASLVGPLDYKVLKTIYELNSNYEYVPYSVIINKLGLLERELKEVLLKLYNL
CCEEEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KLVSKEKVLKETGYRITFAGLDTLAIKKLYANKVLNKLGIIIGEGKESNVYFGYDFSDET
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCCCE
IIVKFHRVGRTSYKNIRKIRGIKYKEDWIKLTIENAEREFSALSCLTNNYANVPKPLGQA
EEEEEECCCCHHHHHHHHHCCCCEECCEEEEEEECHHHHHHHHHHHHCCCCCCCHHHHHH
YNAVAMEYIQGNELYRTNLNNPEEVLEEIISNVRIAYQYCGKLVHGDLSEYNILIREDGK
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
PYIIDWPQWKKDDEDLLFRDLTNILYYFNKKYEIYKDIDQVINYIKGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVLTLAERASLVGPLDYKVLKTIYELNSNYEYVPYSVIINKLGLLERELKEVLLKLYNL
CEEEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KLVSKEKVLKETGYRITFAGLDTLAIKKLYANKVLNKLGIIIGEGKESNVYFGYDFSDET
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCCCE
IIVKFHRVGRTSYKNIRKIRGIKYKEDWIKLTIENAEREFSALSCLTNNYANVPKPLGQA
EEEEEECCCCHHHHHHHHHCCCCEECCEEEEEEECHHHHHHHHHHHHCCCCCCCHHHHHH
YNAVAMEYIQGNELYRTNLNNPEEVLEEIISNVRIAYQYCGKLVHGDLSEYNILIREDGK
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
PYIIDWPQWKKDDEDLLFRDLTNILYYFNKKYEIYKDIDQVINYIKGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]