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The map label for this gene is galE [C]

Identifier: 15920365

GI number: 15920365

Start: 210549

End: 211469

Strand: Direct

Name: galE [C]

Synonym: ST0187

Alternate gene names: 15920365

Gene position: 210549-211469 (Clockwise)

Preceding gene: 15920364

Following gene: 15920375

Centisome position: 7.81

GC content: 31.27

Gene sequence:

>921_bases
ATGGTTTACGTGATAACTGGTGGTGCTGGTTATATAGGTGGGCATTTAACAGATTATTTAGTAGAAAGAGGAGAAGATGT
CGTTGTAATTGATGATTTTTCTTATGGAAAATATATGAATAATAAAGCTATTTATAAAAAGATAGATTTAAGATCTAATG
CTGACATAGAAATACCAAAAGATTCAATTCTTTTTCATTTAGCTGCCAATCCAGATGTAAGGACTTCAATGATTCACGTG
CAAGAACATTTTGAAAGGGATGTAAAGGTTACTCTTAATATATTAGAAATAGCGAGAAAATATGATGTTAAAAAATTTAT
CTTTGCCTCTTCCTCTACTGTATATGGAGAGGCAAAAGTTATTCCTACACCAGAAGATTCTGAATTAAAGCCAATTTCTA
ACTATGGTCTTTTTAAATTATTAGGAGAAGAAATGGTAGAATATTATTCTAGGGTTTATAGTATAAGAGCAGTTTCGGTT
CGTTTAGCTAACGTAACTGGAGGTAGAATATCTCATGGAGTAATTTATGATTTCGTAAATAAACTCTTAAAAGATAGTAA
TAAGCTAGAAATTTTAGGAAATGGAAAACAGAAAAAAAGTTATATCTATATTACAGATACAATAGAAGGATTAATCTTAT
TAGCAGAGGAAAATACTGGTTCGTATTCAGTATATAATCTTGGTAACGAAGATTGGATTACTGTTGATGAAATTGCTAAG
ATCGTGGAAGAGGAAATGGGTGTGTCCCCCAAGCATATATACGTTGATTCTGGAGAAGGAAGAGGATGGGTGGGTGATGT
TAGATTTATGTTACTTGACATAAAAAAGATAAAAGAAATTGGTTGGAAGCCTAAATATACTTCTAGAGACGCTGTTAGAC
TTGCTGTGAGGGATTTATTAAATGAATTACATAAAAATTAG

Upstream 100 bases:

>100_bases
AATGCATGAAAAAGCTATAATGTTTGATAAAAATAACTTCAAGGAAAAAATTTACGACGTTATAAGTAAATATTTAATGT
AGAGTATTTTATTATTTTCC

Downstream 100 bases:

>100_bases
GCTGCTAGGCTTAGGTTTGCTTCTTCTCTCTATAACTATAATAATATTATCCTTTGAAATATTATTTCTAGGATTACAGA
TAAAACTCGGTAATTTTAGA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVYVITGGAGYIGGHLTDYLVERGEDVVVIDDFSYGKYMNNKAIYKKIDLRSNADIEIPKDSILFHLAANPDVRTSMIHV
QEHFERDVKVTLNILEIARKYDVKKFIFASSSTVYGEAKVIPTPEDSELKPISNYGLFKLLGEEMVEYYSRVYSIRAVSV
RLANVTGGRISHGVIYDFVNKLLKDSNKLEILGNGKQKKSYIYITDTIEGLILLAEENTGSYSVYNLGNEDWITVDEIAK
IVEEEMGVSPKHIYVDSGEGRGWVGDVRFMLLDIKKIKEIGWKPKYTSRDAVRLAVRDLLNELHKN

Sequences:

>Translated_306_residues
MVYVITGGAGYIGGHLTDYLVERGEDVVVIDDFSYGKYMNNKAIYKKIDLRSNADIEIPKDSILFHLAANPDVRTSMIHV
QEHFERDVKVTLNILEIARKYDVKKFIFASSSTVYGEAKVIPTPEDSELKPISNYGLFKLLGEEMVEYYSRVYSIRAVSV
RLANVTGGRISHGVIYDFVNKLLKDSNKLEILGNGKQKKSYIYITDTIEGLILLAEENTGSYSVYNLGNEDWITVDEIAK
IVEEEMGVSPKHIYVDSGEGRGWVGDVRFMLLDIKKIKEIGWKPKYTSRDAVRLAVRDLLNELHKN
>Mature_306_residues
MVYVITGGAGYIGGHLTDYLVERGEDVVVIDDFSYGKYMNNKAIYKKIDLRSNADIEIPKDSILFHLAANPDVRTSMIHV
QEHFERDVKVTLNILEIARKYDVKKFIFASSSTVYGEAKVIPTPEDSELKPISNYGLFKLLGEEMVEYYSRVYSIRAVSV
RLANVTGGRISHGVIYDFVNKLLKDSNKLEILGNGKQKKSYIYITDTIEGLILLAEENTGSYSVYNLGNEDWITVDEIAK
IVEEEMGVSPKHIYVDSGEGRGWVGDVRFMLLDIKKIKEIGWKPKYTSRDAVRLAVRDLLNELHKN

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=27.7070063694268, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=27.1875, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=318, Percent_Identity=25.7861635220126, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=25.3687315634218, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788353, Length=349, Percent_Identity=24.9283667621776, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=318, Percent_Identity=26.7295597484277, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115532424, Length=336, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=351, Percent_Identity=25.3561253561254, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982038, Length=353, Percent_Identity=25.2124645892351, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568069, Length=267, Percent_Identity=24.7191011235955, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=27.5964391691395, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356223, Length=321, Percent_Identity=27.4143302180685, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI19923002, Length=324, Percent_Identity=26.2345679012346, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34702; Mature: 34702

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYVITGGAGYIGGHLTDYLVERGEDVVVIDDFSYGKYMNNKAIYKKIDLRSNADIEIPK
CEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEECC
DSILFHLAANPDVRTSMIHVQEHFERDVKVTLNILEIARKYDVKKFIFASSSTVYGEAKV
CCEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHEEEECCCEEECCEEE
IPTPEDSELKPISNYGLFKLLGEEMVEYYSRVYSIRAVSVRLANVTGGRISHGVIYDFVN
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCHHHHHHHH
KLLKDSNKLEILGNGKQKKSYIYITDTIEGLILLAEENTGSYSVYNLGNEDWITVDEIAK
HHHCCCCCEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCEEEEECCCCCCEEHHHHHH
IVEEEMGVSPKHIYVDSGEGRGWVGDVRFMLLDIKKIKEIGWKPKYTSRDAVRLAVRDLL
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
NELHKN
HHHHCC
>Mature Secondary Structure
MVYVITGGAGYIGGHLTDYLVERGEDVVVIDDFSYGKYMNNKAIYKKIDLRSNADIEIPK
CEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEECC
DSILFHLAANPDVRTSMIHVQEHFERDVKVTLNILEIARKYDVKKFIFASSSTVYGEAKV
CCEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHEEEECCCEEECCEEE
IPTPEDSELKPISNYGLFKLLGEEMVEYYSRVYSIRAVSVRLANVTGGRISHGVIYDFVN
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCHHHHHHHH
KLLKDSNKLEILGNGKQKKSYIYITDTIEGLILLAEENTGSYSVYNLGNEDWITVDEIAK
HHHCCCCCEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCEEEEECCCCCCEEHHHHHH
IVEEEMGVSPKHIYVDSGEGRGWVGDVRFMLLDIKKIKEIGWKPKYTSRDAVRLAVRDLL
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
NELHKN
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]