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The map label for this gene is mmgC [H]

Identifier: 15920255

GI number: 15920255

Start: 98607

End: 99809

Strand: Direct

Name: mmgC [H]

Synonym: ST0076

Alternate gene names: 15920255

Gene position: 98607-99809 (Clockwise)

Preceding gene: 15920254

Following gene: 15920256

Centisome position: 3.66

GC content: 39.4

Gene sequence:

>1203_bases
ATGGTCTTGCCTTTTAAGTCAGCAGAAGTCTTCTCTGTGGAAGTTTCAGAAAAACATGAATTGTTTAGAAAAGCTGTAAG
AGAGTTTATGGAGAGAGATGTGGCTCCTTATGTGGAAAAAGGGGAGGCACAGAGAGAAGTACCTAAAGAAATATTAGAAA
AAGCGAAGGAGTTAGGTCTCTATGGTATAACTGTCCCGGAAGAATACGGAGGCCAAGGAGGAGATACTTTAATGTCTGCA
ATAGCTCAGGAAGAAATATCTAGAATATGGCCTTCTTTTGCTACAAGAGTTGCCGCTGGTGCCTTATTTACAACTCCGAT
ATTGCTTTTTGGGTCAGAGGAGTTAAAGAAGAAATACGTTCCTCCAGTTGCGAGAGGAGAAAAAGTTGCAGCATTAGCAA
ATACTGAGCCTAGTGCTGGATCTGATGTTGCTGGAATGCAGAGTACCGCAAAGAAAATTAATGGAAAATACATACTTAAT
GGAAGAAAAATCTTCATAACTAATGGTGGCATAGCAGATTATTACGTTGTTACTGCAAGAACTTCTCCACCAGATCCTAA
AGCTAGATGGAAAGGAATTTCAATGTTCGTAGTGGAGAGAGAATGGAAAGGAGTTAAAGTTGTTAGTAGAATCGATACCT
TAGGATTAAAGGCTTCAAATACTGCAGAATTAATATTCGAAGATGTAGAAATACCAGAGGAGAATGTTGTAGGTGAGGAG
GGAAACGGTTTTAAATATGCAATGGCAACTTTCGATAGAACTAGGGTTGGGGTTGCAGCACAAGCATTAGGTGTTGCTCA
AGCCGCTCTAGAGAAAATGGTAAGTTATGCCAGCCAACGTATAGCATTTGGAGAACCTATAGTAATGTTTGAGTTGGTCC
AAGAAAAGATTGCTGAGTCGTTAACGGAAGTGAATACTGCGAGACTTCTCACTTATTGGGCGGCTACTCTTTTTGATAAA
GGATTAGAGAACGAGGCTATAGTAGCTGCTTCAATGGCAAAATATTATTCTACTGAGATAGCCGAGAAAGTGGTAATTAG
GGCTATTACTGTACATGGAGGCTATGGCGTTGCAACTTCTACTGGAGTTGAAAGATTGCTAAGGGATGTAGAGGTTATGA
AAATTTATGAAGGAACAAATGATATACAGAAACTTACTATAGTTAAGGAGACAGCGAGAAGGCTATTGGGTATTAAATTA
TAA

Upstream 100 bases:

>100_bases
AGCTTACATGGATTTAGTAAATAGGAAGGTTTTTGGAAGAGCTGTACTAAAAATTAGATAAGATAAGAAAGTTTTTATTT
ATAAGCTGTTATATGTAATT

Downstream 100 bases:

>100_bases
TTAATTAGTTTGGGTAAAAAGATTTATTAATTGTCAATTCAATTTTCATTATATGAGTGAATATTACGAATATGAATTAA
CAATAGATAAGATTCTAGAT

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MVLPFKSAEVFSVEVSEKHELFRKAVREFMERDVAPYVEKGEAQREVPKEILEKAKELGLYGITVPEEYGGQGGDTLMSA
IAQEEISRIWPSFATRVAAGALFTTPILLFGSEELKKKYVPPVARGEKVAALANTEPSAGSDVAGMQSTAKKINGKYILN
GRKIFITNGGIADYYVVTARTSPPDPKARWKGISMFVVEREWKGVKVVSRIDTLGLKASNTAELIFEDVEIPEENVVGEE
GNGFKYAMATFDRTRVGVAAQALGVAQAALEKMVSYASQRIAFGEPIVMFELVQEKIAESLTEVNTARLLTYWAATLFDK
GLENEAIVAASMAKYYSTEIAEKVVIRAITVHGGYGVATSTGVERLLRDVEVMKIYEGTNDIQKLTIVKETARRLLGIKL

Sequences:

>Translated_400_residues
MVLPFKSAEVFSVEVSEKHELFRKAVREFMERDVAPYVEKGEAQREVPKEILEKAKELGLYGITVPEEYGGQGGDTLMSA
IAQEEISRIWPSFATRVAAGALFTTPILLFGSEELKKKYVPPVARGEKVAALANTEPSAGSDVAGMQSTAKKINGKYILN
GRKIFITNGGIADYYVVTARTSPPDPKARWKGISMFVVEREWKGVKVVSRIDTLGLKASNTAELIFEDVEIPEENVVGEE
GNGFKYAMATFDRTRVGVAAQALGVAQAALEKMVSYASQRIAFGEPIVMFELVQEKIAESLTEVNTARLLTYWAATLFDK
GLENEAIVAASMAKYYSTEIAEKVVIRAITVHGGYGVATSTGVERLLRDVEVMKIYEGTNDIQKLTIVKETARRLLGIKL
>Mature_400_residues
MVLPFKSAEVFSVEVSEKHELFRKAVREFMERDVAPYVEKGEAQREVPKEILEKAKELGLYGITVPEEYGGQGGDTLMSA
IAQEEISRIWPSFATRVAAGALFTTPILLFGSEELKKKYVPPVARGEKVAALANTEPSAGSDVAGMQSTAKKINGKYILN
GRKIFITNGGIADYYVVTARTSPPDPKARWKGISMFVVEREWKGVKVVSRIDTLGLKASNTAELIFEDVEIPEENVVGEE
GNGFKYAMATFDRTRVGVAAQALGVAQAALEKMVSYASQRIAFGEPIVMFELVQEKIAESLTEVNTARLLTYWAATLFDK
GLENEAIVAASMAKYYSTEIAEKVVIRAITVHGGYGVATSTGVERLLRDVEVMKIYEGTNDIQKLTIVKETARRLLGIKL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=40.2088772845953, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=37.007874015748, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=37.007874015748, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=35.3723404255319, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=35.7333333333333, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI21361497, Length=389, Percent_Identity=37.5321336760925, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=35.8839050131926, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI76496475, Length=398, Percent_Identity=36.4321608040201, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI4557235, Length=398, Percent_Identity=36.4321608040201, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=37.5358166189112, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=31.7460317460317, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI4503943, Length=383, Percent_Identity=29.242819843342, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=28.808864265928, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI48976061, Length=393, Percent_Identity=26.2086513994911, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI211971008, Length=393, Percent_Identity=26.2086513994911, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI38505218, Length=395, Percent_Identity=26.3291139240506, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=32.1052631578947, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87081958, Length=372, Percent_Identity=32.258064516129, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI87082384, Length=297, Percent_Identity=23.5690235690236, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081702, Length=365, Percent_Identity=22.4657534246575, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=38.1333333333333, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17538396, Length=369, Percent_Identity=37.3983739837398, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17569725, Length=386, Percent_Identity=35.7512953367876, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=36.1477572559367, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=32.6259946949602, Blast_Score=227, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=33.2446808510638, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71985184, Length=354, Percent_Identity=35.5932203389831, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=367, Percent_Identity=31.8801089918256, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=30.8093994778068, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=35.7142857142857, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=391, Percent_Identity=29.6675191815857, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=310, Percent_Identity=33.2258064516129, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=283, Percent_Identity=32.8621908127208, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=34.468085106383, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17534353, Length=387, Percent_Identity=28.4237726098191, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=34.4262295081967, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=404, Percent_Identity=27.4752475247525, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=33.1460674157303, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=312, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=312, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=39.0374331550802, Blast_Score=264, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=37.8947368421053, Blast_Score=250, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=35.9580052493438, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=34.8404255319149, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI281363737, Length=395, Percent_Identity=36.4556962025316, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=33.420365535248, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=29.5514511873351, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24652780, Length=343, Percent_Identity=23.9067055393586, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43921; Mature: 43921

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPFKSAEVFSVEVSEKHELFRKAVREFMERDVAPYVEKGEAQREVPKEILEKAKELGL
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCE
YGITVPEEYGGQGGDTLMSAIAQEEISRIWPSFATRVAAGALFTTPILLFGSEELKKKYV
EEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHCC
PPVARGEKVAALANTEPSAGSDVAGMQSTAKKINGKYILNGRKIFITNGGIADYYVVTAR
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCEEEEEECCCCEEEEEEEEC
TSPPDPKARWKGISMFVVEREWKGVKVVSRIDTLGLKASNTAELIFEDVEIPEENVVGEE
CCCCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHEECCCCCHHHCCCCC
GNGFKYAMATFDRTRVGVAAQALGVAQAALEKMVSYASQRIAFGEPIVMFELVQEKIAES
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LTEVNTARLLTYWAATLFDKGLENEAIVAASMAKYYSTEIAEKVVIRAITVHGGYGVATS
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHH
TGVERLLRDVEVMKIYEGTNDIQKLTIVKETARRLLGIKL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVLPFKSAEVFSVEVSEKHELFRKAVREFMERDVAPYVEKGEAQREVPKEILEKAKELGL
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCE
YGITVPEEYGGQGGDTLMSAIAQEEISRIWPSFATRVAAGALFTTPILLFGSEELKKKYV
EEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHCC
PPVARGEKVAALANTEPSAGSDVAGMQSTAKKINGKYILNGRKIFITNGGIADYYVVTAR
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCEEEEEECCCCEEEEEEEEC
TSPPDPKARWKGISMFVVEREWKGVKVVSRIDTLGLKASNTAELIFEDVEIPEENVVGEE
CCCCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHEECCCCCHHHCCCCC
GNGFKYAMATFDRTRVGVAAQALGVAQAALEKMVSYASQRIAFGEPIVMFELVQEKIAES
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LTEVNTARLLTYWAATLFDKGLENEAIVAASMAKYYSTEIAEKVVIRAITVHGGYGVATS
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHH
TGVERLLRDVEVMKIYEGTNDIQKLTIVKETARRLLGIKL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]