Click here to switch to the map view.

The map label for this gene is yqjP [H]

Identifier: 15920236

GI number: 15920236

Start: 77331

End: 78260

Strand: Direct

Name: yqjP [H]

Synonym: ST0057

Alternate gene names: 15920236

Gene position: 77331-78260 (Clockwise)

Preceding gene: 15920234

Following gene: 15920239

Centisome position: 2.87

GC content: 31.4

Gene sequence:

>930_bases
ATGAACGTTATGATATTGACTTTAAAATTACCTATGCAAGGTCCTCTAAATCATGTTAATGCATACTTGATAAGGGATGG
TAATGAATCACTACTAATTGACACTGGATTACCTACACAAGAAGCAATGTTAACACTTACCAATTATCTAAAAGAATACG
GTTACCCAAATTACGTAATAATCACACACTACCACCCAGATCACATAGGCTTAGTTAGACTATTTAAAGATAGTAATATA
TTTATTCATGAAAAAGAAATAGAGTATCTTAATTTTATATTAAGTAATGAGTATGAAAAAGAGATGAAAAACTACCTACT
CTCAAACGGATTCCCAGAGGATATTATAGATAGAATGTTTAGAAATAGGGACAGATTTTACGAAATAATCAAAGGTGTAA
ACTTCAACAAAGTTATTGATGGGGATACAATAAAGGTAGGAGGTAGTGAAATAAAAATCCTATGGACACCAGGGCACACA
ATGGGACACATATGCATCAAATATAATGAAATACTATTCTGCGGTGATCACATATTACCAAACATTACCCCCAACGTCTC
CCTACTCAGAGTCAATGACAACCCACTAAAATCATACTTAGATAGCCTTGATAAGATAGAGAAAATAAATGGTAAAATAT
ACCCAGCACACGGAGAACCAATCAACAATGTTAAAGAAAGAATTGAAGAAATCAAGGAACATCATAAGAATAGACTAGAA
GAAATATTAAAAATAATTGAAATGAAGGGAAAGGTTAACGGATTTGAGATAGCAATGAATATTTCATGGTACAAAAAATG
GGATGAACTCTCAAACTTTGATAAACAATTGGCCATAGGAGAAACACTAGCACATATAAAATACTTACTAGAGAAAAATG
CAATAAAACAAACAAACATAGGAAATAAAATTTATTACACCAAAAACTGA

Upstream 100 bases:

>100_bases
TAAATGATCTTTTCTTTAGAAGAAGTATAAATATTAAATTAGAGAAATGATAAATATATAGATATTGAGAGTAGATAAGT
TTAAATTTTGTCAGTTTTTA

Downstream 100 bases:

>100_bases
TACGGAAATTATACTTTCTGAGATTTTAAAGGACAAGGTCTCTTCTACACATTTCCGTGTAATTTGAAGGCTTGTTTCCT
TTTAAACTATGATCAAGTAT

Product: hypothetical protein

Products: Reduced glutathione; H+; D-Lactate [C]

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNVMILTLKLPMQGPLNHVNAYLIRDGNESLLIDTGLPTQEAMLTLTNYLKEYGYPNYVIITHYHPDHIGLVRLFKDSNI
FIHEKEIEYLNFILSNEYEKEMKNYLLSNGFPEDIIDRMFRNRDRFYEIIKGVNFNKVIDGDTIKVGGSEIKILWTPGHT
MGHICIKYNEILFCGDHILPNITPNVSLLRVNDNPLKSYLDSLDKIEKINGKIYPAHGEPINNVKERIEEIKEHHKNRLE
EILKIIEMKGKVNGFEIAMNISWYKKWDELSNFDKQLAIGETLAHIKYLLEKNAIKQTNIGNKIYYTKN

Sequences:

>Translated_309_residues
MNVMILTLKLPMQGPLNHVNAYLIRDGNESLLIDTGLPTQEAMLTLTNYLKEYGYPNYVIITHYHPDHIGLVRLFKDSNI
FIHEKEIEYLNFILSNEYEKEMKNYLLSNGFPEDIIDRMFRNRDRFYEIIKGVNFNKVIDGDTIKVGGSEIKILWTPGHT
MGHICIKYNEILFCGDHILPNITPNVSLLRVNDNPLKSYLDSLDKIEKINGKIYPAHGEPINNVKERIEEIKEHHKNRLE
EILKIIEMKGKVNGFEIAMNISWYKKWDELSNFDKQLAIGETLAHIKYLLEKNAIKQTNIGNKIYYTKN
>Mature_309_residues
MNVMILTLKLPMQGPLNHVNAYLIRDGNESLLIDTGLPTQEAMLTLTNYLKEYGYPNYVIITHYHPDHIGLVRLFKDSNI
FIHEKEIEYLNFILSNEYEKEMKNYLLSNGFPEDIIDRMFRNRDRFYEIIKGVNFNKVIDGDTIKVGGSEIKILWTPGHT
MGHICIKYNEILFCGDHILPNITPNVSLLRVNDNPLKSYLDSLDKIEKINGKIYPAHGEPINNVKERIEEIKEHHKNRLE
EILKIIEMKGKVNGFEIAMNISWYKKWDELSNFDKQLAIGETLAHIKYLLEKNAIKQTNIGNKIYYTKN

Specific function: Thiolesterase That Catalyzes The Hydrolysis Of S-D- Lactoyl-Glutathione To Form Glutathione And D-Lactic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI193205216, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537503, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: 3.1.2.6 [C]

Molecular weight: Translated: 36054; Mature: 36054

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVMILTLKLPMQGPLNHVNAYLIRDGNESLLIDTGLPTQEAMLTLTNYLKEYGYPNYVI
CCEEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEE
ITHYHPDHIGLVRLFKDSNIFIHEKEIEYLNFILSNEYEKEMKNYLLSNGFPEDIIDRMF
EEEECCCCEEEEEEEECCCEEEEECHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHH
RNRDRFYEIIKGVNFNKVIDGDTIKVGGSEIKILWTPGHTMGHICIKYNEILFCGDHILP
HCHHHHHHHHCCCCCCEEECCCEEEECCCEEEEEECCCCCEEEEEEEECCEEEECCCCCC
NITPNVSLLRVNDNPLKSYLDSLDKIEKINGKIYPAHGEPINNVKERIEEIKEHHKNRLE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
EILKIIEMKGKVNGFEIAMNISWYKKWDELSNFDKQLAIGETLAHIKYLLEKNAIKQTNI
HHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GNKIYYTKN
CCEEEEECC
>Mature Secondary Structure
MNVMILTLKLPMQGPLNHVNAYLIRDGNESLLIDTGLPTQEAMLTLTNYLKEYGYPNYVI
CCEEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEE
ITHYHPDHIGLVRLFKDSNIFIHEKEIEYLNFILSNEYEKEMKNYLLSNGFPEDIIDRMF
EEEECCCCEEEEEEEECCCEEEEECHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHH
RNRDRFYEIIKGVNFNKVIDGDTIKVGGSEIKILWTPGHTMGHICIKYNEILFCGDHILP
HCHHHHHHHHCCCCCCEEECCCEEEECCCEEEEEECCCCCEEEEEEEECCEEEECCCCCC
NITPNVSLLRVNDNPLKSYLDSLDKIEKINGKIYPAHGEPINNVKERIEEIKEHHKNRLE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
EILKIIEMKGKVNGFEIAMNISWYKKWDELSNFDKQLAIGETLAHIKYLLEKNAIKQTNI
HHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GNKIYYTKN
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; (R)-S-Lactoylglutathione [C]

Specific reaction: H2O + (R)-S-Lactoylglutathione --> Reduced glutathione + H+ + D-Lactate [C]

General reaction: Thioester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]