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The map label for this gene is ppiD [H]

Identifier: 15893195

GI number: 15893195

Start: 1173563

End: 1175137

Strand: Reverse

Name: ppiD [H]

Synonym: RC1272

Alternate gene names: 15893195

Gene position: 1175137-1173563 (Counterclockwise)

Preceding gene: 15893196

Following gene: 15893194

Centisome position: 92.62

GC content: 28.7

Gene sequence:

>1575_bases
ATGTTAGATAATATTAGAAAAACTACCGATAGTTTTATAATGCGGGTTTTATTCGCAATGATAGCTTTTGCTTTTGTCGG
CTTTGGTATTAAAGATGTATTAAATGGAAGAAGAAGTGGCGATATTGTTACTTTTTCTCATGTGAAAAATATCTCCCAGG
AAGATTTTTTGAGAGCAAAATCTTTAGAAATTAATGCTATAAGTAAGCAAACGGGAACAAGTTTAACGGATGAAGAAATA
GCACAGTTAAATATTGATAACCGAATCCTAAAAAGGCTTGTTTACGATAATGTCTTAGATTATTTAGTGAGTTATTATGA
CTTAGATCTAAGTGATGATACAGTTAAAATTTTAGTTAAAGAATCACCGGTTTTTAAAAATGAGCAAGGTGTTTTCAATA
TAAAAATTTTTAAAACTTATTTTAGAAATTCTTATATGGATGAAGAAAAATATTTATTAAACTTCAAAGAAAAAGCTCTA
AAAAATATTTTTGTTGGTACTTTTATAGAAAGTTTCTATGTTCCTAAAGCTATGACTGACAATATAGTAGATTATATGGC
TGAAAAAAGAGAAGTAGAATTAATACAAATAGATTTACAAAATAAACCGAAAGATTTACAAATCCCTACTCCTACCGGTC
AGCAATTAAAGGATTTTTACCAAGATAATAAAACCGCATTTGAGGTACCTGAGAAACGCAGCTTTTCTTATATTAAAGCT
AATATTAAGGATTTAAAAGTCTCAGTTACTCAAGATGAGTTGTTAGAATTTTATAATGAAAATAAAGATGAATTCGGTGA
TCAAAGTTTTGAAGCGGTACAAAAACAATTACATGATTTATTAAAGGCTCAAAAAATCGACATACTTAATATGGAGTTTG
CTAAAAAGCTGGAAGATGAGACGGCAGCCGGTTCTAGCTTAGTTGAAATTGCCGAAAAATATAAGCTACCGATACAAAAC
GTTAACTATATCAGTTATGCAGAGCTTATTGAAGATAAAATAATTGCTGAAAGTGCCGATAGTATTTTTGAGCTTTCGGA
AGGTGAATTATCTTATCCTATAGAAACAGAGGATAAAAGCTATCTTATATTGGTAGAATTAAAATCTATTCAGCCGGCAA
AAATACCTGAATTTGATGCTATTAAAGAGCAGGTAAATAAAGCTTGGATAAAGCGGAATATTGCAGATGTAAACTTAAAA
ATTATCAAGGATTTAGCAAAGGAATATAATTCAGATCAAAAGAACATAAAAGAGCTTAAAGCTACCGGAATAAAAATAAG
CAACAAAAGCTATATTAGATCCGAAATGGAAAATGATCTAACACTAACTCCTGAAATATTATTATCAATTTTTAATACTA
CAATAGGAAGTAATACGCCTGTATTTCAAGTAGGTGATGAAGTATATTTTGCACATATTAAATCTAGCAGTATCGATGAA
TTAACAGCTAAAAATATTCATGTCAATTCAGAAAAAAATATAATATATAATATTAAAAATTCTGTAATTGACGAGCTAAT
TAACTACACAATTATTCAGAATGATATGCAGGTAAAAGCTAATTTTAGTAAGTAG

Upstream 100 bases:

>100_bases
GAGCGAAGCAACGTGGCAATCTCGTCAAATATCCTGAGATTGCTTCGTCACTTACTTCGTAATTTCCTTGCAATGAAGAT
AAAAACTTAAATAAAAAATT

Downstream 100 bases:

>100_bases
CGAAATCCATCAGGTCATACCGTATCGTCATTGCGAGGAAATTACGAAGTAATTGAAGAAGCAATCTCAGGATATTTAAT
GAGATTGCCACGCAGCCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MLDNIRKTTDSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAKSLEINAISKQTGTSLTDEEI
AQLNIDNRILKRLVYDNVLDYLVSYYDLDLSDDTVKILVKESPVFKNEQGVFNIKIFKTYFRNSYMDEEKYLLNFKEKAL
KNIFVGTFIESFYVPKAMTDNIVDYMAEKREVELIQIDLQNKPKDLQIPTPTGQQLKDFYQDNKTAFEVPEKRSFSYIKA
NIKDLKVSVTQDELLEFYNENKDEFGDQSFEAVQKQLHDLLKAQKIDILNMEFAKKLEDETAAGSSLVEIAEKYKLPIQN
VNYISYAELIEDKIIAESADSIFELSEGELSYPIETEDKSYLILVELKSIQPAKIPEFDAIKEQVNKAWIKRNIADVNLK
IIKDLAKEYNSDQKNIKELKATGIKISNKSYIRSEMENDLTLTPEILLSIFNTTIGSNTPVFQVGDEVYFAHIKSSSIDE
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQVKANFSK

Sequences:

>Translated_524_residues
MLDNIRKTTDSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAKSLEINAISKQTGTSLTDEEI
AQLNIDNRILKRLVYDNVLDYLVSYYDLDLSDDTVKILVKESPVFKNEQGVFNIKIFKTYFRNSYMDEEKYLLNFKEKAL
KNIFVGTFIESFYVPKAMTDNIVDYMAEKREVELIQIDLQNKPKDLQIPTPTGQQLKDFYQDNKTAFEVPEKRSFSYIKA
NIKDLKVSVTQDELLEFYNENKDEFGDQSFEAVQKQLHDLLKAQKIDILNMEFAKKLEDETAAGSSLVEIAEKYKLPIQN
VNYISYAELIEDKIIAESADSIFELSEGELSYPIETEDKSYLILVELKSIQPAKIPEFDAIKEQVNKAWIKRNIADVNLK
IIKDLAKEYNSDQKNIKELKATGIKISNKSYIRSEMENDLTLTPEILLSIFNTTIGSNTPVFQVGDEVYFAHIKSSSIDE
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQVKANFSK
>Mature_524_residues
MLDNIRKTTDSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAKSLEINAISKQTGTSLTDEEI
AQLNIDNRILKRLVYDNVLDYLVSYYDLDLSDDTVKILVKESPVFKNEQGVFNIKIFKTYFRNSYMDEEKYLLNFKEKAL
KNIFVGTFIESFYVPKAMTDNIVDYMAEKREVELIQIDLQNKPKDLQIPTPTGQQLKDFYQDNKTAFEVPEKRSFSYIKA
NIKDLKVSVTQDELLEFYNENKDEFGDQSFEAVQKQLHDLLKAQKIDILNMEFAKKLEDETAAGSSLVEIAEKYKLPIQN
VNYISYAELIEDKIIAESADSIFELSEGELSYPIETEDKSYLILVELKSIQPAKIPEFDAIKEQVNKAWIKRNIADVNLK
IIKDLAKEYNSDQKNIKELKATGIKISNKSYIRSEMENDLTLTPEILLSIFNTTIGSNTPVFQVGDEVYFAHIKSSSIDE
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQVKANFSK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=487, Percent_Identity=20.9445585215606, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 60296; Mature: 60296

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNIRKTTDSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEHHHHCCCHHHHHHHH
SLEINAISKQTGTSLTDEEIAQLNIDNRILKRLVYDNVLDYLVSYYDLDLSDDTVKILVK
CCEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
ESPVFKNEQGVFNIKIFKTYFRNSYMDEEKYLLNFKEKALKNIFVGTFIESFYVPKAMTD
CCCCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
NIVDYMAEKREVELIQIDLQNKPKDLQIPTPTGQQLKDFYQDNKTAFEVPEKRSFSYIKA
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCHHHHHC
NIKDLKVSVTQDELLEFYNENKDEFGDQSFEAVQKQLHDLLKAQKIDILNMEFAKKLEDE
CHHHEEEEECHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
TAAGSSLVEIAEKYKLPIQNVNYISYAELIEDKIIAESADSIFELSEGELSYPIETEDKS
HCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCC
YLILVELKSIQPAKIPEFDAIKEQVNKAWIKRNIADVNLKIIKDLAKEYNSDQKNIKELK
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ATGIKISNKSYIRSEMENDLTLTPEILLSIFNTTIGSNTPVFQVGDEVYFAHIKSSSIDE
HCCEEECCHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCHHH
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQVKANFSK
HHHCCEEECCCCCEEEEHHHHHHHHHHHHEEEECCEEEEECCCC
>Mature Secondary Structure
MLDNIRKTTDSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEHHHHCCCHHHHHHHH
SLEINAISKQTGTSLTDEEIAQLNIDNRILKRLVYDNVLDYLVSYYDLDLSDDTVKILVK
CCEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
ESPVFKNEQGVFNIKIFKTYFRNSYMDEEKYLLNFKEKALKNIFVGTFIESFYVPKAMTD
CCCCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
NIVDYMAEKREVELIQIDLQNKPKDLQIPTPTGQQLKDFYQDNKTAFEVPEKRSFSYIKA
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCHHHHHC
NIKDLKVSVTQDELLEFYNENKDEFGDQSFEAVQKQLHDLLKAQKIDILNMEFAKKLEDE
CHHHEEEEECHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
TAAGSSLVEIAEKYKLPIQNVNYISYAELIEDKIIAESADSIFELSEGELSYPIETEDKS
HCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCC
YLILVELKSIQPAKIPEFDAIKEQVNKAWIKRNIADVNLKIIKDLAKEYNSDQKNIKELK
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ATGIKISNKSYIRSEMENDLTLTPEILLSIFNTTIGSNTPVFQVGDEVYFAHIKSSSIDE
HCCEEECCHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCHHH
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQVKANFSK
HHHCCEEECCCCCEEEEHHHHHHHHHHHHEEEECCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]