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The map label for this gene is corA [H]

Identifier: 15892866

GI number: 15892866

Start: 881706

End: 882665

Strand: Reverse

Name: corA [H]

Synonym: RC0943

Alternate gene names: 15892866

Gene position: 882665-881706 (Counterclockwise)

Preceding gene: 15892867

Following gene: 15892865

Centisome position: 69.57

GC content: 27.6

Gene sequence:

>960_bases
ATGATAACTACATATTTAAAGGAAAATAGTTCTATAGTAAAAAATGCAGAATATATTATTAATGAATCCACATTATGGAT
TGATTTATTCAATATAACAGATGAAGAAAAAGTAATAGTAAAAAATACATTAAATATAGAAATACCGACTTTAAAGGACA
TATCGCAAATTGAGATTTCTGAGAGGTTATATGTTGAAAATGAGGCGTTATATCTAACTATTACGGAACTCGTTAATAAA
GAGCAAGAATTTCCTGAAACACATTCTATAGTATTTATTTTGCATAAATGTTGTCTTATAACAGTTCGTTACGTAGAATT
AATACCCTTTAATGACTGTATAAATAAATTTGCTAAACAGCTTAATAACAAACATAATGCAGAAAATATTTTATTTATGT
TACTTCGTAATATGGTAACAAGATTATCGAATATTGTACAGTCGATTAGTATGGATATTGATGATTATGGACGTTTAATA
CTTGATAATAATATTAATGATTTGCGTATAGATCATACCAATGTATTAAAGAAAATAGGTCGAAAAGGTGATTTACTTTC
TAAAAGCCGTGAGTGTTTATTTTCTTTAACTATGGCTATTCAATATATTTTAAAATCTCCACAAATAACTCACAATAAAG
CATCTAAGGATCTATTAGATACATTGCTTCGAGACGTAGACTCAATAATTAATTTTTCACAATTTATATCTAGCGAGATT
GCAAGAACCCTAGACGCAGCACTCGGTATGATTGCAATTGAACAAAATAATATTATTAAAATTTTTTCGTTGGTTACTAT
ATTTTTTCTCCCACCCACTTTAATAGCTAGTATTTACGGCATGAATTTTACCGTAATGCCTGAGCTTAAATCACCGTATG
GTTATCCTATAGCCTTATTCTTAATGCTATTATCTACAATTATTACCTATAAATATTTTAAGAAACGGAAGTGGTTGTAA

Upstream 100 bases:

>100_bases
CAAGAAGTCTAATAATAGGAATCAGCTACGAGAATAAAAGCTTTCAGTTGCTTTAAAGAGTGAAGTTTGTTAATCTCTAT
AAAAACATATTTGAGATTAT

Downstream 100 bases:

>100_bases
GTTTTTATTGAGAATAGTTCGATAGAATTTTGCATAAAAATCAATGACCGTATTTTATAGTCAATTGATTTGGACTCACC
TACATCATTATTCGTTGCTT

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MITTYLKENSSIVKNAEYIINESTLWIDLFNITDEEKVIVKNTLNIEIPTLKDISQIEISERLYVENEALYLTITELVNK
EQEFPETHSIVFILHKCCLITVRYVELIPFNDCINKFAKQLNNKHNAENILFMLLRNMVTRLSNIVQSISMDIDDYGRLI
LDNNINDLRIDHTNVLKKIGRKGDLLSKSRECLFSLTMAIQYILKSPQITHNKASKDLLDTLLRDVDSIINFSQFISSEI
ARTLDAALGMIAIEQNNIIKIFSLVTIFFLPPTLIASIYGMNFTVMPELKSPYGYPIALFLMLLSTIITYKYFKKRKWL

Sequences:

>Translated_319_residues
MITTYLKENSSIVKNAEYIINESTLWIDLFNITDEEKVIVKNTLNIEIPTLKDISQIEISERLYVENEALYLTITELVNK
EQEFPETHSIVFILHKCCLITVRYVELIPFNDCINKFAKQLNNKHNAENILFMLLRNMVTRLSNIVQSISMDIDDYGRLI
LDNNINDLRIDHTNVLKKIGRKGDLLSKSRECLFSLTMAIQYILKSPQITHNKASKDLLDTLLRDVDSIINFSQFISSEI
ARTLDAALGMIAIEQNNIIKIFSLVTIFFLPPTLIASIYGMNFTVMPELKSPYGYPIALFLMLLSTIITYKYFKKRKWL
>Mature_319_residues
MITTYLKENSSIVKNAEYIINESTLWIDLFNITDEEKVIVKNTLNIEIPTLKDISQIEISERLYVENEALYLTITELVNK
EQEFPETHSIVFILHKCCLITVRYVELIPFNDCINKFAKQLNNKHNAENILFMLLRNMVTRLSNIVQSISMDIDDYGRLI
LDNNINDLRIDHTNVLKKIGRKGDLLSKSRECLFSLTMAIQYILKSPQITHNKASKDLLDTLLRDVDSIINFSQFISSEI
ARTLDAALGMIAIEQNNIIKIFSLVTIFFLPPTLIASIYGMNFTVMPELKSPYGYPIALFLMLLSTIITYKYFKKRKWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=323, Percent_Identity=28.7925696594427, Blast_Score=164, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36918; Mature: 36918

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTYLKENSSIVKNAEYIINESTLWIDLFNITDEEKVIVKNTLNIEIPTLKDISQIEIS
CCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCHHHHHHH
ERLYVENEALYLTITELVNKEQEFPETHSIVFILHKCCLITVRYVELIPFNDCINKFAKQ
HHEEEECCEEEEEHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LNNKHNAENILFMLLRNMVTRLSNIVQSISMDIDDYGRLILDNNINDLRIDHTNVLKKIG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCEEECHHHHHHHHC
RKGDLLSKSRECLFSLTMAIQYILKSPQITHNKASKDLLDTLLRDVDSIINFSQFISSEI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARTLDAALGMIAIEQNNIIKIFSLVTIFFLPPTLIASIYGMNFTVMPELKSPYGYPIALF
HHHHHHHHCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCCCCCCCCHHHHH
LMLLSTIITYKYFKKRKWL
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MITTYLKENSSIVKNAEYIINESTLWIDLFNITDEEKVIVKNTLNIEIPTLKDISQIEIS
CCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCHHHHHHH
ERLYVENEALYLTITELVNKEQEFPETHSIVFILHKCCLITVRYVELIPFNDCINKFAKQ
HHEEEECCEEEEEHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LNNKHNAENILFMLLRNMVTRLSNIVQSISMDIDDYGRLILDNNINDLRIDHTNVLKKIG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCEEECHHHHHHHHC
RKGDLLSKSRECLFSLTMAIQYILKSPQITHNKASKDLLDTLLRDVDSIINFSQFISSEI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARTLDAALGMIAIEQNNIIKIFSLVTIFFLPPTLIASIYGMNFTVMPELKSPYGYPIALF
HHHHHHHHCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCCCCCCCCHHHHH
LMLLSTIITYKYFKKRKWL
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]