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The map label for this gene is birA [H]

Identifier: 15892696

GI number: 15892696

Start: 732056

End: 732868

Strand: Reverse

Name: birA [H]

Synonym: RC0773

Alternate gene names: 15892696

Gene position: 732868-732056 (Counterclockwise)

Preceding gene: 15892697

Following gene: 15892695

Centisome position: 57.76

GC content: 32.6

Gene sequence:

>813_bases
ATGAATATCGGTAAATTTAAACTAATTGTTTTTGACAAGCTAGACAGTACAAACTCTGAGGCTATGAAAATGGCTCAGAA
TGCTAAAGTTGATTCAAACTATGCAGTACTTGCCAAATCCCAAACTAATGGACGCGGTAGAAGCGGCAAAAACTGGCAGT
CTAGGTCAGGTAACTTACATGTAAGTTTACTAATAAAGCCTGATAAAGAGCTAGAATTATTGCCGCAATTATCTTTTGTT
ACGGCACTTAGCGTTTATGATAGTATAACCTCTTTATGTCACTCCCATAGTGCTCTATGTCATTCCCGCTTTCGCGGGAA
TGACATAAGGAACGAAAATAACATTATACAACTAAAATGGCCCAATGATGTATTAATTAACAGTCGGAAAATTGCCGGTA
TACTTCTTGAATCTGTTAAAGTAGAAAATAATTATTACCTTATTATCGGTATCGGCATTAATATTACCTATCACCCTGAT
AATATCGACCAGCCTACTACTAGCTTAATAAGCGAAAATCTACCACCTATAGAACCGCAAGCTTTACTTGAGATATTAAT
AGAAAATTTTGAAGAATATTATCAAATTTGGCATAATAACGGTTTTCCTTTTATTAGAAAAAAATGGTTAGAACATGCTT
ATAAGTTATATGAAAATATTAGCGTTAAATATCAAAATGATATAGTAACCGGTCTTTTTAAAGATATCGATAATACCGGC
AGAATAATATTGCAACTACCGTCCAAAAAAATAATCTCTTTTTCCACTGCCGAACTTTTTTTTAGCAAAAATATTACTAA
ATTTAAATTGTAG

Upstream 100 bases:

>100_bases
TTTTTATGTCATTCATGCGAAAGCGGGAATGACATCGAGCGGGTTTTTCAAGCCATGCAACAAAGCTCGCCTTTCCTCGC
AATGACGGCTACTAAAAAAA

Downstream 100 bases:

>100_bases
ATTTAATTTTTGTTAACTTCTACTTAAGCTCCAATTTAACAAGGTAATAAATATATGCCCCAAGAGAATAACAACCCAAG
TTATCTGTCTCAAGCGTTTT

Product: biotin--protein ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MNIGKFKLIVFDKLDSTNSEAMKMAQNAKVDSNYAVLAKSQTNGRGRSGKNWQSRSGNLHVSLLIKPDKELELLPQLSFV
TALSVYDSITSLCHSHSALCHSRFRGNDIRNENNIIQLKWPNDVLINSRKIAGILLESVKVENNYYLIIGIGINITYHPD
NIDQPTTSLISENLPPIEPQALLEILIENFEEYYQIWHNNGFPFIRKKWLEHAYKLYENISVKYQNDIVTGLFKDIDNTG
RIILQLPSKKIISFSTAELFFSKNITKFKL

Sequences:

>Translated_270_residues
MNIGKFKLIVFDKLDSTNSEAMKMAQNAKVDSNYAVLAKSQTNGRGRSGKNWQSRSGNLHVSLLIKPDKELELLPQLSFV
TALSVYDSITSLCHSHSALCHSRFRGNDIRNENNIIQLKWPNDVLINSRKIAGILLESVKVENNYYLIIGIGINITYHPD
NIDQPTTSLISENLPPIEPQALLEILIENFEEYYQIWHNNGFPFIRKKWLEHAYKLYENISVKYQNDIVTGLFKDIDNTG
RIILQLPSKKIISFSTAELFFSKNITKFKL
>Mature_270_residues
MNIGKFKLIVFDKLDSTNSEAMKMAQNAKVDSNYAVLAKSQTNGRGRSGKNWQSRSGNLHVSLLIKPDKELELLPQLSFV
TALSVYDSITSLCHSHSALCHSRFRGNDIRNENNIIQLKWPNDVLINSRKIAGILLESVKVENNYYLIIGIGINITYHPD
NIDQPTTSLISENLPPIEPQALLEILIENFEEYYQIWHNNGFPFIRKKWLEHAYKLYENISVKYQNDIVTGLFKDIDNTG
RIILQLPSKKIISFSTAELFFSKNITKFKL

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 30918; Mature: 30918

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGKFKLIVFDKLDSTNSEAMKMAQNAKVDSNYAVLAKSQTNGRGRSGKNWQSRSGNLH
CCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEE
VSLLIKPDKELELLPQLSFVTALSVYDSITSLCHSHSALCHSRFRGNDIRNENNIIQLKW
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
PNDVLINSRKIAGILLESVKVENNYYLIIGIGINITYHPDNIDQPTTSLISENLPPIEPQ
CCCEEECCHHHHHHEEEEEEECCCEEEEEEEEEEEEECCCCCCCCHHHHHHCCCCCCCHH
ALLEILIENFEEYYQIWHNNGFPFIRKKWLEHAYKLYENISVKYQNDIVTGLFKDIDNTG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCCC
RIILQLPSKKIISFSTAELFFSKNITKFKL
EEEEEECCCCEEEEEHHHHHHHCCCEEECC
>Mature Secondary Structure
MNIGKFKLIVFDKLDSTNSEAMKMAQNAKVDSNYAVLAKSQTNGRGRSGKNWQSRSGNLH
CCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEE
VSLLIKPDKELELLPQLSFVTALSVYDSITSLCHSHSALCHSRFRGNDIRNENNIIQLKW
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
PNDVLINSRKIAGILLESVKVENNYYLIIGIGINITYHPDNIDQPTTSLISENLPPIEPQ
CCCEEECCHHHHHHEEEEEEECCCEEEEEEEEEEEEECCCCCCCCHHHHHHCCCCCCCHH
ALLEILIENFEEYYQIWHNNGFPFIRKKWLEHAYKLYENISVKYQNDIVTGLFKDIDNTG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCCC
RIILQLPSKKIISFSTAELFFSKNITKFKL
EEEEEECCCCEEEEEHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]