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The map label for this gene is hesB2 [C]

Identifier: 15892651

GI number: 15892651

Start: 701195

End: 701527

Strand: Reverse

Name: hesB2 [C]

Synonym: RC0728

Alternate gene names: 15892651

Gene position: 701527-701195 (Counterclockwise)

Preceding gene: 15892652

Following gene: 15892649

Centisome position: 55.29

GC content: 39.04

Gene sequence:

>333_bases
ATGAAAAATGTTATTTCATTAACCGATTCTGCTGCAAAGCAAATAAAATTGCTAATAGAAAAACGCGCCAAGCCTACCTT
TGGTATTAGGGTAGGGGTTAAGTCAGGCGGTTGTGCCGGTCAGACTTATTACGTGGAATATGCCGATAGTAAAAATCAAT
TCGATGAAGTAGTTGAAGAAAAGGGCGTACGGATACTAATCGACCCAAAGGCATTAATGTATATTCTAGGTTCTGAAATG
GACTATGTAGAGACTAAATTCAAATCCCAATTCACTTTCACCAATCCTAACGAAAAAGCTAGTTGCGGCTGCGGCAAATC
TTTTAGGGTGTAA

Upstream 100 bases:

>100_bases
ACCGGTCAAATTACATTGCTCACTACTTGCTGAAGATGCAATAAAAGCAGCTATAGCCGATTACAAACAGAAAAAAGAAA
GCAAAAAAGACTCTTAAAAT

Downstream 100 bases:

>100_bases
CACTTTAGAATCAATAAAGGTTTTAAAATATGTTTAACTGGGTTTATAATAAAATATTCTCTTATCCTTCACCTAATATT
GAAAGCTTACGAAAAGCACT

Product: hesB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MKNVISLTDSAAKQIKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEEKGVRILIDPKALMYILGSEM
DYVETKFKSQFTFTNPNEKASCGCGKSFRV

Sequences:

>Translated_110_residues
MKNVISLTDSAAKQIKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEEKGVRILIDPKALMYILGSEM
DYVETKFKSQFTFTNPNEKASCGCGKSFRV
>Mature_110_residues
MKNVISLTDSAAKQIKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEEKGVRILIDPKALMYILGSEM
DYVETKFKSQFTFTNPNEKASCGCGKSFRV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=46.2264150943396, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=42.4528301886792, Blast_Score=102, Evalue=5e-24,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=39.622641509434, Blast_Score=97, Evalue=3e-22,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=34.9056603773585, Blast_Score=76, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=109, Percent_Identity=44.0366972477064, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193209025, Length=109, Percent_Identity=44.0366972477064, Blast_Score=110, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=46.7289719626168, Blast_Score=106, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24642263, Length=108, Percent_Identity=45.3703703703704, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12257; Mature: 12257

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVISLTDSAAKQIKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEE
CCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHH
KGVRILIDPKALMYILGSEMDYVETKFKSQFTFTNPNEKASCGCGKSFRV
CCCEEEECCHHEEHHHCCCCCHHHHHHCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNVISLTDSAAKQIKLLIEKRAKPTFGIRVGVKSGGCAGQTYYVEYADSKNQFDEVVEE
CCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHH
KGVRILIDPKALMYILGSEMDYVETKFKSQFTFTNPNEKASCGCGKSFRV
CCCEEEECCHHEEHHHCCCCCHHHHHHCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]