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The map label for this gene is trpS

Identifier: 15892633

GI number: 15892633

Start: 682093

End: 683085

Strand: Reverse

Name: trpS

Synonym: RC0710

Alternate gene names: 15892633

Gene position: 683085-682093 (Counterclockwise)

Preceding gene: 15892637

Following gene: 15892620

Centisome position: 53.84

GC content: 33.64

Gene sequence:

>993_bases
ATGAAAAAAACTGTTCTTTCCGGTGTGCAAGCAACCGGTTCTTTACATCTCGGTAACTATCTTGGTGCAATTAAAAACTG
GGTTAAAATGCAGGAAGAATATAATTGTTTTTTCTTCTTAGCAGATTTGCATGCTATCACGGTTGATATTAAGCCATCAG
AACTTAACAATTCAATTATGGAGGTACTTGCTGTTTATTTAGCAGCAGGGCTTAACCCCGACAAAGTAACGATTTTTGCC
CAAAGTATGGTGAAAGAGCATACTGAACTTGCTTGGCTACTAAATTGCGTTACACCGCTTGGATGGTTAAAGCGCATGAC
GCAATTTAAAGATAAAGCAGGTAGTGATCAAGAAAAGGCTTGTCTTGGGTTATTTTCCTATCCGGTACTTATGGCAGCGG
ATATCTTAATATATAAAGCCGATATAGTGCCTGTAGGTGAGGATCAGAAGCAGCATTTAGAGCTAACAAGAGATATTGCA
GGGGTAATAAATAGAAAATTTAACAAAGAAATTCTAAAAGTTCCTGAGGTGTTAATTAGTGAAACAGGCACAAGAATCAT
GAGCTTACGGGATGGATTAAAGAAAATGAGTAAATCTGATATTTCGGATTTTTCCCGTATCAATTTAAAAGACGATAACG
ATCTTATTCATCAAAAAATAAAAAAAGCCAAAACCGATCATTTAAGTTTTGTTAGCTATGATCAAGAAACAAGACCGGAA
ATTAGTAATTTATTAGATATTTATAGCAGTTTATCCGAAGAAAGCTTGGAACAAATAATCGGTAATTATCAAAACCAAGG
TTTCGCAAAATTTAAAGAAGATTTGGCAGAAATTATTATTACAAATCTACAACCGATACGTGATAAATATTTAGAATTAA
TGAATGATAAAGAATATTTATTAAAAATACTGCACAAAGGAGCAGAAAAAGCAAGAATTAGAGCTTCTGAAACGGTTAAT
GAAGTGAAAGAACAATTCGGATTTGTAATTTAG

Upstream 100 bases:

>100_bases
AAAATTCTTAAACGCCACAGCATAATTATTAAGATAATTATATTAATTAAAATGGTATTTATAACATAATTTTACAATGA
GTAAAATAAAAAGGTATTAA

Downstream 100 bases:

>100_bases
ATTCATATATTGCAAGATTTCCCTTGAAATATATAAGATTATTTGGTATGAATCTTCTTGGGTAGGTGGCCGAGTGGTTT
AAGGCACTAGTCTTGAAAAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIMEVLAVYLAAGLNPDKVTIFA
QSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKACLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFNKEILKVPEVLISETGTRIMSLRDGLKKMSKSDISDFSRINLKDDNDLIHQKIKKAKTDHLSFVSYDQETRPE
ISNLLDIYSSLSEESLEQIIGNYQNQGFAKFKEDLAEIIITNLQPIRDKYLELMNDKEYLLKILHKGAEKARIRASETVN
EVKEQFGFVI

Sequences:

>Translated_330_residues
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIMEVLAVYLAAGLNPDKVTIFA
QSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKACLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFNKEILKVPEVLISETGTRIMSLRDGLKKMSKSDISDFSRINLKDDNDLIHQKIKKAKTDHLSFVSYDQETRPE
ISNLLDIYSSLSEESLEQIIGNYQNQGFAKFKEDLAEIIITNLQPIRDKYLELMNDKEYLLKILHKGAEKARIRASETVN
EVKEQFGFVI
>Mature_330_residues
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIMEVLAVYLAAGLNPDKVTIFA
QSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKACLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFNKEILKVPEVLISETGTRIMSLRDGLKKMSKSDISDFSRINLKDDNDLIHQKIKKAKTDHLSFVSYDQETRPE
ISNLLDIYSSLSEESLEQIIGNYQNQGFAKFKEDLAEIIITNLQPIRDKYLELMNDKEYLLKILHKGAEKARIRASETVN
EVKEQFGFVI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=41.6413373860182, Blast_Score=266, Evalue=1e-71,
Organism=Homo sapiens, GI41352700, Length=180, Percent_Identity=50, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1789786, Length=330, Percent_Identity=45.1515151515152, Blast_Score=295, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=36.969696969697, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=36.969696969697, Blast_Score=213, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=39.1304347826087, Blast_Score=232, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24666151, Length=327, Percent_Identity=39.4495412844037, Blast_Score=255, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYW_RICCN (Q92HR1)

Other databases:

- EMBL:   AE006914
- PIR:   F97788
- RefSeq:   NP_360347.1
- ProteinModelPortal:   Q92HR1
- SMR:   Q92HR1
- GeneID:   927621
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0710
- NMPDR:   fig|272944.1.peg.710
- OMA:   NKPGVSN
- ProtClustDB:   PRK00927
- BioCyc:   RCON272944:RC0710-MONOMER
- BRENDA:   6.1.1.2
- GO:   GO:0005737
- HAMAP:   MF_00140_B
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10055
- PRINTS:   PR01039
- TIGRFAMs:   TIGR00233

Pfam domain/function: PF00579 tRNA-synt_1b

EC number: =6.1.1.2

Molecular weight: Translated: 37506; Mature: 37506

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIM
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHEEEEEECCHHHHHHHHH
EVLAVYLAAGLNPDKVTIFAQSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIAGVINRKFNKEILKVPEVLIS
HHHHHHHHHHHHHHHHHEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGTRIMSLRDGLKKMSKSDISDFSRINLKDDNDLIHQKIKKAKTDHLSFVSYDQETRPE
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ISNLLDIYSSLSEESLEQIIGNYQNQGFAKFKEDLAEIIITNLQPIRDKYLELMNDKEYL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LKILHKGAEKARIRASETVNEVKEQFGFVI
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIM
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHEEEEEECCHHHHHHHHH
EVLAVYLAAGLNPDKVTIFAQSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIAGVINRKFNKEILKVPEVLIS
HHHHHHHHHHHHHHHHHEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGTRIMSLRDGLKKMSKSDISDFSRINLKDDNDLIHQKIKKAKTDHLSFVSYDQETRPE
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ISNLLDIYSSLSEESLEQIIGNYQNQGFAKFKEDLAEIIITNLQPIRDKYLELMNDKEYL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LKILHKGAEKARIRASETVNEVKEQFGFVI
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893