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The map label for this gene is mdtC [H]

Identifier: 15892492

GI number: 15892492

Start: 560007

End: 560225

Strand: Reverse

Name: mdtC [H]

Synonym: RC0569

Alternate gene names: 15892492

Gene position: 560225-560007 (Counterclockwise)

Preceding gene: 15892493

Following gene: 15892491

Centisome position: 44.16

GC content: 42.47

Gene sequence:

>219_bases
TTGCCTGGAGCTGACCCTACTACTATGGCATCTTCAGTTGCATTACCGCTTGAAAAGCAATGCTCGACGATATCAGATAT
TGACTCGATGAGTTCGGTTAATAGTAACGGTACTACTCAAATTACTTTGCAGTTTAATTTAGACCGAAATATAGATGCAG
CGGCACAAGACATACAAGCAACTACCGAACGACTTACCTACCCCGCCCTCATATTGTAA

Upstream 100 bases:

>100_bases
CATGGCAACTATTTTGCTGTTTGGAGCATTCGGCTATAGGATATGACCGGTAAGCGTTTTACCTGACATCAACTGCCCGA
CTATTCCGGTTTCAGTAAGC

Downstream 100 bases:

>100_bases
AGTAAATCCTGCCGACGCACCTATATTTTATTTATCTTTAACCTCTGAGACTCTTCCCCTTATATACCGTGGACTATTAC
GCTGAAACAATTATGGCTGA

Product: RND efflux transporter

Products: NA

Alternate protein names: Multidrug transporter MdtC [H]

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MPGADPTTMASSVALPLEKQCSTISDIDSMSSVNSNGTTQITLQFNLDRNIDAAAQDIQATTERLTYPALIL

Sequences:

>Translated_72_residues
MPGADPTTMASSVALPLEKQCSTISDIDSMSSVNSNGTTQITLQFNLDRNIDAAAQDIQATTERLTYPALIL
>Mature_71_residues
PGADPTTMASSVALPLEKQCSTISDIDSMSSVNSNGTTQITLQFNLDRNIDAAAQDIQATTERLTYPALIL

Specific function: Could Be A Drug Efflux Pump (By Similarity). [C]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788391, Length=60, Percent_Identity=53.3333333333333, Blast_Score=70, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 7659; Mature: 7527

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGADPTTMASSVALPLEKQCSTISDIDSMSSVNSNGTTQITLQFNLDRNIDAAAQDIQA
CCCCCCCCCCHHCCCCCHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHH
TTERLTYPALIL
HHHHCCCCEECC
>Mature Secondary Structure 
PGADPTTMASSVALPLEKQCSTISDIDSMSSVNSNGTTQITLQFNLDRNIDAAAQDIQA
CCCCCCCCCHHCCCCCHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHH
TTERLTYPALIL
HHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA