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The map label for this gene is aprE [H]

Identifier: 15892351

GI number: 15892351

Start: 424292

End: 425827

Strand: Reverse

Name: aprE [H]

Synonym: RC0428

Alternate gene names: 15892351

Gene position: 425827-424292 (Counterclockwise)

Preceding gene: 15892352

Following gene: 15892350

Centisome position: 33.56

GC content: 33.79

Gene sequence:

>1536_bases
ATGCAGGACTTAAAACACAATAAACCTCAAATTACTCCGGAACAATTAAAACAATTATTGTCCTTAAGAGAAGATGCGTT
AAATCTTAAAGGTCAAAGTTCTAAACGTAAAGCTTTAATAAATACTACATTAAAGAAAACCTCTCATGCTATAGAATTCT
TATTAGTAAAACTTGATAGGTTTGTTAATTTTATTACCAAGAAAACCGATAAAGATCGTAATAACGTAGCCCAAGCTGCA
AGATCACCTATACTTTTCGGTATTTATGTTATGATCTTTTTAGTATTAATAGGTGGATTATGGTCGGCTCTTGCTCCACT
TGATAGTGGTGCTGTAGCTGTCGGTATCGTAATGCCAAGCACAAATAAAAAAACGATTCAACATCATGAAGGCGGAATAA
TCAATGCTATTTATGTGAAGCAAGGTGATAAAGTCAAAGAAGGCGATAAATTAATAGAGCTTGAAGAAACTAGAATAAAA
AGCGAACATGAAAATATTCTTGGTCAGTACCGTAATTTTTTAGCAACTGAAAATCGTTTAATTGCCGAACGTGATAATTT
AGAACAAATCGAATTCTCTGATTTTCTAATGCAGGATATCAATTTACCGGAAGTAGCTAAAATAATTCATACGCAGGAAA
ATTTATTTAGATCTAGAAAAGAAGTATATAACTCAGAGAAAGATGCATTACATCAAAATATTGCTCAACTTGAGAAAAAA
ATTGAAGGTTTAGAAGCAAAAAAAGTTGCCGCCTCCAAAACTGCTGAAGTTTATCAAGACCGTTTAAAAGCTTTAAGAAC
GTTAAAAGAAAAAGGCTTTGTACAAAAAGCAGCCTTATTAGACCAAGAGGCAAAAGTTGCCGCTTCAAAAAGCGATGTTG
CAACAACTGAAGCCGAAATAGCAGGAATACGCCATGCTATTACCGAAACTCAAATTAAAATTATAAATCAACAAAATAAA
TACACTGAACGGACTTTAACAGAGCTTCGTGAAGCTCAAGTACAAACCGCATCTCTTAAAGAAAAATATAATGCCCTGAC
GGATTCGCTTAATCGTGTGATAATCAGAGCACCTGTTGACGGTATAGTTAATAGTTTAAAATATCATACAATAGGCGGTG
TTATAAGTCACGGACAACCTATTATGGAAATTTCGCCAACTAATGACCCATTAATAATAGAAGCAAAGGTATCTCAAAAA
AACATTGACTCAGTACATGAGGGATTAGTTGCAAAAATACGTTTCAGTGCATTTAAATCAAGAACAACTCCAACATTTAC
CGGTAAAGTAGTAAGCATATCTCCCGATATCGTACAAGATGAAAGACAGTATCCGGGACAACAGCAAGATAATTATTATG
TTGCAAGAGTTGAAATCGATATGGATGAATTTAACAAAGTTGCTAAAGTTAAAAATCTTGAATTACACCCCGGTATGCAA
GCTGAGGTACAAATCGTAACAGGTACTAGAACACTACTTAGATATTTACTTGATCCCGTTACTGATACTGCATTTAAAGC
TTTCAGAGAAAAATAG

Upstream 100 bases:

>100_bases
ATGAATTCTATCGAGATTGCTTCGTCAATTACTACATCATGTCCTCGCAATGACGCAAAATACAAACAATACTGACTAAA
TATAATAATGATTAAATATT

Downstream 100 bases:

>100_bases
ATAATTTGAAAATTTTAAGTTAGATAACTTTACGAAACCTAAATATTTACAATATTTATTAAAAATTCTTAATCCTTTAT
TGACTTTGAATCAAAAGCAG

Product: alkaline protease secretion protein AprE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MQDLKHNKPQITPEQLKQLLSLREDALNLKGQSSKRKALINTTLKKTSHAIEFLLVKLDRFVNFITKKTDKDRNNVAQAA
RSPILFGIYVMIFLVLIGGLWSALAPLDSGAVAVGIVMPSTNKKTIQHHEGGIINAIYVKQGDKVKEGDKLIELEETRIK
SEHENILGQYRNFLATENRLIAERDNLEQIEFSDFLMQDINLPEVAKIIHTQENLFRSRKEVYNSEKDALHQNIAQLEKK
IEGLEAKKVAASKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEIAGIRHAITETQIKIINQQNK
YTERTLTELREAQVQTASLKEKYNALTDSLNRVIIRAPVDGIVNSLKYHTIGGVISHGQPIMEISPTNDPLIIEAKVSQK
NIDSVHEGLVAKIRFSAFKSRTTPTFTGKVVSISPDIVQDERQYPGQQQDNYYVARVEIDMDEFNKVAKVKNLELHPGMQ
AEVQIVTGTRTLLRYLLDPVTDTAFKAFREK

Sequences:

>Translated_511_residues
MQDLKHNKPQITPEQLKQLLSLREDALNLKGQSSKRKALINTTLKKTSHAIEFLLVKLDRFVNFITKKTDKDRNNVAQAA
RSPILFGIYVMIFLVLIGGLWSALAPLDSGAVAVGIVMPSTNKKTIQHHEGGIINAIYVKQGDKVKEGDKLIELEETRIK
SEHENILGQYRNFLATENRLIAERDNLEQIEFSDFLMQDINLPEVAKIIHTQENLFRSRKEVYNSEKDALHQNIAQLEKK
IEGLEAKKVAASKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEIAGIRHAITETQIKIINQQNK
YTERTLTELREAQVQTASLKEKYNALTDSLNRVIIRAPVDGIVNSLKYHTIGGVISHGQPIMEISPTNDPLIIEAKVSQK
NIDSVHEGLVAKIRFSAFKSRTTPTFTGKVVSISPDIVQDERQYPGQQQDNYYVARVEIDMDEFNKVAKVKNLELHPGMQ
AEVQIVTGTRTLLRYLLDPVTDTAFKAFREK
>Mature_511_residues
MQDLKHNKPQITPEQLKQLLSLREDALNLKGQSSKRKALINTTLKKTSHAIEFLLVKLDRFVNFITKKTDKDRNNVAQAA
RSPILFGIYVMIFLVLIGGLWSALAPLDSGAVAVGIVMPSTNKKTIQHHEGGIINAIYVKQGDKVKEGDKLIELEETRIK
SEHENILGQYRNFLATENRLIAERDNLEQIEFSDFLMQDINLPEVAKIIHTQENLFRSRKEVYNSEKDALHQNIAQLEKK
IEGLEAKKVAASKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEIAGIRHAITETQIKIINQQNK
YTERTLTELREAQVQTASLKEKYNALTDSLNRVIIRAPVDGIVNSLKYHTIGGVISHGQPIMEISPTNDPLIIEAKVSQK
NIDSVHEGLVAKIRFSAFKSRTTPTFTGKVVSISPDIVQDERQYPGQQQDNYYVARVEIDMDEFNKVAKVKNLELHPGMQ
AEVQIVTGTRTLLRYLLDPVTDTAFKAFREK

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 57583; Mature: 57583

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLKHNKPQITPEQLKQLLSLREDALNLKGQSSKRKALINTTLKKTSHAIEFLLVKLDR
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVNFITKKTDKDRNNVAQAARSPILFGIYVMIFLVLIGGLWSALAPLDSGAVAVGIVMPS
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
TNKKTIQHHEGGIINAIYVKQGDKVKEGDKLIELEETRIKSEHENILGQYRNFLATENRL
CCCCHHHHCCCCEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
IAERDNLEQIEFSDFLMQDINLPEVAKIIHTQENLFRSRKEVYNSEKDALHQNIAQLEKK
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IEGLEAKKVAASKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHCCCCHHHHHHHHH
AGIRHAITETQIKIINQQNKYTERTLTELREAQVQTASLKEKYNALTDSLNRVIIRAPVD
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHH
GIVNSLKYHTIGGVISHGQPIMEISPTNDPLIIEAKVSQKNIDSVHEGLVAKIRFSAFKS
HHHHHHHHHHHCCHHHCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
RTTPTFTGKVVSISPDIVQDERQYPGQQQDNYYVARVEIDMDEFNKVAKVKNLELHPGMQ
CCCCCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCC
AEVQIVTGTRTLLRYLLDPVTDTAFKAFREK
EEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDLKHNKPQITPEQLKQLLSLREDALNLKGQSSKRKALINTTLKKTSHAIEFLLVKLDR
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVNFITKKTDKDRNNVAQAARSPILFGIYVMIFLVLIGGLWSALAPLDSGAVAVGIVMPS
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
TNKKTIQHHEGGIINAIYVKQGDKVKEGDKLIELEETRIKSEHENILGQYRNFLATENRL
CCCCHHHHCCCCEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
IAERDNLEQIEFSDFLMQDINLPEVAKIIHTQENLFRSRKEVYNSEKDALHQNIAQLEKK
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IEGLEAKKVAASKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHCCCCHHHHHHHHH
AGIRHAITETQIKIINQQNKYTERTLTELREAQVQTASLKEKYNALTDSLNRVIIRAPVD
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHH
GIVNSLKYHTIGGVISHGQPIMEISPTNDPLIIEAKVSQKNIDSVHEGLVAKIRFSAFKS
HHHHHHHHHHHCCHHHCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
RTTPTFTGKVVSISPDIVQDERQYPGQQQDNYYVARVEIDMDEFNKVAKVKNLELHPGMQ
CCCCCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCC
AEVQIVTGTRTLLRYLLDPVTDTAFKAFREK
EEEEEEECHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]