BacMap

Definition	Rickettsia conorii str. Malish 7, complete genome.
Accession	NC_003103
Length	1,268,755

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The map label for this gene is dnaJ [H]

Identifier: 15892155

GI number: 15892155

Start: 241505

End: 242626

Strand: Reverse

Name: dnaJ [H]

Synonym: RC0232

Alternate gene names: 15892155

Gene position: 242626-241505 (Counterclockwise)

Preceding gene: 15892156

Following gene: 15892154

Centisome position: 19.12

GC content: 38.41

Gene sequence:

>1122_bases
ATGTCACAAAATTATTACCAAATACTAGGGGTTAGTAAAACAGCTAGCCAAGCTGACCTTAAAAAAGCCTACCTCAAGCT
AGCCAAGCAATATCACCCTGATACTACTGATGCTAAAGATGCTGAAAAGAAATTTAAAGAAATCAATGCCGCTTATGATG
TTCTAAAAGATGAGCAAAAAAGAGCTGCTTATGACCGTTTGGGACACGATGCTTTTCAAAATCAACAATCACGAGGGGGA
GGAGGAAATCATGGCGGTTTTCACCCTGATATTAACGACATATTCGGTGACTTCTTTAGCGACTTTATGGGAGGCAGCAG
AAGATCATCACGCCCAACTTCAGCTAAAGTTAGAGGCTCAGATTTAAAATATAATCTGACAATTAACCTAGAGGAAGCAT
TTCACGGTATAGAAAAAAATATTAGCTTTTCTAGCGCAGTAAAATGCGATACTTGTCACGGTAGCGGTTCTGAAAAAGGT
GAAACCGTAACTACTTGCGATGCTTGCAGCGGTGTTGGAGCGACTAGAATGCAGCAAGGATTCTTTACGATCGAACAAGC
TTGTCATAAATGCCAAGGTAACGGACACATTATAAAAAATCCTTGCAAGAAATGTCATGGCATGGGACGTTACCATAAAC
AACGAAATTTATCGGTAAACATTCCTGCCGGTGTTGAAAACGGTACTAGAATAAGACATACCGGAGAAGGGGAAGCAGGC
ATTAGAGGCGGTAATAGCGGTGATTTATATGTTGATATAACAATAAAACCACATGATATTTATAAAGTAGACGGAGCAAA
TCTACATTGTAAACTACCTATTAGTTTTGTGAATGCTGCTCTTGGAGGAGAGATAGAAGTACCGGTAATTGAAGGCGGAA
AAGTAAACTTAACAATTCCTGCAGGCACACAAAACGGTGATCAATTAAGGCTACGCAGCAAAGGTATGTCTAAAATGAGA
TCAACTATTAGGGGTGATATGCTTACGCATATTCATGTCGAAGTACCTAAAAATTTATCTAAAAGACAACGTGAATTACT
AGAAGAATTCAAAAAAGAATCCATAAATGAGAAAGAAAATGACGGCAGCTTTTTTAATAAAATGAAAAGTCTGTGGTCGT
AA

Upstream 100 bases:

>100_bases
GCGACGTGGCAATCTCGTTAAATATCCTGAGATTGCTTTGTCAAATTACTATGTAATTTTCCTCGTAATGACGTTACAAT
CTCATTTTATAAATTAACTT

Downstream 100 bases:

>100_bases
ATTTGATTTACCTTTCCTATAGCAATGAAACCTCCAATATTATAAAATATTATTTGCATAATATTACCGGAGGTTTTTAT
GCCTTATAAGAATAATAACG

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MSQNYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRLGHDAFQNQQSRGG
GGNHGGFHPDINDIFGDFFSDFMGGSRRSSRPTSAKVRGSDLKYNLTINLEEAFHGIEKNISFSSAVKCDTCHGSGSEKG
ETVTTCDACSGVGATRMQQGFFTIEQACHKCQGNGHIIKNPCKKCHGMGRYHKQRNLSVNIPAGVENGTRIRHTGEGEAG
IRGGNSGDLYVDITIKPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGGKVNLTIPAGTQNGDQLRLRSKGMSKMR
STIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESINEKENDGSFFNKMKSLWS

Sequences:

>Translated_373_residues
MSQNYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRLGHDAFQNQQSRGG
GGNHGGFHPDINDIFGDFFSDFMGGSRRSSRPTSAKVRGSDLKYNLTINLEEAFHGIEKNISFSSAVKCDTCHGSGSEKG
ETVTTCDACSGVGATRMQQGFFTIEQACHKCQGNGHIIKNPCKKCHGMGRYHKQRNLSVNIPAGVENGTRIRHTGEGEAG
IRGGNSGDLYVDITIKPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGGKVNLTIPAGTQNGDQLRLRSKGMSKMR
STIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESINEKENDGSFFNKMKSLWS
>Mature_372_residues
SQNYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRLGHDAFQNQQSRGGG
GNHGGFHPDINDIFGDFFSDFMGGSRRSSRPTSAKVRGSDLKYNLTINLEEAFHGIEKNISFSSAVKCDTCHGSGSEKGE
TVTTCDACSGVGATRMQQGFFTIEQACHKCQGNGHIIKNPCKKCHGMGRYHKQRNLSVNIPAGVENGTRIRHTGEGEAGI
RGGNSGDLYVDITIKPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGGKVNLTIPAGTQNGDQLRLRSKGMSKMRS
TIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESINEKENDGSFFNKMKSLWS

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=359, Percent_Identity=33.4261838440111, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI205360840, Length=359, Percent_Identity=33.4261838440111, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI4504511, Length=370, Percent_Identity=31.6216216216216, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI5031741, Length=344, Percent_Identity=32.2674418604651, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI194328760, Length=349, Percent_Identity=29.2263610315186, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI194328758, Length=349, Percent_Identity=29.2263610315186, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI7706495, Length=364, Percent_Identity=29.3956043956044, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI5453690, Length=367, Percent_Identity=25.6130790190736, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI6631085, Length=374, Percent_Identity=26.7379679144385, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI194328762, Length=312, Percent_Identity=26.2820512820513, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI9558755, Length=101, Percent_Identity=47.5247524752475, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI201862518, Length=122, Percent_Identity=41.8032786885246, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI201862587, Length=122, Percent_Identity=41.8032786885246, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI56549115, Length=122, Percent_Identity=41.8032786885246, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI23503241, Length=109, Percent_Identity=43.1192660550459, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI194306642, Length=111, Percent_Identity=45.945945945946, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI194306640, Length=111, Percent_Identity=45.945945945946, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI56687498, Length=69, Percent_Identity=55.0724637681159, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI72534740, Length=104, Percent_Identity=44.2307692307692, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI27151736, Length=105, Percent_Identity=43.8095238095238, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI88501736, Length=105, Percent_Identity=43.8095238095238, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI39204547, Length=372, Percent_Identity=21.7741935483871, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21553335, Length=107, Percent_Identity=39.2523364485981, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI17388799, Length=65, Percent_Identity=49.2307692307692, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4885495, Length=65, Percent_Identity=49.2307692307692, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI47777312, Length=129, Percent_Identity=35.6589147286822, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI22749377, Length=104, Percent_Identity=41.3461538461538, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21361912, Length=62, Percent_Identity=48.3870967741936, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI68077168, Length=96, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI68077166, Length=96, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI24308127, Length=75, Percent_Identity=44, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786197, Length=377, Percent_Identity=48.0106100795756, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1787235, Length=351, Percent_Identity=31.3390313390313, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17553096, Length=350, Percent_Identity=36, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17553098, Length=367, Percent_Identity=35.149863760218, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17563890, Length=365, Percent_Identity=31.2328767123288, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507263, Length=368, Percent_Identity=29.3478260869565, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI212645553, Length=364, Percent_Identity=30.4945054945055, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534355, Length=106, Percent_Identity=44.3396226415094, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554900, Length=173, Percent_Identity=32.3699421965318, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86563276, Length=102, Percent_Identity=42.156862745098, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532378, Length=106, Percent_Identity=39.622641509434, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538236, Length=87, Percent_Identity=42.5287356321839, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554644, Length=99, Percent_Identity=41.4141414141414, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=359, Percent_Identity=32.5905292479109, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323870, Length=363, Percent_Identity=33.6088154269972, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6321094, Length=396, Percent_Identity=29.2929292929293, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323119, Length=393, Percent_Identity=27.2264631043257, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324252, Length=417, Percent_Identity=27.5779376498801, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323813, Length=113, Percent_Identity=39.8230088495575, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324103, Length=67, Percent_Identity=52.2388059701493, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324321, Length=66, Percent_Identity=50, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322388, Length=93, Percent_Identity=37.6344086021505, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45552813, Length=372, Percent_Identity=31.4516129032258, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI45552811, Length=372, Percent_Identity=31.4516129032258, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45549272, Length=372, Percent_Identity=31.4516129032258, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24646562, Length=350, Percent_Identity=31.7142857142857, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646560, Length=350, Percent_Identity=31.7142857142857, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646558, Length=350, Percent_Identity=31.7142857142857, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646556, Length=350, Percent_Identity=31.7142857142857, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21357547, Length=350, Percent_Identity=31.7142857142857, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI85726398, Length=367, Percent_Identity=27.7929155313352, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI20129487, Length=359, Percent_Identity=29.8050139275766, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24584014, Length=359, Percent_Identity=29.8050139275766, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28574949, Length=350, Percent_Identity=25.7142857142857, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19920464, Length=355, Percent_Identity=28.7323943661972, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24658562, Length=364, Percent_Identity=26.0989010989011, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658555, Length=364, Percent_Identity=26.0989010989011, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18858081, Length=348, Percent_Identity=26.1494252873563, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24654066, Length=117, Percent_Identity=40.1709401709402, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654070, Length=117, Percent_Identity=40.1709401709402, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654068, Length=117, Percent_Identity=40.1709401709402, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654072, Length=117, Percent_Identity=40.1709401709402, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668492, Length=73, Percent_Identity=43.8356164383562, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668523, Length=64, Percent_Identity=53.125, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17737735, Length=64, Percent_Identity=53.125, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574723, Length=64, Percent_Identity=53.125, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=46.875, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355911, Length=99, Percent_Identity=43.4343434343434, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 41132; Mature: 41001

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2 ; PS00637 DNAJ_CXXCXGXG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQK
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RAAYDRLGHDAFQNQQSRGGGGNHGGFHPDINDIFGDFFSDFMGGSRRSSRPTSAKVRGS
HHHHHHHCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
DLKYNLTINLEEAFHGIEKNISFSSAVKCDTCHGSGSEKGETVTTCDACSGVGATRMQQG
CEEEEEEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEHHHHCCCCHHHHHHH
FFTIEQACHKCQGNGHIIKNPCKKCHGMGRYHKQRNLSVNIPAGVENGTRIRHTGEGEAG
HHHHHHHHHHHCCCCCEECCHHHHHHCCCHHHHHCCCEEECCCCCCCCCEEEECCCCCCC
IRGGNSGDLYVDITIKPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGGKVNLTIP
CCCCCCCCEEEEEEECCCEEEEECCCCEEEECCHHHHHHHCCCCEEEEEECCCEEEEEEE
AGTQNGDQLRLRSKGMSKMRSTIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESINEKEN
CCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
DGSFFNKMKSLWS
CHHHHHHHHHHCC
>Mature Secondary Structure 
SQNYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RAAYDRLGHDAFQNQQSRGGGGNHGGFHPDINDIFGDFFSDFMGGSRRSSRPTSAKVRGS
HHHHHHHCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
DLKYNLTINLEEAFHGIEKNISFSSAVKCDTCHGSGSEKGETVTTCDACSGVGATRMQQG
CEEEEEEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEHHHHCCCCHHHHHHH
FFTIEQACHKCQGNGHIIKNPCKKCHGMGRYHKQRNLSVNIPAGVENGTRIRHTGEGEAG
HHHHHHHHHHHCCCCCEECCHHHHHHCCCHHHHHCCCEEECCCCCCCCCEEEECCCCCCC
IRGGNSGDLYVDITIKPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGGKVNLTIP
CCCCCCCCEEEEEEECCCEEEEECCCCEEEECCHHHHHHHCCCCEEEEEECCCEEEEEEE
AGTQNGDQLRLRSKGMSKMRSTIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESINEKEN
CCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
DGSFFNKMKSLWS
CHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA