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The map label for this gene is gcp [H]

Identifier: 15891984

GI number: 15891984

Start: 53323

End: 54357

Strand: Reverse

Name: gcp [H]

Synonym: RC0061

Alternate gene names: 15891984

Gene position: 54357-53323 (Counterclockwise)

Preceding gene: 15891985

Following gene: 15891983

Centisome position: 4.28

GC content: 34.2

Gene sequence:

>1035_bases
ATGATAAAAATTTTAGGTATAGAATCAAGCTGTGATGATACAGCTGTTTCTATAATCACCGAAAATCGAGAAATCTTATC
TAATATAATCATTTCACAAAATACAGAACATGCAGTTTTTGGAGGGGTAGTACCTGAAATTGCTGCACGTTCTCACTTAT
CGCATCTAGATAAAGCATTAAAAAATGTTTTAAAAGAAAGCAACACTAAATTAACGGACATTAGTACAATTGCTGCAACT
TCCGGTCCAGGTTTAATCGGCGGTGTTATAGTTGGCTCAATGTTTGCAAGATCACTAAGCAGTGCTTTAAAAAAACCCTT
TATTGCAATTAATCATTTAGAAGGTCATGCTTTAACCGCAAGACTAACCGATAATATTCCTTATCCTTATTTACTCTTGT
TAGCTTCAGGCGGACATTGCCAATTTGTAGCAGTTTTAGGTCTCGGAAAATATAAAATACTAGGATCTACTATAGATGAT
GCCGTAGGCGAAGCCTTTGACAAGGTAGCCAAAATGCTAAACTTAGCTTTTCCCGGAGGACCTGAAATTGAGAAAAGAGC
AAAACTTGGCGATCCTCATAAATATAAATTTCCAAAACCTATAATTAACAGCGGTAATTGCAATATGTCCTTTTCAGGAC
TTAAAACTGCCGTGCGTACTTTAATAATGACTTTAAAGGAAATTAATGACACTGTAATCAATGATATAGCGGCAAGTTTT
CAATTTACTATAGGAGAAATTCTAAGTAGTAAGGTACAAGATGCTATTAGAGCATATGAACAAATAACAAATAATTTTGA
TAAGAAGAATATAGTTATTGCCGGCGGTGTCGCTGCTAATAAATATTTACAAAAAATATTAAGTAGCTGTGCTAAAACAT
ATGGTTATCGGCTTATTTATCCACCTATCCACTTATGCACCGATAATGCTGCAATGATTGCATATGCAGGACTTGAGCGT
TACAATAATAAGTTATTTACTCCTTTGAATTTCTGTCCAAAAGCTAGGTGGAGTTTAGAGGATATTAGTAATTAA

Upstream 100 bases:

>100_bases
TAAAGATAGATATCGTGATTACAAGCGGGTGTTGGTGTTGTCACAATGACGCAAACTATCATTTTTTACTTAACAACGCC
TCTAATTAGTTTCAATTTGA

Downstream 100 bases:

>100_bases
AATTTATTTACTGATATCCTCTAAGAAGAAATATAATTTTTTAATATTGACACTTCTTAATTTAGTAGTATGATATGTAA
TTACCATAAAACATGGCAAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKALKNVLKESNTKLTDISTIAAT
SGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDD
AVGEAFDKVAKMLNLAFPGGPEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMTLKEINDTVINDIAASF
QFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIYPPIHLCTDNAAMIAYAGLER
YNNKLFTPLNFCPKARWSLEDISN

Sequences:

>Translated_344_residues
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKALKNVLKESNTKLTDISTIAAT
SGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDD
AVGEAFDKVAKMLNLAFPGGPEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMTLKEINDTVINDIAASF
QFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIYPPIHLCTDNAAMIAYAGLER
YNNKLFTPLNFCPKARWSLEDISN
>Mature_344_residues
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKALKNVLKESNTKLTDISTIAAT
SGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDD
AVGEAFDKVAKMLNLAFPGGPEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMTLKEINDTVINDIAASF
QFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIYPPIHLCTDNAAMIAYAGLER
YNNKLFTPLNFCPKARWSLEDISN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=36.6863905325444, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI8923380, Length=332, Percent_Identity=29.2168674698795, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=40.6432748538012, Blast_Score=264, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=33.1325301204819, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=324, Percent_Identity=32.7160493827161, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=368, Percent_Identity=31.5217391304348, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322891, Length=344, Percent_Identity=27.0348837209302, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=36.3905325443787, Blast_Score=220, Evalue=9e-58,
Organism=Drosophila melanogaster, GI21357207, Length=342, Percent_Identity=29.8245614035088, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37303; Mature: 37303

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKAL
CEEEEECCCCCCCHHHEEEECCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
KNVLKESNTKLTDISTIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTA
HHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEE
RLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGEAFDKVAKMLNLAFPGG
EECCCCCCCEEEEEECCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCC
PEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMTLKEINDTVINDIAASF
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEEC
PPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWSLEDISN
CCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSHLDKAL
CEEEEECCCCCCCHHHEEEECCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
KNVLKESNTKLTDISTIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTA
HHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEE
RLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGEAFDKVAKMLNLAFPGG
EECCCCCCCEEEEEECCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCC
PEIEKRAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMTLKEINDTVINDIAASF
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFTIGEILSSKVQDAIRAYEQITNNFDKKNIVIAGGVAANKYLQKILSSCAKTYGYRLIY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEEC
PPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWSLEDISN
CCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA