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The map label for this gene is folKP [H]

Identifier: 15891961

GI number: 15891961

Start: 35819

End: 36058

Strand: Reverse

Name: folKP [H]

Synonym: RC0038

Alternate gene names: 15891961

Gene position: 36058-35819 (Counterclockwise)

Preceding gene: 15891962

Following gene: 15891960

Centisome position: 2.84

GC content: 27.08

Gene sequence:

>240_bases
ATGATTTATATTTCTATAGGCAGTAATTTAGGTAATAAACTTTTAAATATTAAAAAAGCTCTAAATTCATTAAAAAGTTG
TAATTTTATATCGCTTAAGCAAGCTATTATTTTTGAAACACAAGCTATTCTACAACCTAATGCAGATAAAGCTTGGGATA
AATCATATTTAAATATGGTGGTGCAGGGCAAAAGTACTTTAACGCCTAGTAAACTTCTAATTGAGCTTAACAAAGATTGA

Upstream 100 bases:

>100_bases
TAGAAAAGATTTTTCTAAACGTAACCGTTACTAAATTAAAATCACCGGTTTCAGGAGTGCATGGCGGAGTTTCTTTTTCT
TATTCAGGAAAGGAGACACT

Downstream 100 bases:

>100_bases
AAAACAACTAGGTCGAGTAAGCTCTTACGATAAATGGTCTCCAAGAGTTATTGACTTAGATATCCTACTTTGGAATAATT
GCCATATAGATTTACCTGAT

Product: putative folate synthesis bifunctional protein

Products: NA

Alternate protein names: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; PPPK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; HPPK; Dihydropteroate synthase; DHPS; Dihydropteroate pyrophosphorylase [H]

Number of amino acids: Translated: 79; Mature: 79

Protein sequence:

>79_residues
MIYISIGSNLGNKLLNIKKALNSLKSCNFISLKQAIIFETQAILQPNADKAWDKSYLNMVVQGKSTLTPSKLLIELNKD

Sequences:

>Translated_79_residues
MIYISIGSNLGNKLLNIKKALNSLKSCNFISLKQAIIFETQAILQPNADKAWDKSYLNMVVQGKSTLTPSKLLIELNKD
>Mature_79_residues
MIYISIGSNLGNKLLNIKKALNSLKSCNFISLKQAIIFETQAILQPNADKAWDKSYLNMVVQGKSTLTPSKLLIELNKD

Specific function: Unknown

COG id: COG0801

COG function: function code H; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006390
- InterPro:   IPR011005
- InterPro:   IPR000550
- InterPro:   IPR000489 [H]

Pfam domain/function: PF01288 HPPK; PF00809 Pterin_bind [H]

EC number: =2.7.6.3; =2.5.1.15 [H]

Molecular weight: Translated: 8796; Mature: 8796

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYISIGSNLGNKLLNIKKALNSLKSCNFISLKQAIIFETQAILQPNADKAWDKSYLNMV
CEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEE
VQGKSTLTPSKLLIELNKD
ECCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MIYISIGSNLGNKLLNIKKALNSLKSCNFISLKQAIIFETQAILQPNADKAWDKSYLNMV
CEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEE
VQGKSTLTPSKLLIELNKD
ECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]