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The map label for this gene is lysA [H]

Identifier: 57652470

GI number: 57652470

Start: 122908

End: 124110

Strand: Direct

Name: lysA [H]

Synonym: SACOL0107

Alternate gene names: 57652470

Gene position: 122908-124110 (Clockwise)

Preceding gene: 57652469

Following gene: 57652471

Centisome position: 4.37

GC content: 36.66

Gene sequence:

>1203_bases
ATGCGTATAGTTCAACCTGTTATTGAACAATTAAAAGCACAATCTCATCCAGTTTGTCATTATATCTATGATTTAGTCGG
ACTGGAACATCATTTGCAACATATTACATCGTCATTGCCGAGTAATTGTCAAATGTACTATGCAATGAAAGCAAATAGTG
AACGAAAAATCCTAGATACAATTAGTCAGTATGTTGAAGGATTCGAAGTTGCATCTCAAGGTGAAATAGCAAAAGGTCTT
GCTTTTAAACCAGCAAATCATATTATTTTTGGTGGCCCTGGTAAGACAGACGAGGAACTAAGATATGCAGTAAGTGAAGG
TGTTCAGCGTATTCATGTTGAAAGTATGCATGAATTACAACGGCTAAATGCCATCTTAGAAGATGAAGATAAGACACAAC
ACATTTTATTGCGTGTTAATTTAGCAGGACCATTTCCCAATGCAACGTTGCATATGGCAGGACGCCCAACACAATTTGGT
ATTTCTGAAGACGAAGTTGATGATGTCATTGAAGCTGCGCTCGCAATGCCAAAGATTCATCTAGATGGATTTCATTTTCA
TTCTATTTCTAACAATTTAGACTCGAATTTACATGTCGATGTAGTGAAACTTTATTTTAAAAAAGCAAAGGCATGGTCTG
AAAAACATCGATTTCCACTCAAACATATCAATCTTGGTGGTGGCATAGGCGTTAACTATGCAGATTTAACTAACCAATTT
GAATGGGATAATTTTGTAGAACGTTTTAAAACACTTATCGTTGAGCAAGAAATGGAAGATGTGACATTGAACTTTGAATG
TGGGCGCTTTATTGTGGCACATATTGGTTACTATGTGACAGAAGTGCTAGACATTAAGAAAGTACATGGTGCTTGGTATG
CCATATTAAGAGGAGGTACGCAACAATTTAGACTGCCGGTATCTTGGCAACATAACCATCCTTTTGACATTTATCGCTAT
AAGGACAATCCATATTCATTTGAAAAAGTTTCAATTTCGAGACAGGACACAACGTTAGTCGGTCAATTATGTACACCGAA
AGATGTCTTTGCTAGAGAAGTACAGATAGACGCAATCAGTACAGGCGACGTTATTGTTTTCAAATATGCAGGTGCATACG
GATGGTCTATTTCACATCACGATTTCTTAAGCCATCCACATCCTGAATTTATTTATTTAACGCAAACAAAGGAGGATGAA
TAA

Upstream 100 bases:

>100_bases
AAGGTGTACAAACATTTATTTTAGGTGATGATCGCGGAAAAATATATCGCCATTTAAGTGCATCTCTAGCGACGTCTAAA
CAGAAAGGGGATGAAGGCTA

Downstream 100 bases:

>100_bases
CTATTGAATCATATTCATGAACATTTAAAATTGGTACCAGTAGATAAGATTGATCTTCACGAAACATTCGAACCTTTAAG
ATTGGAAAAAACGAAAAGTA

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQMYYAMKANSERKILDTISQYVEGFEVASQGEIAKGL
AFKPANHIIFGGPGKTDEELRYAVSEGVQRIHVESMHELQRLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFG
ISEDEVDDVIEAALAMPKIHLDGFHFHSISNNLDSNLHVDVVKLYFKKAKAWSEKHRFPLKHINLGGGIGVNYADLTNQF
EWDNFVERFKTLIVEQEMEDVTLNFECGRFIVAHIGYYVTEVLDIKKVHGAWYAILRGGTQQFRLPVSWQHNHPFDIYRY
KDNPYSFEKVSISRQDTTLVGQLCTPKDVFAREVQIDAISTGDVIVFKYAGAYGWSISHHDFLSHPHPEFIYLTQTKEDE

Sequences:

>Translated_400_residues
MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQMYYAMKANSERKILDTISQYVEGFEVASQGEIAKGL
AFKPANHIIFGGPGKTDEELRYAVSEGVQRIHVESMHELQRLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFG
ISEDEVDDVIEAALAMPKIHLDGFHFHSISNNLDSNLHVDVVKLYFKKAKAWSEKHRFPLKHINLGGGIGVNYADLTNQF
EWDNFVERFKTLIVEQEMEDVTLNFECGRFIVAHIGYYVTEVLDIKKVHGAWYAILRGGTQQFRLPVSWQHNHPFDIYRY
KDNPYSFEKVSISRQDTTLVGQLCTPKDVFAREVQIDAISTGDVIVFKYAGAYGWSISHHDFLSHPHPEFIYLTQTKEDE
>Mature_400_residues
MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQMYYAMKANSERKILDTISQYVEGFEVASQGEIAKGL
AFKPANHIIFGGPGKTDEELRYAVSEGVQRIHVESMHELQRLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFG
ISEDEVDDVIEAALAMPKIHLDGFHFHSISNNLDSNLHVDVVKLYFKKAKAWSEKHRFPLKHINLGGGIGVNYADLTNQF
EWDNFVERFKTLIVEQEMEDVTLNFECGRFIVAHIGYYVTEVLDIKKVHGAWYAILRGGTQQFRLPVSWQHNHPFDIYRY
KDNPYSFEKVSISRQDTTLVGQLCTPKDVFAREVQIDAISTGDVIVFKYAGAYGWSISHHDFLSHPHPEFIYLTQTKEDE

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322664, Length=385, Percent_Identity=23.1168831168831, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 45760; Mature: 45760

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00879 ODR_DC_2_2 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQMYYAMKANSERKILDT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
ISQYVEGFEVASQGEIAKGLAFKPANHIIFGGPGKTDEELRYAVSEGVQRIHVESMHELQ
HHHHHHHHCCCCCCCHHCCCEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFGISEDEVDDVIEAALAMPKIH
HHHHHHCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEE
LDGFHFHSISNNLDSNLHVDVVKLYFKKAKAWSEKHRFPLKHINLGGGIGVNYADLTNQF
ECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCHHHHCCCC
EWDNFVERFKTLIVEQEMEDVTLNFECGRFIVAHIGYYVTEVLDIKKVHGAWYAILRGGT
CHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
QQFRLPVSWQHNHPFDIYRYKDNPYSFEKVSISRQDTTLVGQLCTPKDVFAREVQIDAIS
HHEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCEEEECCCCCHHHHHHEEEEEEEC
TGDVIVFKYAGAYGWSISHHDFLSHPHPEFIYLTQTKEDE
CCCEEEEEECCCCCCCCCCCHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQMYYAMKANSERKILDT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
ISQYVEGFEVASQGEIAKGLAFKPANHIIFGGPGKTDEELRYAVSEGVQRIHVESMHELQ
HHHHHHHHCCCCCCCHHCCCEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFGISEDEVDDVIEAALAMPKIH
HHHHHHCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEE
LDGFHFHSISNNLDSNLHVDVVKLYFKKAKAWSEKHRFPLKHINLGGGIGVNYADLTNQF
ECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCHHHHCCCC
EWDNFVERFKTLIVEQEMEDVTLNFECGRFIVAHIGYYVTEVLDIKKVHGAWYAILRGGT
CHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
QQFRLPVSWQHNHPFDIYRYKDNPYSFEKVSISRQDTTLVGQLCTPKDVFAREVQIDAIS
HHEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCEEEECCCCCHHHHHHEEEEEEEC
TGDVIVFKYAGAYGWSISHHDFLSHPHPEFIYLTQTKEDE
CCCEEEEEECCCCCCCCCCCHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA