Click here to switch to the map view.

The map label for this gene is aur [H]

Identifier: 57652377

GI number: 57652377

Start: 2720850

End: 2722379

Strand: Reverse

Name: aur [H]

Synonym: SACOL2659

Alternate gene names: 57652377

Gene position: 2722379-2720850 (Counterclockwise)

Preceding gene: 57652378

Following gene: 57652376

Centisome position: 96.9

GC content: 35.69

Gene sequence:

>1530_bases
GTGAGGAAATTTTCAAGATATGCATTTACAAGTATGGCAGCATTAACCTTGTTGAGCACTTTATCACCAGCAGCATTAGC
GATTGATTCAAAAAATAAACCAGCTAATTCTGATATTAAATTTGAGGTGACTCAAAAGAGTGATGCGGTCAAAGCATTAA
AAGAATTGCCTAAATCCGAAAATGTAAAAAATATTTATCAAGATTACGCTGTTACTGATGTAAAAACTGATAAAAAAGGA
TTTACGCATTATACATTGCAACCGAGTGTTGATGGTGTTCATGCACCTGACAAAGAAGTGAAAGTACACGCAGACAAATC
AGGAAAAGTCGTTTTAATCAATGGGGATACTGATGCGAAGAAAGTAAAGCCAACGAATAAAGTGACATTAAGTAAAGATG
ACGCAGCCGACAAAGCATTTAAAGCAGTTAAGATTGATAAGAATAAAGCGAAAAATCTTAAAGATAAAGTCATTAAAGAA
AACAAAGTTGAAATCGATGGTGACAGTAATAAATACGTTTATAATGTTGAGTTAATTACAGTGACACCAGAAATTTCACA
TTGGAAAGTTAAAATTGATGCTCAAACTGGCGAAATTTTAGAAAAAATGAACTTAGTTAAAGAAGCTGCAGAAACTGGTA
AAGGAAAAGGTGTACTTGGCGATACAAAAGATATCAATATCAATAGTATTGACGGTGGATTTAGCCTAGAAGATTTAACG
CATCAAGGTAAATTATCAGCATTTAGCTTTAATGATCAAACAGGTCAAGCAACATTGATTACTAATGAAGATGAAAACTT
CGTAAAAGATGAGCAACGTGCTGGCGTAGATGCAAATTATTACGCTAAACAAACATATGATTATTACAAAGACACATTTG
GTCGTGAATCATATGACAACCAAGGTAGTCCAATTGTTTCATTAACGCATGTTAATAACTACGGTGGTCAAGATAACAGA
AATAATGCCGCATGGATCGGTGACAAAATGATCTATGGTGATGGTGATGGTCGCACATTCACAAGTTTATCGGGTGCAAA
TGACGTAGTAGCACACGAATTAACACACGGTGTGACACAAGAGACAGCGAACTTAGAATATAAGGACCAGTCAGGCGCTC
TAAATGAAAGCTTTTCAGATGTTTTTGGATACTTTGTAGATGACGAGGATTTCTTAATGGGTGAAGATGTCTACACACCT
GGAAAAGAGGGAGACGCTTTACGCAGCATGTCAAACCCAGAACAATTTGGTCAACCAGCTCATATGAAAGACTATGTATT
CACTGAAAAAGATAATGGTGGCGTACATACGAATTCTGGAATTCCAAATAAAGCAGCTTATAACGTGATTCAAGCAATAG
GGAAATCTAAATCAGAACAAATTTACTACCGAGCATTAACGGAATACTTAACAAGTAATTCAAACTTCAAAGATTGTAAA
GATGCATTATACCAAGCGGCTAAAGATTTATATGACGAGCAAACAGCTGAACAGGTGTATGAAGCATGGAATGAAGTAGG
CGTGGAGTAA

Upstream 100 bases:

>100_bases
AAAAGTATAGAAATAAATAGAAATAATCATTTACTTTTCTGAAAAATTAAATTAATATTTTATTTATAAGCTGTTTTTAA
GATTTCAGGAGGAATGAAAT

Downstream 100 bases:

>100_bases
AAATATATAAACAAGAAGAAGTAATGTTAAACACTTATAAATAATTAAATTTTAAATACAGCTTATATATGGGGTATACC
TACATTGATAATTGACTTTG

Product: zinc metalloproteinase aureolysin

Products: NA

Alternate protein names: Staphylococcus aureus neutral proteinase [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MRKFSRYAFTSMAALTLLSTLSPAALAIDSKNKPANSDIKFEVTQKSDAVKALKELPKSENVKNIYQDYAVTDVKTDKKG
FTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLINGDTDAKKVKPTNKVTLSKDDAADKAFKAVKIDKNKAKNLKDKVIKE
NKVEIDGDSNKYVYNVELITVTPEISHWKVKIDAQTGEILEKMNLVKEAAETGKGKGVLGDTKDININSIDGGFSLEDLT
HQGKLSAFSFNDQTGQATLITNEDENFVKDEQRAGVDANYYAKQTYDYYKDTFGRESYDNQGSPIVSLTHVNNYGGQDNR
NNAAWIGDKMIYGDGDGRTFTSLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTP
GKEGDALRSMSNPEQFGQPAHMKDYVFTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCK
DALYQAAKDLYDEQTAEQVYEAWNEVGVE

Sequences:

>Translated_509_residues
MRKFSRYAFTSMAALTLLSTLSPAALAIDSKNKPANSDIKFEVTQKSDAVKALKELPKSENVKNIYQDYAVTDVKTDKKG
FTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLINGDTDAKKVKPTNKVTLSKDDAADKAFKAVKIDKNKAKNLKDKVIKE
NKVEIDGDSNKYVYNVELITVTPEISHWKVKIDAQTGEILEKMNLVKEAAETGKGKGVLGDTKDININSIDGGFSLEDLT
HQGKLSAFSFNDQTGQATLITNEDENFVKDEQRAGVDANYYAKQTYDYYKDTFGRESYDNQGSPIVSLTHVNNYGGQDNR
NNAAWIGDKMIYGDGDGRTFTSLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTP
GKEGDALRSMSNPEQFGQPAHMKDYVFTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCK
DALYQAAKDLYDEQTAEQVYEAWNEVGVE
>Mature_509_residues
MRKFSRYAFTSMAALTLLSTLSPAALAIDSKNKPANSDIKFEVTQKSDAVKALKELPKSENVKNIYQDYAVTDVKTDKKG
FTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLINGDTDAKKVKPTNKVTLSKDDAADKAFKAVKIDKNKAKNLKDKVIKE
NKVEIDGDSNKYVYNVELITVTPEISHWKVKIDAQTGEILEKMNLVKEAAETGKGKGVLGDTKDININSIDGGFSLEDLT
HQGKLSAFSFNDQTGQATLITNEDENFVKDEQRAGVDANYYAKQTYDYYKDTFGRESYDNQGSPIVSLTHVNNYGGQDNR
NNAAWIGDKMIYGDGDGRTFTSLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTP
GKEGDALRSMSNPEQFGQPAHMKDYVFTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCK
DALYQAAKDLYDEQTAEQVYEAWNEVGVE

Specific function: Unknown

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.29 [H]

Molecular weight: Translated: 56362; Mature: 56362

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFSRYAFTSMAALTLLSTLSPAALAIDSKNKPANSDIKFEVTQKSDAVKALKELPKSE
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCCCC
NVKNIYQDYAVTDVKTDKKGFTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLINGDTDAK
CHHHHHHHHHEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCC
KVKPTNKVTLSKDDAADKAFKAVKIDKNKAKNLKDKVIKENKVEIDGDSNKYVYNVELIT
CCCCCCCEEECCCCCHHHHHEEEEECCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEEE
VTPEISHWKVKIDAQTGEILEKMNLVKEAAETGKGKGVLGDTKDININSIDGGFSLEDLT
ECCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCHHHHC
HQGKLSAFSFNDQTGQATLITNEDENFVKDEQRAGVDANYYAKQTYDYYKDTFGRESYDN
CCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
QGSPIVSLTHVNNYGGQDNRNNAAWIGDKMIYGDGDGRTFTSLSGANDVVAHELTHGVTQ
CCCCEEEEEEECCCCCCCCCCCEEEEECEEEEECCCCCEEEECCCCCHHHHHHHHHCHHH
ETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPA
HHCCCEECCCCCCCCCCHHHHHHEEECCCCEEECCCCCCCCCCCHHHHHCCCHHHHCCCC
HMKDYVFTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCK
CCCCEEEEECCCCCEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHH
DALYQAAKDLYDEQTAEQVYEAWNEVGVE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKFSRYAFTSMAALTLLSTLSPAALAIDSKNKPANSDIKFEVTQKSDAVKALKELPKSE
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCCCC
NVKNIYQDYAVTDVKTDKKGFTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLINGDTDAK
CHHHHHHHHHEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCC
KVKPTNKVTLSKDDAADKAFKAVKIDKNKAKNLKDKVIKENKVEIDGDSNKYVYNVELIT
CCCCCCCEEECCCCCHHHHHEEEEECCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEEE
VTPEISHWKVKIDAQTGEILEKMNLVKEAAETGKGKGVLGDTKDININSIDGGFSLEDLT
ECCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCHHHHC
HQGKLSAFSFNDQTGQATLITNEDENFVKDEQRAGVDANYYAKQTYDYYKDTFGRESYDN
CCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
QGSPIVSLTHVNNYGGQDNRNNAAWIGDKMIYGDGDGRTFTSLSGANDVVAHELTHGVTQ
CCCCEEEEEEECCCCCCCCCCCEEEEECEEEEECCCCCEEEECCCCCHHHHHHHHHCHHH
ETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPA
HHCCCEECCCCCCCCCCHHHHHHEEECCCCEEECCCCCCCCCCCHHHHHCCCHHHHCCCC
HMKDYVFTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCK
CCCCEEEEECCCCCEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHH
DALYQAAKDLYDEQTAEQVYEAWNEVGVE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9753696 [H]