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The map label for this gene is recG

Identifier: 57651795

GI number: 57651795

Start: 1249596

End: 1251656

Strand: Direct

Name: recG

Synonym: SACOL1241

Alternate gene names: 57651795

Gene position: 1249596-1251656 (Clockwise)

Preceding gene: 57651794

Following gene: 57651796

Centisome position: 44.48

GC content: 33.58

Gene sequence:

>2061_bases
TTGGCTAAAGTAAACTTAATAGAAAGTCCATATTCTCTTTTACAATTAAAAGGTATAGGTCCTAAGAAAATAGAAGTATT
GCAACAACTAAATATTCATACAGTGGAAGATCTTGTTCTTTATTTGCCAACTAGATATGAAGATAATACAGTGATTGATT
TGAATCAAGCAGAAGATCAATCTAACGTTACGATAGAAGGACAAGTATATACAGCTCCAGTAGTTGCATTTTTTGGAAGA
AATAAATCAAAATTAACCGTTCATTTAATGGTAAATAATATTGCTGTCAAATGTATTTTTTTCAATCAACCGTATTTAAA
AAAGAAAATCGAATTAAATCAAACTATAACTGTTAAAGGTAAGTGGAATAGGGTTAAACAGGAAATTACTGGTAATAGGG
TTTTCTTTAATTCACAAGGGACACAAACTCAAGAAAACGCAGATGTTCAATTAGAACCAGTCTATCGTATTAAGGAAGGT
ATTAAACAAAAGCAAATACGAGACCAAATTAGACAAGCGTTAAATGATGTGACAATTCATGAATGGTTAACTGATGAACT
AAGAGAAAAATATAAATTAGAGACCTTGGACTTTACTTTGAACACATTACATCATCCTAAAAGTAAAGAGGATTTATTAC
GTGCTCGTAGAACCTATGCATTTACTGAACTGTTTTTATTCGAATTACGTATGCAATGGCTAAATAGATTAGAAAAGTCA
TCTGACGAAGCAATTGAAATTGATTATGACATAGACCAAGTTAAATCATTTATTGATCGTTTACCTTTTGAACTAACTGA
AGCACAGAAATCCAGTGTTAATGAAATTTTTAGAGATTTAAAAGCACCAATACGTATGCATCGATTACTTCAAGGTGATG
TAGGTTCAGGAAAAACAGTAGTTGCTGCAATTTGTATGTATGCGTTAAAAACTGCTGGTTATCAATCAGCATTGATGGTA
CCAACTGAAATTTTAGCAGAGCAACATGCTGAAAGTTTAATGGCTTTATTTGGAGATTCTATGAACGTTGCATTGTTAAC
TGGGTCAGTAAAAGGTAAGAAACGAAAGATACTTTTAGAACAACTTGAAAATGGTACGATTGATTGTTTAATTGGAACCC
ATGCTTTGATTCAAGATGATGTGATTTTCCATAATGTTGGTTTAGTAATTACAGATGAACAACATCGATTTGGTGTGAAT
CAACGCCAGCTTTTAAGAGAAAAAGGTGCAATGACGAATGTGTTATTTATGACAGCAACGCCGATACCAAGAACACTAGC
AATATCAGTTTTTGGTGAGATGGATGTGTCTTCAATTAAACAATTACCAAAAGGTCGTAAACCTATCATTACTACTTGGG
CAAAGCATGAGCAATACGATAAAGTTTTGATGCAAATGACCTCAGAGTTGAAAAAAGGTCGTCAAGCATATGTCATTTGC
CCGCTAATAGAAAGTTCTGAGCATCTCGAAGATGTTCAAAATGTTGTCGCATTGTACGAGTCTTTACAACAGTATTATGG
TGTTTCCCGTGTAGGGTTATTGCATGGTAAGTTATCTGCCGATGAAAAAGATGAGGTCATGCAAAAGTTTAGTAATCATG
AGATAAATGTTTTAGTTTCTACTACTGTTGTTGAAGTAGGTGTTAATGTACCGAATGCAACTTTTATGATGATTTATGAT
GCGGATCGCTTTGGATTATCAACTTTACATCAGTTACGCGGTCGTGTAGGTAGAAGTGACCAGCAAAGTTACTGTGTTTT
AATTGCATCCCCTAAAACAGAAACAGGAATTGAAAGAATGACAATTATGACACAAACAACGGATGGATTTGAATTGAGTG
AACGAGACTTAGAAATGCGTGGTCCTGGAGATTTCTTTGGTGTTAAACAAAGTGGATTGCCAGATTTCTTAGTTGCCAAT
TTAGTTGAAGATTATCGTATGTTAGAAGTTGCTCGTGATGAAGCAGCTGAACTTATTCAATCTGGCGTATTCTTTGAAAA
TACGTATCAACATTTACGTCATTTTGTTGAAGAAAATTTATTACATCGTAGTTTTGACTAA

Upstream 100 bases:

>100_bases
GTTCTCGAGTTGCTAACAATGTCATGTTCAACTTAGTCATGATAAAATAAATAACATACTAAATGATACGTAAAATCAAA
TAAAACATAGGTGATTTATT

Downstream 100 bases:

>100_bases
TTGCCATGCTGATTTGTCAATTTGAGTGCAACACTTCGTTAATTGAGTGATATGACACTTGAACTATTTAAATGTAAAGT
GGTATTTTAACAATTTATAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGR
NKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEG
IKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKS
SDEAIEIDYDIDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMV
PTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVN
QRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVIC
PLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEINVLVSTTVVEVGVNVPNATFMMIYD
ADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVAN
LVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD

Sequences:

>Translated_686_residues
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGR
NKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEG
IKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKS
SDEAIEIDYDIDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMV
PTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVN
QRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVIC
PLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEINVLVSTTVVEVGVNVPNATFMMIYD
ADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVAN
LVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>Mature_685_residues
AKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRN
KSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGI
KQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSS
DEAIEIDYDIDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVP
TEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQ
RQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICP
LIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEINVLVSTTVVEVGVNVPNATFMMIYDA
DRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANL
VEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Escherichia coli, GI2367254, Length=660, Percent_Identity=37.8787878787879, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI1787357, Length=404, Percent_Identity=35.3960396039604, Blast_Score=255, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECG_STAA8 (O50581)

Other databases:

- EMBL:   AB000439
- EMBL:   CP000253
- RefSeq:   YP_499733.1
- ProteinModelPortal:   O50581
- SMR:   O50581
- STRING:   O50581
- EnsemblBacteria:   EBSTAT00000027946
- GeneID:   3919327
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_01194
- eggNOG:   COG1200
- GeneTree:   EBGT00050000023889
- HOGENOM:   HBG747311
- OMA:   ETYWVKH
- ProtClustDB:   PRK10917
- BioCyc:   SAUR93061:SAOUHSC_01194-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- SMART:   SM00487
- SMART:   SM00490
- TIGRFAMs:   TIGR00643

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; SSF50249 Nucleic_acid_OB

EC number: =3.6.4.12

Molecular weight: Translated: 78344; Mature: 78213

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQ
CCCCEEECCCHHHEEECCCCHHHHHHHHHCCCHHHHHHHHEECCCCCCCEEEECCCCCCC
SNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKG
CCEEEEEEEEEHHHHHHHCCCCCEEEEEEEEECEEEEEEEECCCHHHHHEECCCEEEEEC
KWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIH
CHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKS
HHHHHHHHHHHCHHHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEAIEIDYDIDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTV
CCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLE
HHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
QLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTAT
HHCCCCEEEEECCHHHHHCCEEEEECCEEEECCHHHCCCCHHHHHHHCCCCEEEEEEECC
PIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVIC
CCCCEEEEEEECCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEE
PLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEINVLVS
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEE
TTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERM
EEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEE
TIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQ
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGVFFENTYQHLRHFVEENLLHRSFD
CCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQ
CCCEEECCCHHHEEECCCCHHHHHHHHHCCCHHHHHHHHEECCCCCCCEEEECCCCCCC
SNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKG
CCEEEEEEEEEHHHHHHHCCCCCEEEEEEEEECEEEEEEEECCCHHHHHEECCCEEEEEC
KWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIH
CHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKS
HHHHHHHHHHHCHHHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEAIEIDYDIDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTV
CCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLE
HHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
QLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTAT
HHCCCCEEEEECCHHHHHCCEEEEECCEEEECCHHHCCCCHHHHHHHCCCCEEEEEEECC
PIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVIC
CCCCEEEEEEECCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEE
PLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEINVLVS
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEE
TTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERM
EEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEE
TIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQ
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGVFFENTYQHLRHFVEENLLHRSFD
CCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9257758