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The map label for this gene is pheS [H]

Identifier: 57651747

GI number: 57651747

Start: 1155545

End: 1156603

Strand: Direct

Name: pheS [H]

Synonym: SACOL1148

Alternate gene names: 57651747

Gene position: 1155545-1156603 (Clockwise)

Preceding gene: 57651746

Following gene: 57651748

Centisome position: 41.13

GC content: 34.56

Gene sequence:

>1059_bases
ATGTCTGAACAACAAACAATGTCAGAGTTAAAACAACAAGCGCTTGTAGATATTAATGAAGCAAATGATGAACGTGCACT
GCAAGAAGTTAAAGTGAAATACTTAGGTAAAAAAGGGTCAGTTAGCGGACTAATGAAATTGATGAAGGATTTGCCGAATG
AAGATAAACCTGCGTTTGGTCAAAAAGTGAATGAATTGCGTCAAACAATTCAAAATGAATTAGATGAAAGACAACAGATG
TTAGTTAAAGAAAAATTAAATAAGCAATTGGCTGAAGAAACAATTGATGTATCATTACCAGGTCGTCATATTGAAATCGG
TTCAAAGCATCCATTAACACGTACAATAGAAGAAATTGAAGACTTATTCTTAGGTTTAGGTTATGAAATTGTGAATGGAT
ATGAAGTTGAACAAGATCATTATAACTTCGAAATGCTGAATTTACCTAAATCACACCCTGCACGTGATATGCAAGATAGT
TTCTATATTACGGATGAAATTTTATTACGTACGCATACATCACCAGTGCAGGCACGTACGATGGAATCACGTCATGGTCA
AGGTCCAGTTAAAATTATTTGCCCTGGTAAAGTGTATCGTCGTGACTCTGATGATGCGACACATAGTCATCAATTTACAC
AAATCGAAGGATTAGTTGTTGATAAAAACGTTAAAATGAGTGATTTGAAAGGTACTTTAGAATTGTTAGCTAAGAAATTA
TTTGGTGCTGATCGTGAAATTCGTTTACGTCCAAGTTACTTCCCATTCACTGAACCTTCTGTAGAAGTTGATGTGTCATG
TTTTAAATGTAAAGGAAAAGGTTGTAATGTGTGTAAACACACAGGATGGATTGAAATTTTAGGTGCTGGAATGGTACATC
CTAATGTATTAGAAATGGCTGGTTTTGATTCTTCAGAGTACTCTGGATTTGCATTTGGTATGGGACCAGACCGTATTGCA
ATGTTGAAATATGGTATAGAAGATATTCGTCATTTCTATACTAATGATGTGAGATTTTTAGATCAATTTAAAGCGGTAGA
AGATAGAGGTGACATGTAA

Upstream 100 bases:

>100_bases
TTCGTCCCTTATTTTTTAAGAGGATGAAAGTCTTTTTTTAGTTAAACAACAAATATGATAAATAGAAAATGAATAGTTCG
AATAGGGAGGTCAGTGACAT

Downstream 100 bases:

>100_bases
TGTTGATATCAAATGAATGGTTGAAAGAATATGTAACAATCGATGATTCTGTAAGTAATTTGGCAGAACGTATTACGCGC
ACAGGTATTGAAGTGGATGA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFGQKVNELRQTIQNELDERQQM
LVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDS
FYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKL
FGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIA
MLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM

Sequences:

>Translated_352_residues
MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFGQKVNELRQTIQNELDERQQM
LVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDS
FYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKL
FGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIA
MLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
>Mature_351_residues
SEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFGQKVNELRQTIQNELDERQQML
VKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSF
YITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLF
GADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAM
LKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=287, Percent_Identity=30.6620209059233, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4758340, Length=277, Percent_Identity=28.8808664259928, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1788007, Length=338, Percent_Identity=49.7041420118343, Blast_Score=340, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17508957, Length=276, Percent_Identity=28.2608695652174, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32563657, Length=276, Percent_Identity=28.2608695652174, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32566635, Length=243, Percent_Identity=35.3909465020576, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321087, Length=379, Percent_Identity=24.5382585751979, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6325304, Length=327, Percent_Identity=28.1345565749235, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI18858079, Length=271, Percent_Identity=29.520295202952, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17137424, Length=304, Percent_Identity=27.9605263157895, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 40107; Mature: 39976

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHH
QKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEECCCCCCHHHHHHHHH
DLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQART
HHHHHCCHHHHCCEEECCCCCCEEEEECCCCCCCCCCCCCEEEHHHHHEEECCCCHHHHH
MESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKL
HHHHCCCCCEEEEECCHHCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
FGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMA
HCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCHHHEEECCCCCCCHHHHC
GFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFG
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHH
QKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEECCCCCCHHHHHHHHH
DLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQART
HHHHHCCHHHHCCEEECCCCCCEEEEECCCCCCCCCCCCCEEEHHHHHEEECCCCHHHHH
MESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKL
HHHHCCCCCEEEEECCHHCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
FGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMA
HCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCHHHEEECCCCCCCHHHHC
GFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA