| Definition | Staphylococcus aureus subsp. aureus COL chromosome, complete genome. |
|---|---|
| Accession | NC_002951 |
| Length | 2,809,422 |
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The map label for this gene is hsdR
Identifier: 57651196
GI number: 57651196
Start: 208190
End: 210979
Strand: Direct
Name: hsdR
Synonym: SACOL0180
Alternate gene names: 57651196
Gene position: 208190-210979 (Clockwise)
Preceding gene: 57651195
Following gene: 57651197
Centisome position: 7.41
GC content: 33.26
Gene sequence:
>2790_bases ATGGCATACCAAAGTGAATACGCATTAGAAAATGAAATGATGAATCAACTTGAACAATTGGGTTACGAAAGAGTAACGAT ACGTGATAATAAGCAATTGCTTGATAATTTTAGAACGATTTTAAATGAGCGTCATGCGGACAAATTAGAAGGCAATCCCT TAACAGATAAAGAATTTCAACGTCTGTTAACGATGATTGATGGAAAAAGTATTTTCGAGAGTGCCCGTATTTTACGTGAT AAATTACCACTTAGACGTGATGATGAGTCTGAGATTTATTTGTCGTTTTTAGATACGAAAAGTTGGTGTAAAAATAAGTT TCAAGTGACGAATCAAGTATCTGTCGAGGATACATATAAAGCACGTTATGATGTAACGATATTAATCAACGGACTACCCC TTGTCCAAGTTGAATTGAAACGTCGAGGTATTGATATTAATGAGGCGTTTAACCAAGTAAAACGTTACCGCAAACAAAAT TACACAGGCTTATTCCGCTACATACAAATGTTTATCATTAGTAATGGTGTTGAAACGCGATACTTTTCTAATAATGATAG CGAACTATTGAAGAGTCACATGTTTTATTGGAGTGATAAACAGAATAACCGTATCAATACATTGCAATCGTTTGCTGAGT CATTTATGAGACCTTGTCAATTAGCTAAGATGATATCGCGCTATATGATTATTAATGAAACAGATAGAATACTGATGGCA ATGCGTCCGTATCAAGTGTATGCGGTAGAAGCACTTATTCAACAAGCGACTGAGACAGGGAATAATGGATATGTATGGCA TACAACTGGAAGTGGTAAGACGTTGACTTCTTTTAAAGCGAGTCAGATTTTATCACAGCAAGATGACATTAAGAAAGTTA TCTTTTTGGTTGACCGTAAAGACTTGGATAGTCAAACAGAAGAGGAATTTAATAAATTTGCTAAGGGTGCTGTAGACAAA ACTTTTAATACCTCGCAACTGGTACGCCAACTAAATGATAAAAGTTTGCCACTTATTGTAACGACGATTCAAAAAATGGC TAAAGCGATTCAAGGGAATGCCCCTTTATTAGAACAGTATAAAACGAATAAAGTTGTATTTATTATTGATGAGTGTCATC GCAGTCAATTTGGTGACATGCATCGTCTAGTTAAACAACATTTCAAAAATGCCCAATACTTTGGATTCACTGGTACGCCA CGTTTTCCAGAAAATAGTAGTCAAGATGGTAGAACAACTGCAGATATTTTCGGTAGATGCTTACATACGTATTTAATTAG AGATGCCATTCATGATGGTAATGTACTTGGTTTCTCAGTTGACTATATTAATACTTTTAAAAATAAAGCTTTAAAAGCAG AAGATAACAGCATGGTTGAAGCAATTGATACGGAAGAAGTATGGTTAGCGGATAAACGTGTGGAATTAGTAACACGACAT ATCATCAATAATCATGATAAATATACACGTAATCGTCAATATTCAAGTATATTTACAGTCCAAAGTATTCACGCGCTTAT TAAATATTATGAGACATTTAAGCGACTTAACAAAAAGTTGGAACAACCGTTAACGATAGCTGGTATATTTACGTTTAAAC CTAATGAAGATGATCGTGATGGTGAAGTGCCATATCATTCACGTGAAAAATTAGAGATAATGATTAGTGATTATAATAAA AAGTTCGAGACGAATTTTTCAACAGACACAACTAATGAGTATTTCAATCATATTTCAAAAAACGTTAAAAAGGGCGTTAA AGATAGTAAAATTGATATCTTAATCGTTGTTAATATGTTCTTAACTGGTTTTGATAGTAAAGTACTGAACACTTTATATG TTGATAAGAATTTAATGTATCATGATTTAATTCAAGCGTATTCACGTACAAATAGGGTTGAAAAAGAATCAAAGCCATTT GGTAAAATTGTAAACTATCGTGACTTGAAAAAAGAGACAGACGATGCACTGAGAGTATTCTCACAAACAAATGATACGGA TACAATTTTAATGCGCAGTTATGAAGAGTATAAAAAAGAATTTATGGACGCTTATCGTGAGCTTAAAATGATTGTGCCGA CACCACACATGGTTGATGACATTCAAGATGAAGAAGAGCTAAAGCGCTTTGTTGAAGCTTATCGTTTATTAGCTAAAATA ATATTACGTTTAAAAGCATTTGACGAGTTTGAGTTTACAATTGATGAAATTGGAATGGATGAACAAGAGAATGAAGACTA TAAAAGTAAATATTTAGCTGTGTACGATCAAGTAAAAAGAGCGACGGCTGAGAAAAATAAAGTATCCATTTTAAATGATA TTGATTTCGAAATAGAAATGATGCGTAATGATACGATTAATGTGAATTATATTATGAATATATTGAGACAAATTGATCTT GAAGACAAAGCGGAACAACGTCGTAACCAAGAACAAATTAGACGCATTTTAGATCATGCAGATGATCCGACATTGAGGTT AAAACGAGATCTAATTAGAGAATTCATCGACAATGTTGTACCTTCTTTAAATAAGGATGATGATATCGATCAAGAATATG TTAATTTCGAAAGTATTAAAAAAGAAGCGGAGTTCAAAGGATTTGCTGGAGAGAGATCTATCGATGAACAAGCCCTAAAA ACAATTTCAAATGACTACCAGTATAGTGGTGTTGTAAACCCACATCACCTTAAAAAAATGATTGGTGATTTGCCATTGAA AGAAAAGCGTAAAGCAAGAAAAGCCATTGAATCTTTCGTGGCAGAAACAACTGAAAAATACGGTGTGTAA
Upstream 100 bases:
>100_bases AAATTAGAATAAATTTACGTTTGAAGATAAAAAACAAACATTTTTCATTAAAGTTTATGATATATTTAGAGCAATAGAAA GTGTATGGAAGGGGATATGA
Downstream 100 bases:
>100_bases TGATTCAGCCCCCTCGCTAGATTAGTGTAGGGGGCATTATTATTTTCTATCTTTTGTTAGTTACCATGTGTTTGGCAACC ATCATTTGGTTTCAATACAA
Product: type I restriction-modification enzyme, R subunit
Products: NA
Alternate protein names: Type I restriction enzyme R protein
Number of amino acids: Translated: 929; Mature: 928
Protein sequence:
>929_residues MAYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNERHADKLEGNPLTDKEFQRLLTMIDGKSIFESARILRD KLPLRRDDESEIYLSFLDTKSWCKNKFQVTNQVSVEDTYKARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQN YTGLFRYIQMFIISNGVETRYFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRPCQLAKMISRYMIINETDRILMA MRPYQVYAVEALIQQATETGNNGYVWHTTGSGKTLTSFKASQILSQQDDIKKVIFLVDRKDLDSQTEEEFNKFAKGAVDK TFNTSQLVRQLNDKSLPLIVTTIQKMAKAIQGNAPLLEQYKTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQYFGFTGTP RFPENSSQDGRTTADIFGRCLHTYLIRDAIHDGNVLGFSVDYINTFKNKALKAEDNSMVEAIDTEEVWLADKRVELVTRH IINNHDKYTRNRQYSSIFTVQSIHALIKYYETFKRLNKKLEQPLTIAGIFTFKPNEDDRDGEVPYHSREKLEIMISDYNK KFETNFSTDTTNEYFNHISKNVKKGVKDSKIDILIVVNMFLTGFDSKVLNTLYVDKNLMYHDLIQAYSRTNRVEKESKPF GKIVNYRDLKKETDDALRVFSQTNDTDTILMRSYEEYKKEFMDAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKI ILRLKAFDEFEFTIDEIGMDEQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEMMRNDTINVNYIMNILRQIDL EDKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVVPSLNKDDDIDQEYVNFESIKKEAEFKGFAGERSIDEQALK TISNDYQYSGVVNPHHLKKMIGDLPLKEKRKARKAIESFVAETTEKYGV
Sequences:
>Translated_929_residues MAYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNERHADKLEGNPLTDKEFQRLLTMIDGKSIFESARILRD KLPLRRDDESEIYLSFLDTKSWCKNKFQVTNQVSVEDTYKARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQN YTGLFRYIQMFIISNGVETRYFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRPCQLAKMISRYMIINETDRILMA MRPYQVYAVEALIQQATETGNNGYVWHTTGSGKTLTSFKASQILSQQDDIKKVIFLVDRKDLDSQTEEEFNKFAKGAVDK TFNTSQLVRQLNDKSLPLIVTTIQKMAKAIQGNAPLLEQYKTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQYFGFTGTP RFPENSSQDGRTTADIFGRCLHTYLIRDAIHDGNVLGFSVDYINTFKNKALKAEDNSMVEAIDTEEVWLADKRVELVTRH IINNHDKYTRNRQYSSIFTVQSIHALIKYYETFKRLNKKLEQPLTIAGIFTFKPNEDDRDGEVPYHSREKLEIMISDYNK KFETNFSTDTTNEYFNHISKNVKKGVKDSKIDILIVVNMFLTGFDSKVLNTLYVDKNLMYHDLIQAYSRTNRVEKESKPF GKIVNYRDLKKETDDALRVFSQTNDTDTILMRSYEEYKKEFMDAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKI ILRLKAFDEFEFTIDEIGMDEQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEMMRNDTINVNYIMNILRQIDL EDKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVVPSLNKDDDIDQEYVNFESIKKEAEFKGFAGERSIDEQALK TISNDYQYSGVVNPHHLKKMIGDLPLKEKRKARKAIESFVAETTEKYGV >Mature_928_residues AYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNERHADKLEGNPLTDKEFQRLLTMIDGKSIFESARILRDK LPLRRDDESEIYLSFLDTKSWCKNKFQVTNQVSVEDTYKARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQNY TGLFRYIQMFIISNGVETRYFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRPCQLAKMISRYMIINETDRILMAM RPYQVYAVEALIQQATETGNNGYVWHTTGSGKTLTSFKASQILSQQDDIKKVIFLVDRKDLDSQTEEEFNKFAKGAVDKT FNTSQLVRQLNDKSLPLIVTTIQKMAKAIQGNAPLLEQYKTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQYFGFTGTPR FPENSSQDGRTTADIFGRCLHTYLIRDAIHDGNVLGFSVDYINTFKNKALKAEDNSMVEAIDTEEVWLADKRVELVTRHI INNHDKYTRNRQYSSIFTVQSIHALIKYYETFKRLNKKLEQPLTIAGIFTFKPNEDDRDGEVPYHSREKLEIMISDYNKK FETNFSTDTTNEYFNHISKNVKKGVKDSKIDILIVVNMFLTGFDSKVLNTLYVDKNLMYHDLIQAYSRTNRVEKESKPFG KIVNYRDLKKETDDALRVFSQTNDTDTILMRSYEEYKKEFMDAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKII LRLKAFDEFEFTIDEIGMDEQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEMMRNDTINVNYIMNILRQIDLE DKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVVPSLNKDDDIDQEYVNFESIKKEAEFKGFAGERSIDEQALKT ISNDYQYSGVVNPHHLKKMIGDLPLKEKRKARKAIESFVAETTEKYGV
Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification
COG id: COG0610
COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 helicase ATP-binding domain
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): HSDR_STAAC (Q5HJH8)
Other databases:
- EMBL: CP000046 - RefSeq: YP_185079.1 - ProteinModelPortal: Q5HJH8 - STRING: Q5HJH8 - REBASE: 10753 - EnsemblBacteria: EBSTAT00000008839 - GeneID: 3236405 - GenomeReviews: CP000046_GR - KEGG: sac:SACOL0180 - TIGR: SACOL0180 - eggNOG: COG0610 - GeneTree: EBGT00050000024583 - HOGENOM: HBG554707 - OMA: RPYQIAA - ProtClustDB: CLSK884469 - BioCyc: SAUR93062:SACOL0180-MONOMER - InterPro: IPR014001 - InterPro: IPR014021 - InterPro: IPR004473 - InterPro: IPR006935 - InterPro: IPR007409 - InterPro: IPR022625 - SMART: SM00487 - TIGRFAMs: TIGR00348
Pfam domain/function: PF12008 EcoR124_C; PF04313 HSDR_N; PF04851 ResIII
EC number: =3.1.21.3
Molecular weight: Translated: 109228; Mature: 109097
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS51192 HELICASE_ATP_BIND_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNERHADKLEGNPLTDKEFQ CCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCHHCCCCCCCHHHHH RLLTMIDGKSIFESARILRDKLPLRRDDESEIYLSFLDTKSWCKNKFQVTNQVSVEDTYK HHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHCCHHHCCCEECCCHHHC ARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQNYTGLFRYIQMFIISNGVETR CEEEEEEEECCCCEEEEHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEE YFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRPCQLAKMISRYMIINETDRILMA EECCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE MRPYQVYAVEALIQQATETGNNGYVWHTTGSGKTLTSFKASQILSQQDDIKKVIFLVDRK ECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCC DLDSQTEEEFNKFAKGAVDKTFNTSQLVRQLNDKSLPLIVTTIQKMAKAIQGNAPLLEQY CCCCHHHHHHHHHHHCHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHH KTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQYFGFTGTPRFPENSSQDGRTTADIFGRC CCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHH LHTYLIRDAIHDGNVLGFSVDYINTFKNKALKAEDNSMVEAIDTEEVWLADKRVELVTRH HHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH IINNHDKYTRNRQYSSIFTVQSIHALIKYYETFKRLNKKLEQPLTIAGIFTFKPNEDDRD HHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCC GEVPYHSREKLEIMISDYNKKFETNFSTDTTNEYFNHISKNVKKGVKDSKIDILIVVNMF CCCCCCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHH LTGFDSKVLNTLYVDKNLMYHDLIQAYSRTNRVEKESKPFGKIVNYRDLKKETDDALRVF HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCHHHHCCHHHHHHHHHHHHHHH SQTNDTDTILMRSYEEYKKEFMDAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKI HCCCCCHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHH ILRLKAFDEFEFTIDEIGMDEQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEM HHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEE MRNDTINVNYIMNILRQIDLEDKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVV ECCCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC PSLNKDDDIDQEYVNFESIKKEAEFKGFAGERSIDEQALKTISNDYQYSGVVNPHHLKKM CCCCCCCCCHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH IGDLPLKEKRKARKAIESFVAETTEKYGV HCCCCCHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure AYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNERHADKLEGNPLTDKEFQ CCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCHHCCCCCCCHHHHH RLLTMIDGKSIFESARILRDKLPLRRDDESEIYLSFLDTKSWCKNKFQVTNQVSVEDTYK HHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHCCHHHCCCEECCCHHHC ARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQNYTGLFRYIQMFIISNGVETR CEEEEEEEECCCCEEEEHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEE YFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRPCQLAKMISRYMIINETDRILMA EECCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE MRPYQVYAVEALIQQATETGNNGYVWHTTGSGKTLTSFKASQILSQQDDIKKVIFLVDRK ECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCC DLDSQTEEEFNKFAKGAVDKTFNTSQLVRQLNDKSLPLIVTTIQKMAKAIQGNAPLLEQY CCCCHHHHHHHHHHHCHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHH KTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQYFGFTGTPRFPENSSQDGRTTADIFGRC CCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHH LHTYLIRDAIHDGNVLGFSVDYINTFKNKALKAEDNSMVEAIDTEEVWLADKRVELVTRH HHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH IINNHDKYTRNRQYSSIFTVQSIHALIKYYETFKRLNKKLEQPLTIAGIFTFKPNEDDRD HHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCC GEVPYHSREKLEIMISDYNKKFETNFSTDTTNEYFNHISKNVKKGVKDSKIDILIVVNMF CCCCCCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHH LTGFDSKVLNTLYVDKNLMYHDLIQAYSRTNRVEKESKPFGKIVNYRDLKKETDDALRVF HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCHHHHCCHHHHHHHHHHHHHHH SQTNDTDTILMRSYEEYKKEFMDAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKI HCCCCCHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHH ILRLKAFDEFEFTIDEIGMDEQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEM HHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEE MRNDTINVNYIMNILRQIDLEDKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVV ECCCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC PSLNKDDDIDQEYVNFESIKKEAEFKGFAGERSIDEQALKTISNDYQYSGVVNPHHLKKM CCCCCCCCCHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH IGDLPLKEKRKARKAIESFVAETTEKYGV HCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA