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The map label for this gene is hisC [H]

Identifier: 57651069

GI number: 57651069

Start: 2773463

End: 2774476

Strand: Reverse

Name: hisC [H]

Synonym: SACOL2701

Alternate gene names: 57651069

Gene position: 2774476-2773463 (Counterclockwise)

Preceding gene: 57651070

Following gene: 57651068

Centisome position: 98.76

GC content: 34.52

Gene sequence:

>1014_bases
ATGATTTATATTGATAAAAATGAAAGTCCAGTTACGCCGTTGGATGAAAAAACAATGACGTCTATTATTAGTGCAACGCC
ATATAATTTATATCCTGATGCAGCATATGAACAATTCAAGGAAGCTTATGCTAAGTTTTACGGATTATCGCCTGAACAAA
TTATTGCAGGAAATGGATCTGATGAATTGATTCAAAAGTTAATGCTGATCATGCCAGAAGGTCCGGCATTAACGCTAAAT
CCTGATTTTTTTATGTATCAAGCATATGCGGCACAAGTAAATCGTGAAATTGCATTTGTAGATGCAGGATCAGATTTAAC
GTTTGATTTGGAAACCATTTTAACGAAAATCGATGAAGTACAACCATCATTTTTTATTATGAGTAATCCACATAACCCTT
CAGGCAAGCAATTTGATACGGCATTTTTAACAGCTATTGCAGATAAGATGAAAGCATTAAACGGATACTTTGTCATTGAT
GAAGCATATTTAGATTATGGTACGGCATATGACGTGGAACTGGCACCACACATCTTAAGAATGCGTACATTATCAAAGGC
GTTTGGAATTGCCGGCTTAAGATTAGGTGTCTTAATTAGTACTGCTGGAACGATAAAGCATATTCAAAAAATAGAACATC
CATATCCATTAAATGTATTTACGCTAAATATTGCGACTTATATTTTTAGACATAGAGAAGAGACAAGACAATTTTTAACG
ATGCAACGACAGTTAGCTGAGCAGTTAAAACAAATATTTGATACACATGTTGCAGATAAAATGTCAGTGTTCCCATCAAA
TGCTAATTTTGTACTTACTAAAGGCTCAGCAGCGCAACAATTAGGACAATACGTATATGAACAAGGATTTAAACCTCGCT
TTTATGATGAGCCGGTGATGAAGGGCTATGTAAGATACTCAATTGCAACAGCATCACAGTTAAAGCAATTAGAAGAAATT
GTTAAAGAATGGAGTGCAAAATATGATTTATCAAAAACAACGAAACACAGCTGA

Upstream 100 bases:

>100_bases
ACAAATTGCTGATTCAGCACAACATATTGCTCATGTTGAAGCATTATACAATCACCAGCAGTCTATTTTAATACGTCAGT
CTTAGGGGAGTGTAATTGAA

Downstream 100 bases:

>100_bases
AACGCAACTAAATATTTCAATATCTGATGATCAGTCACCATCGCATATTAATACAGGTGTGGGCTTTTTAAATCATATGT
TAACCTTGTTTACATTTCAT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLN
PDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRQFLT
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEI
VKEWSAKYDLSKTTKHS

Sequences:

>Translated_337_residues
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLN
PDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRQFLT
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEI
VKEWSAKYDLSKTTKHS
>Mature_337_residues
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLN
PDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRQFLT
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEI
VKEWSAKYDLSKTTKHS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=330, Percent_Identity=26.3636363636364, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322075, Length=360, Percent_Identity=27.2222222222222, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38241; Mature: 38241

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGS
CEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEECCCH
DELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEV
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHC
QPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEECHHHHHHHH
MRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRQFLT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEPVM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHH
KGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGS
CEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEECCCH
DELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEV
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHC
QPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEECHHHHHHHH
MRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRQFLT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEPVM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHH
KGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA