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The map label for this gene is cidA

Identifier: 57651051

GI number: 57651051

Start: 2613806

End: 2614201

Strand: Reverse

Name: cidA

Synonym: SACOL2554.1

Alternate gene names: 57651051

Gene position: 2614201-2613806 (Counterclockwise)

Preceding gene: 57651052

Following gene: 57651050

Centisome position: 93.05

GC content: 32.32

Gene sequence:

>396_bases
ATGCACAAAGTCCAATTAATAATCAAACTACTACTACAACTAGGAATCATCATTGTGATTACTTATATTGGCACAGAAAT
TCAAAAGATTTTTCATCTTCCCTTAGCCGGCAGTATTGTTGGTCTATTTTTATTTTATTTACTATTACAATTTAAGATTG
TACCGCTAACTTGGGTAGAAGACGGTGCAAACTTTTTATTAAAGACGATGGTCTTTTTCTTCATACCGTCAGTTGTAGGT
ATTATGGATGTTGCTTCCGAAATTACGCTAAATTATATACTCTTTTTCGCAGTCATTATCATAGGAACATGTATCGTTGC
ATTATCTTCAGGTTATATTGCTGAAAAAATGTCTGTTAAACATAAACATCGTAAAGGTGTAGACGCTTATGAATGA

Upstream 100 bases:

>100_bases
AGTAATACAAACTATAAAAAAAGAGTATTTTTATATTGTGTACGCCATCTTTATAATAGTTATTGTAACAATTTAGACAT
ATTTAGAAAGGGATGGCGCC

Downstream 100 bases:

>100_bases
TTACGTGCAAGCCTTATTAATGATTTTGTTGACTGTCGTTTTATATTATTTCGCTAAAAGGTTACAACAAAAATATCCGA
ACCCATTTTTGAATCCAGCA

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVG
IMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE

Sequences:

>Translated_131_residues
MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVG
IMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
>Mature_131_residues
MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVG
IMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CIDA_STAA1 (A7X6P6)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001443115.1
- STRING:   A7X6P6
- EnsemblBacteria:   EBSTAT00000003487
- GeneID:   5561260
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2525
- eggNOG:   COG1380
- GeneTree:   EBGT00050000025436
- HOGENOM:   HBG697118
- OMA:   IVCRVIP
- ProtClustDB:   CLSK886055
- BioCyc:   SAUR418127:SAHV_2525-MONOMER
- GO:   GO:0019835
- HAMAP:   MF_01143
- InterPro:   IPR005538

Pfam domain/function: PF03788 LrgA

EC number: NA

Molecular weight: Translated: 14730; Mature: 14730

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10a914d8)-; HASH(0x10a44fa0)-; HASH(0xfd80fa0)-; HASH(0x1035c0e0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HKHRKGVDAYE
HHHHCCCCCCH
>Mature Secondary Structure
MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HKHRKGVDAYE
HHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA