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The map label for this gene is supH [H]

Identifier: 57651033

GI number: 57651033

Start: 2597355

End: 2598155

Strand: Reverse

Name: supH [H]

Synonym: SACOL2536

Alternate gene names: 57651033

Gene position: 2598155-2597355 (Counterclockwise)

Preceding gene: 57651036

Following gene: 57651031

Centisome position: 92.48

GC content: 34.21

Gene sequence:

>801_bases
ATGGTTAAGGCTATTGCGGTAGATATGGACGGGACGTTTTTAGATTCAAAAAAGACATATGATAAACTTAGATTTGAAGC
GATTTTTACTGAACTTAGAAATAGAGATATTACATTTATTGCTGCGAGTGGCAATCAATATGCGAAGTTGAAGTCTATTT
TCGGGGATAGAGATATGTATTTTATTTCTGAAAATGGTGCAGTTATTTATAATGGCAATGAGTTATATAATTATAAAAGC
TTTAATCGTCAGGTGTTTCAACAGGTTGTCGATTACTTAAATATGAAGCAAAGTATTGATCAACTCGTCATCTGTGGTTT
GAAAAGCGCGTATATTTTAAAACATACTTCTGAAGCGTTTAAAGAAGATACGAGATTTTATTATCATCAGTTAAAAGAAA
TTGACAGTCTACAGCAATTACCTGAGGATGATTATGTCAAAATAGCATTTAATATTAATCGTGAGACGCATCCGAATGTT
GACGAAGAAGTAGCAACGCAATTCAGCAATGATATTAAACTTGTCTCAAGTGGGAACGATAGCATTGATATTATTATGCC
AAACATGACTAAAGGGCAGGCATTAAAACGATTGTTAGATAAATGGGAAATGTCTCCTTCAGAGCTCATGGCCTTCGGAG
ATGCGAATAATGATAAAGATATGTTAGCGTTCGCTAAGCATAGTTATGTGATGGAAAATAGTCATGATGAAGAATTGTTC
AATATTGCCTCTGCTGTCGCTCCAAGTAATGATAAGCAGGGTGTATTAACGATTATCGAACAAGAAGTGTTGAAAAAGTA
G

Upstream 100 bases:

>100_bases
CAAAATGTGAATATAGGTTCATTGTGGTATGACAAACTTCATTGCTTGTCATGAGATGGATATAATGAAGACGACTAAAA
GAGCAATGAGGAGGATAATC

Downstream 100 bases:

>100_bases
GTAGTATATCATCAATGAAGCAGCTATCATGATACTAAATACATGTTAAATGAAAACTTTGAATACGAATCATCAAATAT
TAATATATCTCAAACAGGTT

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MVKAIAVDMDGTFLDSKKTYDKLRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMYFISENGAVIYNGNELYNYKS
FNRQVFQQVVDYLNMKQSIDQLVICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
DEEVATQFSNDIKLVSSGNDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
NIASAVAPSNDKQGVLTIIEQEVLKK

Sequences:

>Translated_266_residues
MVKAIAVDMDGTFLDSKKTYDKLRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMYFISENGAVIYNGNELYNYKS
FNRQVFQQVVDYLNMKQSIDQLVICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
DEEVATQFSNDIKLVSSGNDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
NIASAVAPSNDKQGVLTIIEQEVLKK
>Mature_266_residues
MVKAIAVDMDGTFLDSKKTYDKLRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMYFISENGAVIYNGNELYNYKS
FNRQVFQQVVDYLNMKQSIDQLVICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
DEEVATQFSNDIKLVSSGNDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
NIASAVAPSNDKQGVLTIIEQEVLKK

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=262, Percent_Identity=36.6412213740458, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI87081790, Length=267, Percent_Identity=36.7041198501873, Blast_Score=167, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30544; Mature: 30544

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAIAVDMDGTFLDSKKTYDKLRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMY
CCEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEE
FISENGAVIYNGNELYNYKSFNRQVFQQVVDYLNMKQSIDQLVICGLKSAYILKHTSEAF
EEECCCEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNVDEEVATQFSNDIKLVSSGND
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCC
SIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
EEEEEECCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHH
NIASAVAPSNDKQGVLTIIEQEVLKK
HHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVKAIAVDMDGTFLDSKKTYDKLRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMY
CCEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEE
FISENGAVIYNGNELYNYKSFNRQVFQQVVDYLNMKQSIDQLVICGLKSAYILKHTSEAF
EEECCCEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNVDEEVATQFSNDIKLVSSGND
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCC
SIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
EEEEEECCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHH
NIASAVAPSNDKQGVLTIIEQEVLKK
HHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]