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The map label for this gene is 57650132

Identifier: 57650132

GI number: 57650132

Start: 883665

End: 885191

Strand: Direct

Name: 57650132

Synonym: SACOL0857

Alternate gene names: NA

Gene position: 883665-885191 (Clockwise)

Preceding gene: 57650131

Following gene: 57650133

Centisome position: 31.45

GC content: 29.67

Gene sequence:

>1527_bases
TTGAAAAATAAATTGCTAGTTTTATCATTGGGAGCATTATGTGTATCACAAATTTGGGAAAGTAATCGTGCGAGTGCAGT
GGTTTCTGGGGAGAAGAATCCATATGTATCTGAGTCGTTGAAACTGACTAATAATAAAAATAAATCTAGAACAGTAGAAG
AGTATAAGAAAAGCTTGGATGATTTAATATGGTCCTTTCCAAACTTAGATAATGAAAGATTTGATAATCCTGAATATAAA
GAAGCTATGAAAAAATATCAACAGAGATTTATGGCTGAAGATGAGGCTTTGAAGAAATTTTTTAGTGAAGAGAAAAAAAT
AAAAAATGGAAATACTGATAATTTAGATTATCTAGGATTATCTCATGAAAGATATGAAAGTGTATTTAATACTTTGAAAA
AACAAAGTGAGGAGTTCTTAAAAGAAATTGAAGATATAAAAAAAGATAACCCTGAATTGAAAGACTTTAATGAAGAGGAG
CAATTAAAGTGCGACTTAGAATTAAACAAATTAGAAAATCAGATATTAATGTTAGGTAAAACATTTTATCAAAACTATAG
AGATGATGTTGAAAGTTTATATAGTAAGTTAGATTTAATTATGGGATATAAAGATGAAGAAAGAGCAAATAAAAAAGCAG
TTAACAAAAGGATGTTAGAAAATAAAAAAGAAGACTTAGAAACCATAATTGATGAATTTTTTAGTGATATAGATAAAACA
AGACCTAATAATATTCCTGTTTTAGAAGATGAAAAACAAGAAGAGAAAAATCATAAAAATATGGCTCAATTAAAATCTGA
CACTGAAGCAGCAAAAAGTGATGAATCAAAAAGAAGCAAGAGAAGTAAAAGAAGTTTAAATACTCAAAATCACAAACCTG
CATCTCAAGAAGTTTCTGAACAACAAAAAGCTGAATATGATAAAAGAGCAGAAGAAAGAAAAGCGAGATTTTTGGATAAT
CAAAAAATTAAGAAAACACCTGTAGTGTCATTAGAATATGATTTTGAGCATAAACAACGTATTGACAACGAAAACGACAA
GAAACTTGTGGTTTCTGCACCAACAAAGAAACCAACATCACCGACTACATATACTGAAACAACGACACAGGTACCAATGC
CTACAGTTGAGCGTCAAACTCAGCAACAAATTATTTATAATGCACCAAAACAATTGGCTGGATTAAATGGTGAAAGTCAT
GATTTCACAACAACGCATCAATCACCAACAACTTCAAATCACACGCATAATAATGTTGTTGAATTTGAAGAAACGTCTGC
TTTACCTGGTAGAAAATCAGGATCACTGGTTGGTATAAGTCAAATTGATTCTTCTCATCTAACTGAACGTGAGAAGCGTG
TAATTAAGCGTGAACACGTTAGAGAAGCTCAAAAGTTAGTTGATAATTATAAAGATACACATAGTTATAAAGACCGAATA
AATGCACAACAAAAAGTAAATACTTTAAGTGAAGGTCATCAAAAACGTTTTAATAAACAAATCAATAAAGTATATAATGG
CAAATAA

Upstream 100 bases:

>100_bases
TTAATTATTTTAAAAAGGTAGATGTTATATAATTTGGCTTGGCGAAAAAATAGGGTGTAAGGTAGGTTGTTAATTAGGGA
AAATTAAGGAGAAAATACAG

Downstream 100 bases:

>100_bases
TTAATGCATGGCTGCAAAGCAAATAATGAGTTTGTCGTAAAAATAACAACATTTTAAACTAGCAATAAATAATATCAAAG
TCATCATTTCAATGATGCAA

Product: staphylocoagulase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLDDLIWSFPNLDNERFDNPEYK
EAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGLSHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEE
QLKCDLELNKLENQILMLGKTFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKT
RPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSEQQKAEYDKRAEERKARFLDN
QKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTSPTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESH
DFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRI
NAQQKVNTLSEGHQKRFNKQINKVYNGK

Sequences:

>Translated_508_residues
MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLDDLIWSFPNLDNERFDNPEYK
EAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGLSHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEE
QLKCDLELNKLENQILMLGKTFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKT
RPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSEQQKAEYDKRAEERKARFLDN
QKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTSPTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESH
DFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRI
NAQQKVNTLSEGHQKRFNKQINKVYNGK
>Mature_508_residues
MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLDDLIWSFPNLDNERFDNPEYK
EAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGLSHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEE
QLKCDLELNKLENQILMLGKTFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKT
RPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSEQQKAEYDKRAEERKARFLDN
QKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTSPTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESH
DFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRI
NAQQKVNTLSEGHQKRFNKQINKVYNGK

Specific function: Staphylocoagulase is an extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylocoagulase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014874
- InterPro:   IPR001443 [H]

Pfam domain/function: PF08764 Coagulase; PF04022 Staphylcoagulse [H]

EC number: NA

Molecular weight: Translated: 59279; Mature: 59279

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLD
CCCCEEEEHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
DLIWSFPNLDNERFDNPEYKEAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEECC
SHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEEQLKCDLELNKLENQILMLGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCHHHHHHHHHHHHHH
TFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHH
QQKAEYDKRAEERKARFLDNQKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCCCC
PTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESHDFTTTHQSPTTSNHTHNNVV
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCE
EFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRI
EEHHCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAQQKVNTLSEGHQKRFNKQINKVYNGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLD
CCCCEEEEHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
DLIWSFPNLDNERFDNPEYKEAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEECC
SHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEEQLKCDLELNKLENQILMLGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCHHHHHHHHHHHHHH
TFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHH
QQKAEYDKRAEERKARFLDNQKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCCCC
PTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESHDFTTTHQSPTTSNHTHNNVV
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCE
EFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRI
EEHHCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAQQKVNTLSEGHQKRFNKQINKVYNGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2587230; 3941089 [H]