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The map label for this gene is gabP [H]

Identifier: 41410113

GI number: 41410113

Start: 4477977

End: 4478294

Strand: Direct

Name: gabP [H]

Synonym: MAP4015

Alternate gene names: 41410113

Gene position: 4477977-4478294 (Clockwise)

Preceding gene: 41410112

Following gene: 41410117

Centisome position: 92.72

GC content: 66.98

Gene sequence:

>318_bases
ATGGCCCGGGTCGCACCCAACACCGTGTTCCTGTTCCTGCTCAACTCCTCGGGCGCCATCATCCTGTTCGTGTACTGGTT
GATTGCGTTGTCGCAGATCGTCCTTCGCCGCCGGACGCCGGCCGAGCGGCTGAGCGTGAAGATGTGGTTCTTCCCGGTGC
TGTCGGTTCTCACCCTGGCCGGCATCACCGCGGTGCTGGTGCAGATGGCCTTCGACGCCACGGCGCGCAGCCAGTTGTGG
CTCAGCCTGTTGTCCTGGGCGGTGGTGGTGGCGCTGTACTTCGTGGCGTGCTCGCGCGGCCGGGTCGCCGCGCGGTGA

Upstream 100 bases:

>100_bases
GCGGGGCGAGGCACCCGCCCGGTTGGTGCGGCTGAGCGGGCGCGGCGTTCCCCACATCGCCATCCTGTGATCCTCGGCGG
TCGGCTTCCTGTGCGTCGTC

Downstream 100 bases:

>100_bases
CCGCGCTCAGCCGGTGTGCGCGCCGGCGCGGTGCCGTATACCCGCCCCGGCCCGTTCTAGCGGAGCCCGGTCAGCGCCAC
CGCCGTTCGATGGACTTGAC

Product: hypothetical protein

Products: Proton [Cytoplasm]; 4-aminobutyrate [Cytoplasm] [C]

Alternate protein names: 4-amino butyrate transport carrier; Gamma-aminobutyrate permease [H]

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MARVAPNTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFFPVLSVLTLAGITAVLVQMAFDATARSQLW
LSLLSWAVVVALYFVACSRGRVAAR

Sequences:

>Translated_105_residues
MARVAPNTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFFPVLSVLTLAGITAVLVQMAFDATARSQLW
LSLLSWAVVVALYFVACSRGRVAAR
>Mature_104_residues
ARVAPNTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFFPVLSVLTLAGITAVLVQMAFDATARSQLWL
SLLSWAVVVALYFVACSRGRVAAR

Specific function: Transporter for GABA [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840
- InterPro:   IPR011265 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 11702; Mature: 11571

Theoretical pI: Translated: 12.21; Mature: 12.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVAPNTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFFPVLSVLTLA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GITAVLVQMAFDATARSQLWLSLLSWAVVVALYFVACSRGRVAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ARVAPNTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFFPVLSVLTLA
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GITAVLVQMAFDATARSQLWLSLLSWAVVVALYFVACSRGRVAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 4-aminobutyrate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 4-aminobutyrate [Periplasm] = Proton [Cytoplasm] + 4-aminobutyrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8951816; 8969499; 9384377 [H]