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The map label for this gene is scoB

Identifier: 41409959

GI number: 41409959

Start: 4323184

End: 4324533

Strand: Direct

Name: scoB

Synonym: MAP3861

Alternate gene names: 41409959

Gene position: 4323184-4324533 (Clockwise)

Preceding gene: 41409958

Following gene: 41409962

Centisome position: 89.51

GC content: 66.37

Gene sequence:

>1350_bases
GTGAGTAAAGTCCACCCCGACGCGGAATCGGCTCTGCACGGCCTGCTGAAGGACGGCATCACCGTCGCCGCCGGCGGTTT
CGGTCTGTGCGGCATCCCGGAGAAGCTGATCCAGGCGCTGGTGGACAGCGGCATCAAGGACCTCACCATCGTCGGAAACA
ACGCCGGCGTAGACGATTTCGGGATGGGGCTGCTGCTCAAGGGCCGGCAGGTGAAGAAGGTGATCGCCTCCTACGTCGGG
GAGAACAAGGAGTTCGAGCGCCAGGTGCTCTCCGGCGAGCTGGACCTGGTGCTCACCCCGCAGGGCACGCTGGCCGAGAA
ACTGCGCGCCGGCGGCGCGGGCATTCCCGGCTTCTACACCCGCACCGGCTACGGCACCACGCTGGCCGAGGGCAAGGACA
CCCGGGTCTTCGACGGCGTCGAATACGTACTGGAAGAAGGCATTCGGGCCGACCTGGCGATCGTCAAGGCGTGGAAGGGC
GACAAGGCCGGCAACCTCGTCTACCGCAAGACCGCGCGCAACTTCAACCCGATGATCGCCACCTGCGCCGCGGTGACGGT
GGCCGAGGTCGAGGAGCTGGTCGAGGTCGGCGATCTGGACCCCGACCTGATCCACACCCCCGGCATCTACGTGGACCGCA
TCATCCAGGGCATCGGCTACGAGAAGCGCATCGAGTTCCGCACCACCAGCGGCGGCGCCGCGCTGAAGAACGACAGCCCG
ATCCGCGAGCGGATGGCCCAGCGCGCCGCCAAGGAACTGCGCGACGGCTACTACGTCAACCTGGGCATCGGCATCCCGAC
CCTGGTGGCCAATTTCATCCCGGACGATATCCAGGTCACGCTGCAATCGGAGAACGGCCTGCTGGGCATCGGCGCCTATC
CCAGCGAGGACACCGTCGACCCCGACCTCATCAACGCGGGCAAGCAGACCATCACCAGCCTGCCCGGGTCCAGCTTCTTC
TCCAGCGCCGATTCCTTCGCGATGATCCGCGGCGGCCACATCGACCTGTCCATCCTGGGCGCGTTGGAGGTGGCCTCCAA
CGGCGACCTGGCCAACTGGATGGTGCCCGGCAAGATGGTCAAAGGGCCTGGCGGCGCAATGGATTTGGTGTCCGGTGTGA
AGCGGGTGATCGTGCTGATGGACCACACCGCCAAAGACGGCAGCCCGAAGGTCCTCGAGCAGTGCACGTTGCCGCTGACC
GGCAAGGGCGTGGTCGACATGATCATCACCACCCTGTGCGTCTTCGACGTCGAGCCGGGCCGGGGGCTGCTGCTCACCGA
GCTGCATCCGGGGGTGACGGTCGAGGAGGTGCGCGCCAAGACCGGCTGCGACTTCACCGTCGCGCTCTAA

Upstream 100 bases:

>100_bases
TCGCCGAGCGGGACCTGTCGGTGCAGCTGTCGGGGTGGATGCTCATGGAGGCCGCATGTAACGTCTCCGCCGAATCGTCG
CACGAGAACAGGAGCGCCCT

Downstream 100 bases:

>100_bases
AGCCCGGCTACTCGGACGCCGGCAGCCGCTCGGATTCCCGCTCGGGCGTGCGCGTGGGGCGTCGCCGCCCCCGATAGCCC
CGCCAGGCGGCGACGAACGC

Product: ScoB

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTIVGNNAGVDDFGMGLLLKGRQVKKVIASYVG
ENKEFERQVLSGELDLVLTPQGTLAEKLRAGGAGIPGFYTRTGYGTTLAEGKDTRVFDGVEYVLEEGIRADLAIVKAWKG
DKAGNLVYRKTARNFNPMIATCAAVTVAEVEELVEVGDLDPDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSP
IRERMAQRAAKELRDGYYVNLGIGIPTLVANFIPDDIQVTLQSENGLLGIGAYPSEDTVDPDLINAGKQTITSLPGSSFF
SSADSFAMIRGGHIDLSILGALEVASNGDLANWMVPGKMVKGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQCTLPLT
GKGVVDMIITTLCVFDVEPGRGLLLTELHPGVTVEEVRAKTGCDFTVAL

Sequences:

>Translated_449_residues
MSKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTIVGNNAGVDDFGMGLLLKGRQVKKVIASYVG
ENKEFERQVLSGELDLVLTPQGTLAEKLRAGGAGIPGFYTRTGYGTTLAEGKDTRVFDGVEYVLEEGIRADLAIVKAWKG
DKAGNLVYRKTARNFNPMIATCAAVTVAEVEELVEVGDLDPDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSP
IRERMAQRAAKELRDGYYVNLGIGIPTLVANFIPDDIQVTLQSENGLLGIGAYPSEDTVDPDLINAGKQTITSLPGSSFF
SSADSFAMIRGGHIDLSILGALEVASNGDLANWMVPGKMVKGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQCTLPLT
GKGVVDMIITTLCVFDVEPGRGLLLTELHPGVTVEEVRAKTGCDFTVAL
>Mature_448_residues
SKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTIVGNNAGVDDFGMGLLLKGRQVKKVIASYVGE
NKEFERQVLSGELDLVLTPQGTLAEKLRAGGAGIPGFYTRTGYGTTLAEGKDTRVFDGVEYVLEEGIRADLAIVKAWKGD
KAGNLVYRKTARNFNPMIATCAAVTVAEVEELVEVGDLDPDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSPI
RERMAQRAAKELRDGYYVNLGIGIPTLVANFIPDDIQVTLQSENGLLGIGAYPSEDTVDPDLINAGKQTITSLPGSSFFS
SADSFAMIRGGHIDLSILGALEVASNGDLANWMVPGKMVKGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQCTLPLTG
KGVVDMIITTLCVFDVEPGRGLLLTELHPGVTVEEVRAKTGCDFTVAL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=458, Percent_Identity=57.4235807860262, Blast_Score=528, Evalue=1e-150,
Organism=Homo sapiens, GI11545841, Length=456, Percent_Identity=56.140350877193, Blast_Score=494, Evalue=1e-140,
Organism=Escherichia coli, GI1788552, Length=207, Percent_Identity=55.0724637681159, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1788551, Length=202, Percent_Identity=50, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787985, Length=434, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531517, Length=472, Percent_Identity=51.4830508474576, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI21358325, Length=468, Percent_Identity=55.7692307692308, Blast_Score=509, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24655794, Length=468, Percent_Identity=55.7692307692308, Blast_Score=509, Evalue=1e-144,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 47611; Mature: 47480

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01273 COA_TRANSF_1 ; PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTIVGNNAGVDDF
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
GMGLLLKGRQVKKVIASYVGENKEFERQVLSGELDLVLTPQGTLAEKLRAGGAGIPGFYT
CCCEEECCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCEE
RTGYGTTLAEGKDTRVFDGVEYVLEEGIRADLAIVKAWKGDKAGNLVYRKTARNFNPMIA
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHH
TCAAVTVAEVEELVEVGDLDPDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSP
HHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCH
IRERMAQRAAKELRDGYYVNLGIGIPTLVANFIPDDIQVTLQSENGLLGIGAYPSEDTVD
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCC
PDLINAGKQTITSLPGSSFFSSADSFAMIRGGHIDLSILGALEVASNGDLANWMVPGKMV
HHHHHCCHHHHHHCCCCHHHCCCCCEEEEECCCEEEEEEEEEEECCCCCEEEEECCCEEE
KGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQCTLPLTGKGVVDMIITTLCVFDVEPG
CCCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCC
RGLLLTELHPGVTVEEVRAKTGCDFTVAL
CCEEEEECCCCCCHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTIVGNNAGVDDF
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
GMGLLLKGRQVKKVIASYVGENKEFERQVLSGELDLVLTPQGTLAEKLRAGGAGIPGFYT
CCCEEECCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCEE
RTGYGTTLAEGKDTRVFDGVEYVLEEGIRADLAIVKAWKGDKAGNLVYRKTARNFNPMIA
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHH
TCAAVTVAEVEELVEVGDLDPDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSP
HHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCH
IRERMAQRAAKELRDGYYVNLGIGIPTLVANFIPDDIQVTLQSENGLLGIGAYPSEDTVD
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCC
PDLINAGKQTITSLPGSSFFSSADSFAMIRGGHIDLSILGALEVASNGDLANWMVPGKMV
HHHHHCCHHHHHHCCCCHHHCCCCCEEEEECCCEEEEEEEEEEECCCCCEEEEECCCEEE
KGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQCTLPLTGKGVVDMIITTLCVFDVEPG
CCCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCC
RGLLLTELHPGVTVEEVRAKTGCDFTVAL
CCEEEEECCCCCCHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]