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The map label for this gene is 41409843

Identifier: 41409843

GI number: 41409843

Start: 4180326

End: 4181078

Strand: Direct

Name: 41409843

Synonym: MAP3745

Alternate gene names: NA

Gene position: 4180326-4181078 (Clockwise)

Preceding gene: 41409842

Following gene: 41409844

Centisome position: 86.55

GC content: 62.55

Gene sequence:

>753_bases
ATGACCGTGCGTATCGGAGCACTGACCGAACCGACACCCGGCAACCGCACCGTCGTCGTCTTCCCGCACGCGGGCGCCAG
CCCGCGCTTCTACGCTTCCTGGTGCCGCCTACTGCCCGCTGGCGTCGATCTCTACGGTGTCACCTATCCGGGCCGGGACA
TGCTGCTCGACGAGCCCGTACCCGAAACGCTTGCTGACTTGGCCTGCAACTGCGCAGTAGAGCTGAAGCCGATCATCTAC
TCGTCGAGTTCTGTTGTGGTCTTTGGTCATTCGATGGGCAGTCTCGTCGCGTTTGAAACCATCCGAGAACTTGAACAGGA
TGGAGTATCGGTGACTGCTCTGGTCGCTTCAGGGGCGGACGCACCGCATCTGGAAACCGACCAGTCGTGGCACCGTGCTG
CGGACGAGGACCTGATCCAGCACCTGGCCGAACTCGACAGCCGCAGTCGCGACGTGTTCGCCGTACCCGAATTGCGGCGG
ATGTTATTACCCACCGTCCGCGAGGACTTCCGCCTCGTCGAAAGTTATCGCGCCGAGCTGCACCCGCCGGTTTCCTGTCC
CATCCATGTCATGACCGGGGATGCGGATCCTGAAGTGACAGCGCACCGTTGGGCGCAGTGGGCGGTCCACACCCGGGCGC
CCTGGCACGTACGGTCCTTTGCTGGCGACCATTTCTACATCCGTACTCACGAAGACGACGTCGTCAGACACCTATGCGGG
ATTCTCACTTCGGCCCCGGCCGCGACCCAATAG

Upstream 100 bases:

>100_bases
CCACCCGGCTGTGGTCCGAATTTACGTCGGCGATGGGGCCTGCCGCACCGATCAATCCGGTGACATCGGCAAGGCTTTCG
GCCTCGGAGCTGGTTGCCTT

Downstream 100 bases:

>100_bases
CAACGACTGCAAATGCGGCGGTCCAATATCGTCACCGAGTTGCAGGAGAGCGAGGTTGAGCCCGATGACAAGGACACCCG
AAAGCCAGCAGGAAAGCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: ORF-1; Protein X [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTVRIGALTEPTPGNRTVVVFPHAGASPRFYASWCRLLPAGVDLYGVTYPGRDMLLDEPVPETLADLACNCAVELKPIIY
SSSSVVVFGHSMGSLVAFETIRELEQDGVSVTALVASGADAPHLETDQSWHRAADEDLIQHLAELDSRSRDVFAVPELRR
MLLPTVREDFRLVESYRAELHPPVSCPIHVMTGDADPEVTAHRWAQWAVHTRAPWHVRSFAGDHFYIRTHEDDVVRHLCG
ILTSAPAATQ

Sequences:

>Translated_250_residues
MTVRIGALTEPTPGNRTVVVFPHAGASPRFYASWCRLLPAGVDLYGVTYPGRDMLLDEPVPETLADLACNCAVELKPIIY
SSSSVVVFGHSMGSLVAFETIRELEQDGVSVTALVASGADAPHLETDQSWHRAADEDLIQHLAELDSRSRDVFAVPELRR
MLLPTVREDFRLVESYRAELHPPVSCPIHVMTGDADPEVTAHRWAQWAVHTRAPWHVRSFAGDHFYIRTHEDDVVRHLCG
ILTSAPAATQ
>Mature_249_residues
TVRIGALTEPTPGNRTVVVFPHAGASPRFYASWCRLLPAGVDLYGVTYPGRDMLLDEPVPETLADLACNCAVELKPIIYS
SSSVVVFGHSMGSLVAFETIRELEQDGVSVTALVASGADAPHLETDQSWHRAADEDLIQHLAELDSRSRDVFAVPELRRM
LLPTVREDFRLVESYRAELHPPVSCPIHVMTGDADPEVTAHRWAQWAVHTRAPWHVRSFAGDHFYIRTHEDDVVRHLCGI
LTSAPAATQ

Specific function: Probable thioesterase involved in the biosynthesis of candicidin. Could release the macrolide ring from the polyketide synthase [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=219, Percent_Identity=23.7442922374429, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR010693
- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF06902 DUF1271; PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 27640; Mature: 27508

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRIGALTEPTPGNRTVVVFPHAGASPRFYASWCRLLPAGVDLYGVTYPGRDMLLDEPV
CEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEECCCC
PETLADLACNCAVELKPIIYSSSSVVVFGHSMGSLVAFETIRELEQDGVSVTALVASGAD
HHHHHHHHHCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
APHLETDQSWHRAADEDLIQHLAELDSRSRDVFAVPELRRMLLPTVREDFRLVESYRAEL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHC
HPPVSCPIHVMTGDADPEVTAHRWAQWAVHTRAPWHVRSFAGDHFYIRTHEDDVVRHLCG
CCCCCCCEEEEECCCCCCHHHHHHHHHHEECCCCCEEHHCCCCEEEEEECHHHHHHHHHH
ILTSAPAATQ
HHHCCCCCCC
>Mature Secondary Structure 
TVRIGALTEPTPGNRTVVVFPHAGASPRFYASWCRLLPAGVDLYGVTYPGRDMLLDEPV
EEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEECCCC
PETLADLACNCAVELKPIIYSSSSVVVFGHSMGSLVAFETIRELEQDGVSVTALVASGAD
HHHHHHHHHCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
APHLETDQSWHRAADEDLIQHLAELDSRSRDVFAVPELRRMLLPTVREDFRLVESYRAEL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHC
HPPVSCPIHVMTGDADPEVTAHRWAQWAVHTRAPWHVRSFAGDHFYIRTHEDDVVRHLCG
CCCCCCCEEEEECCCCCCHHHHHHHHHHEECCCCCEEHHCCCCEEEEEECHHHHHHHHHH
ILTSAPAATQ
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]