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The map label for this gene is oxyS_2

Identifier: 41409774

GI number: 41409774

Start: 4084364

End: 4085293

Strand: Direct

Name: oxyS_2

Synonym: MAP3676

Alternate gene names: 41409774

Gene position: 4084364-4085293 (Clockwise)

Preceding gene: 41409773

Following gene: 41409775

Centisome position: 84.57

GC content: 71.94

Gene sequence:

>930_bases
ATGCTGTTTCGTCAGCTGGAGTACTTCGTCGCGCTCGCCTCCGAGCGTCACTTCGCGCGGGCCGCCCGCGCGTGCTACGT
GTCCCAGCCCGCGCTCTCGGAGGCCATCCGCAAGCTCGAGCAGGAACTCAACGTGCCCCTGGTGCGTCGCGGGCAGAAGT
TCGAAGGGTTGACGCCCGAGGGCGAGCGGCTGGTGCTGTGGGCGCGGCGCATCCTGGCCGACCACGACGCCCTCAAGCAG
GAGGTCGCCGCGCTGCAGACCGGCCTCACCGGCGAGCTGCGCCTCGGCGTCATCCCGGCGGCCTCGAGCATCGTCGCCCT
GCTCACCGATCCCTTCTGCGCCGCCCATCCGCTGGTGCGGGTGCAGCTCGAGACCAGCCTGCGGTCGGCCGAGATCGTGC
AGCGACTGCGCCGGTTCGAGCTGGACGCCGGGGTCCTCTACCCCGACCGGCAGGATGTCGCCGACCTGCTGGTCACCCCG
CTCTACACCGAGCAGCAGGTGCTCATCGCCGGCGCCGAGTTGCTCCCCGACCCGTCGGAGACCATCAGCTGGTCCGACGC
GCTGACGCTGCCGATGTGCCTGCTGAACCAGGGCATGCGCGGCCGCCGGCTCATCGACGACGCCCTGGCCGCGCTGGAGC
TCACGGTCACGCCGCAGCTCGAGACCGACTCCGTCGCCACGCTGCTGGCGCACGTTGGCACCGGCCGGTGGGCAAGCATC
ATCCCGCAAACCTGGATCCACTCGCTGCGCCCGCCCGCCGGCGCGCGCATCCTGCGGCTGGAGAACCCGACCGTCACCGC
CACGGTCGCGCTGGTCACCAGCGCCACCGAGCCGGGCTCGGTGCTGACCCGCGCGTTGGTGCAGACCGCGCGGGGCGCCG
GCATCAATGACGTGTTGCGCAAGGCCGCGCCCGGATACTCCGCGGGCTAG

Upstream 100 bases:

>100_bases
CGACTACTCGGAGAACCTGCGGCTGACCAACCGCCTCGGTGAGCTCGACGAAACGCTGTGAAAAGCCGCCGCGGCAGCGA
CGGTCATTGACAATGGGCTG

Downstream 100 bases:

>100_bases
CCGCCACCGGCCGTGATCGGCCGGGCCTATCACCCGGTCGGAACTACGTCTTGGACACCCTCGGCGACCGCGCGCGAGAC
TGAAAGTGCTTCGGAAGCGA

Product: OxyS_2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MLFRQLEYFVALASERHFARAARACYVSQPALSEAIRKLEQELNVPLVRRGQKFEGLTPEGERLVLWARRILADHDALKQ
EVAALQTGLTGELRLGVIPAASSIVALLTDPFCAAHPLVRVQLETSLRSAEIVQRLRRFELDAGVLYPDRQDVADLLVTP
LYTEQQVLIAGAELLPDPSETISWSDALTLPMCLLNQGMRGRRLIDDALAALELTVTPQLETDSVATLLAHVGTGRWASI
IPQTWIHSLRPPAGARILRLENPTVTATVALVTSATEPGSVLTRALVQTARGAGINDVLRKAAPGYSAG

Sequences:

>Translated_309_residues
MLFRQLEYFVALASERHFARAARACYVSQPALSEAIRKLEQELNVPLVRRGQKFEGLTPEGERLVLWARRILADHDALKQ
EVAALQTGLTGELRLGVIPAASSIVALLTDPFCAAHPLVRVQLETSLRSAEIVQRLRRFELDAGVLYPDRQDVADLLVTP
LYTEQQVLIAGAELLPDPSETISWSDALTLPMCLLNQGMRGRRLIDDALAALELTVTPQLETDSVATLLAHVGTGRWASI
IPQTWIHSLRPPAGARILRLENPTVTATVALVTSATEPGSVLTRALVQTARGAGINDVLRKAAPGYSAG
>Mature_309_residues
MLFRQLEYFVALASERHFARAARACYVSQPALSEAIRKLEQELNVPLVRRGQKFEGLTPEGERLVLWARRILADHDALKQ
EVAALQTGLTGELRLGVIPAASSIVALLTDPFCAAHPLVRVQLETSLRSAEIVQRLRRFELDAGVLYPDRQDVADLLVTP
LYTEQQVLIAGAELLPDPSETISWSDALTLPMCLLNQGMRGRRLIDDALAALELTVTPQLETDSVATLLAHVGTGRWASI
IPQTWIHSLRPPAGARILRLENPTVTATVALVTSATEPGSVLTRALVQTARGAGINDVLRKAAPGYSAG

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=30.4526748971193, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=202, Percent_Identity=34.1584158415842, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788297, Length=267, Percent_Identity=28.8389513108614, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790208, Length=208, Percent_Identity=31.7307692307692, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787879, Length=253, Percent_Identity=29.2490118577075, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=166, Percent_Identity=31.9277108433735, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33626; Mature: 33626

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRQLEYFVALASERHFARAARACYVSQPALSEAIRKLEQELNVPLVRRGQKFEGLTPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
GERLVLWARRILADHDALKQEVAALQTGLTGELRLGVIPAASSIVALLTDPFCAAHPLVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCHHHCCEEE
VQLETSLRSAEIVQRLRRFELDAGVLYPDRQDVADLLVTPLYTEQQVLIAGAELLPDPSE
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECHHHCCCCCH
TISWSDALTLPMCLLNQGMRGRRLIDDALAALELTVTPQLETDSVATLLAHVGTGRWASI
HCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCCHHHH
IPQTWIHSLRPPAGARILRLENPTVTATVALVTSATEPGSVLTRALVQTARGAGINDVLR
HHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
KAAPGYSAG
HCCCCCCCC
>Mature Secondary Structure
MLFRQLEYFVALASERHFARAARACYVSQPALSEAIRKLEQELNVPLVRRGQKFEGLTPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
GERLVLWARRILADHDALKQEVAALQTGLTGELRLGVIPAASSIVALLTDPFCAAHPLVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCHHHCCEEE
VQLETSLRSAEIVQRLRRFELDAGVLYPDRQDVADLLVTPLYTEQQVLIAGAELLPDPSE
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECHHHCCCCCH
TISWSDALTLPMCLLNQGMRGRRLIDDALAALELTVTPQLETDSVATLLAHVGTGRWASI
HCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCCHHHH
IPQTWIHSLRPPAGARILRLENPTVTATVALVTSATEPGSVLTRALVQTARGAGINDVLR
HHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
KAAPGYSAG
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]