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The map label for this gene is 41409692

Identifier: 41409692

GI number: 41409692

Start: 3990944

End: 3992443

Strand: Direct

Name: 41409692

Synonym: MAP3594

Alternate gene names: NA

Gene position: 3990944-3992443 (Clockwise)

Preceding gene: 41409691

Following gene: 41409693

Centisome position: 82.63

GC content: 68.87

Gene sequence:

>1500_bases
ATGAGCGAGCTGTCGATCGGCATCATCGGCGCCGGTCCGGGCGGCCTGGCGCTGGGAATCCTGCTGTCGCAGGCCGGGTT
TGGTGACTTCACCATCTTCGACCGGGAAGACGGCGTGGGCGGCACCTGGCGGATCAACACCTACCCGGGCCTGGCCTGCG
ACGTCAAATCCCACCTGTACTCGTACTCGTTCGACCTGAACGCGCACTGGTCGCGGCTGTGGTCGGGACAGCCCGAGATC
CTGGACTACTTCCAGCGCTGCGCGGACAAATACGGGCTGGGGCCACATCTGCGGCTGGGCACCGAAATCCGCTCCGCCCA
CTGGGATGCCGACACGCAACGGTGGCGGCTGACCACCGCGTCCGGCCACCGGCACCACTTCGACGTGGTGGTCTCGGCCG
TCGGCCTGTTCACCCGCCCGCTGCTTCCCGAGCTGGTCGAGGAGGAGCCGTTCACCGGGACGGTGATGCACTCGGCGCGC
TGGGACCACTCGATTCCGTTGCACGGCAAACGGATCGCCGTGCTGGGCACCGGGTCCACCGCCTCCCAGCTGATTCCGGA
ATTGGCCAAGGTGGCCGAGCGGGTGTATTCGGTGCAGCGGTCGCCGACCTGGATCCTGCCCAAGCCCGACCGGCCCTACA
CGCAGTGGGAGCGTTGGGCGTTCGCGCACCTGCCGTTGGCGAAGAAGCTCTACCGGACCAGGTTGTGGCTGCGCAGCGAA
TCCAACATCTCGGTGATCGAGCACGGCAGCGAGAAGACCGGGCAATTCACCAACATCGCGCTGGGACTGCTGGAGGCGAG
CGTCCCCGACGAGGAACTGCGCCGCAAGCTCACGCCCGATCATCCGATGGGCTGCAAACGGCTGGTGTTCTCCTCGGACT
ACCTGCCCGCGCTGACCCGGCCCAACGTCGAGGTGCTGACCAGCCCCGCGCGCTCCCTGCGCCGGCGGTCGCTGGTCACC
GAGGACGGCACCGAGCGCGAGGTCGACCTGGTGGTCTGCGCCACCGGCTACGCCGCCGCCGACTATCTCGGCGAACTCGA
CGTGACCGGCGAGCGCGGGGTCACGCTGCGCGAGGTGTGGCGCGACGGCGCCTACGCCTACCTCGGCATGGCCGTACCGG
GATTCCCGAACTTCTTCATGCTGTACGGACCCAACACCAACGTCGGCTCCAACAGCGTCATCTTCGTCCTGGAGGCCCAG
GCCCGCTACATCGTGCGGGCCCTGAAGTATCTGCGCCGCCACCGCCGCCGCTACATCGCGGTGCGGCCCGCCGCGCTGGC
CGACTTCGTCGCCAAGATCGACCGATGGATGGTCGGCACCGTCTGGACCACCCAGTGCAGCAACTACTTTCGCGCCCCCA
ACGGCCGCGTCGTCACCCAGTGGCCGCGCAGCGCACGCGCCTTCTGGTCGATGACGCGCCGGTTCAGGCCGGCCGACTAC
CGGTTCCAGGCGCCGGCGATGCGCGTCCCGGCCCCGGCCTCCGAGGCGGACGCGCGGTGA

Upstream 100 bases:

>100_bases
GTGAGGTCGCCGACGCGGTGGCGTTCCTGGTGTCCGCCGAGGCGTCGTTCATCACCGGCGCCGAACTCATCGTCGATGGC
GGGCAATGCCTGCAGATCCG

Downstream 100 bases:

>100_bases
CGGCGCTGGACGGCGCCGAGCGCCTCGACCCGGCGCTGCGCGCGGTCGCCACCACCCGGACCGACTTCTCGCCCGCCGCA
ATCGAACTCACCCGGGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSELSIGIIGAGPGGLALGILLSQAGFGDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEI
LDYFQRCADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTASGHRHHFDVVVSAVGLFTRPLLPELVEEEPFTGTVMHSAR
WDHSIPLHGKRIAVLGTGSTASQLIPELAKVAERVYSVQRSPTWILPKPDRPYTQWERWAFAHLPLAKKLYRTRLWLRSE
SNISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDHPMGCKRLVFSSDYLPALTRPNVEVLTSPARSLRRRSLVT
EDGTEREVDLVVCATGYAAADYLGELDVTGERGVTLREVWRDGAYAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQ
ARYIVRALKYLRRHRRRYIAVRPAALADFVAKIDRWMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADY
RFQAPAMRVPAPASEADAR

Sequences:

>Translated_499_residues
MSELSIGIIGAGPGGLALGILLSQAGFGDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEI
LDYFQRCADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTASGHRHHFDVVVSAVGLFTRPLLPELVEEEPFTGTVMHSAR
WDHSIPLHGKRIAVLGTGSTASQLIPELAKVAERVYSVQRSPTWILPKPDRPYTQWERWAFAHLPLAKKLYRTRLWLRSE
SNISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDHPMGCKRLVFSSDYLPALTRPNVEVLTSPARSLRRRSLVT
EDGTEREVDLVVCATGYAAADYLGELDVTGERGVTLREVWRDGAYAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQ
ARYIVRALKYLRRHRRRYIAVRPAALADFVAKIDRWMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADY
RFQAPAMRVPAPASEADAR
>Mature_498_residues
SELSIGIIGAGPGGLALGILLSQAGFGDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEIL
DYFQRCADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTASGHRHHFDVVVSAVGLFTRPLLPELVEEEPFTGTVMHSARW
DHSIPLHGKRIAVLGTGSTASQLIPELAKVAERVYSVQRSPTWILPKPDRPYTQWERWAFAHLPLAKKLYRTRLWLRSES
NISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDHPMGCKRLVFSSDYLPALTRPNVEVLTSPARSLRRRSLVTE
DGTEREVDLVVCATGYAAADYLGELDVTGERGVTLREVWRDGAYAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQA
RYIVRALKYLRRHRRRYIAVRPAALADFVAKIDRWMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADYR
FQAPAMRVPAPASEADAR

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=432, Percent_Identity=22.9166666666667, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503757, Length=355, Percent_Identity=24.2253521126761, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503759, Length=359, Percent_Identity=24.7910863509749, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17541300, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25145785, Length=349, Percent_Identity=20.9169054441261, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 56294; Mature: 56163

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSIGIIGAGPGGLALGILLSQAGFGDFTIFDREDGVGGTWRINTYPGLACDVKSHLY
CCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCEEHHHHHHE
SYSFDLNAHWSRLWSGQPEILDYFQRCADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTA
EEEECCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCEEEEEEC
SGHRHHFDVVVSAVGLFTRPLLPELVEEEPFTGTVMHSARWDHSIPLHGKRIAVLGTGST
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCH
ASQLIPELAKVAERVYSVQRSPTWILPKPDRPYTQWERWAFAHLPLAKKLYRTRLWLRSE
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHEEECC
SNISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDHPMGCKRLVFSSDYLPALTR
CCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHEECCCCCCCCCC
PNVEVLTSPARSLRRRSLVTEDGTEREVDLVVCATGYAAADYLGELDVTGERGVTLREVW
CCHHEECCHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCCCHHHHH
RDGAYAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYIVRALKYLRRHRRRYIA
CCCCEEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHEEE
VRPAALADFVAKIDRWMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADY
ECCHHHHHHHHHHHHHHEEEEEEHHHHHHEECCCCCEEECCCHHHHHHHHHHHHCCCCCC
RFQAPAMRVPAPASEADAR
EECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SELSIGIIGAGPGGLALGILLSQAGFGDFTIFDREDGVGGTWRINTYPGLACDVKSHLY
CCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCEEHHHHHHE
SYSFDLNAHWSRLWSGQPEILDYFQRCADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTA
EEEECCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCEEEEEEC
SGHRHHFDVVVSAVGLFTRPLLPELVEEEPFTGTVMHSARWDHSIPLHGKRIAVLGTGST
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCH
ASQLIPELAKVAERVYSVQRSPTWILPKPDRPYTQWERWAFAHLPLAKKLYRTRLWLRSE
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHEEECC
SNISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDHPMGCKRLVFSSDYLPALTR
CCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHEECCCCCCCCCC
PNVEVLTSPARSLRRRSLVTEDGTEREVDLVVCATGYAAADYLGELDVTGERGVTLREVW
CCHHEECCHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCCCHHHHH
RDGAYAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYIVRALKYLRRHRRRYIA
CCCCEEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHEEE
VRPAALADFVAKIDRWMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADY
ECCHHHHHHHHHHHHHHEEEEEEHHHHHHEECCCCCEEECCCHHHHHHHHHHHHCCCCCC
RFQAPAMRVPAPASEADAR
EECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]